Abstract: A ventilator that is small, lightweight, and portable, yet capable of being quickly adapted to operate in a plurality of different modes and configurations to deliver a variety of therapies to a patent. A porting system having a plurality of sensors structured to monitor a number of parameters with respect to the flow of gas, and a number of porting blocks is used to reconfigure the ventilator so that it operates as a single-limb or dual limb ventilator. In the single-limb configuration, an active or passive exhaust assembly can be provided proximate to the patient. The ventilator is capable of operate in a volume or pressure support mode, even in a single-limb configuration. In addition, a power control mechanism controls the supply of power to the ventilator from an AC power source, a lead acid battery, an internal rechargeable battery pack, and a detachable battery pack.

Abstract: A system for controlling machine-induced expiratory airflow of a subject, the subject having an airway, the system comprising: a pressure generator (140) configured to generate a pressurized flow of breathable gas for delivery to the airway of the subject; and one or more processors (110) configured to execute computer program modules, the computer program modules comprising: a control module (170) configured to control the pressure generator a metric determination module (154) configured to determine a value of a flow metric during expiration by the subject, a flow analysis module (156) configured to compare the determined value of the flow metric with a target level of the flow metric; and an adjustment module (160) configured to adjust one or more of exsufflation pressure.

Abstract: A method of assisting a patient with airway clearance includes providing a positive pressure insufflation gas flow to the patient during an insufflation phase, following completion of the insufflation phase, causing the patient to enter an expiratory hold condition wherein the patient is prevented from exhaling, providing an abdominal thrust to the patient while the patient is in the expiratory hold condition, terminating the expiratory hold condition, and following termination of the expiratory hold condition, providing a negative pressure exsufflation gas flow to the patient during an exsufflation phase.

Abstract: A system for controlling machine-induced expiratory airflow of a subject, the subject having an airway, the system comprising: a pressure generator (140) configured to generate a pressurized flow of breathable gas for delivery to the airway of the subject; and one or more processors (110) configured to execute computer program modules, th computer program modules comprising: a control module (170) configured to control the pressure generator a metric determination module (154) configured to determine a value of a flow metric during expiration by the subject, a flow analysis module (156) configured to compare the determined value of the flow metric with a target level of the flow metric; and an adjustment module (160) configured to adjust one or more of exsufflation pressure.