Patents by Inventor Christopher Wilds

Christopher Wilds has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antisense oligonucleotide constructs based on beta-arabinofuranose and its analogues
    Publication number: 20090105467
    Abstract: The present invention relates to modified oligonucleotide therapeutic agents to selectively prevent gene transcription and expression in a sequence-specific manner. In particular, this invention relates to the selective inhibition of protein biosynthesis via antisense strategy using oligonucleotides constructed from arabinonucleotide or modified arabinonucleotide residues. More particularly this invention relates to the use of antisense oligonucleotides having arabinose sugars to hybridize to complementary RNA such as cellular messenger RNA, viral RNA, etc.
    Type: Application
    Filed: June 13, 2007
    Publication date: April 23, 2009
    Applicant: McGill University
    Inventors: Masad J. Damha, Michael A. Parniak, Anne M. Noronha, Christopher Wilds, Gadi Borkow, Dominique Arion