Abstract: Systems, methods, and non-transitory computer-readable media can identify a set of media content items associated with a first user of a social networking system. It can be determined that a second user of the social networking system is attempting to access at least a portion of the set of media content items associated with the first user. A first subset of media content items can be dynamically selected out of the set of media content items. In some cases, each media content item in the first subset can satisfy specified selection criteria. The second user can be provided with access to a representation of the first subset of media content items. In some instances, the representation of the first subset can be provided in a media access interface associated with the first user.

Abstract: Systems, methods, and non-transitory computer-readable media can identify a set of media content items associated with a first user of a social networking system. It can be determined that a second user of the social networking system is attempting to access at least a portion of the set of media content items associated with the first user. A first subset of media content items can be dynamically selected out of the set of media content items. In some cases, each media content item in the first subset can satisfy specified selection criteria. The second user can be provided with access to a representation of the first subset of media content items. In some instances, the representation of the first subset can be provided in a media access interface associated with the first user.

Abstract: A compound of formula (I) as well as pharmaceutically acceptable salt thereof, wherein R1 to R10, A, Q, X and Y are as defined in the specification and claims, and their use as a pharmaceutical for the treatment or prophylaxis of respiratory syncytial virus disease.

Abstract: The present invention relates to a method of coating a porous substrate. The method includes forming a first coating on the substrate that at least partially fills the pores of the substrate, forming a second coating on the substrate, and optionally at least partially restoring the porosity of the porous substrate.

Abstract: The present invention relates to silicone compositions that are useful for the production of membranes that are selectively permeable to at least one component of a gas mixture. The invention provides a method of forming the membrane. The invention also provides a method of separating components in a feed mixture using the membrane. The membrane includes a reaction product (e.g. cured product) of a silicone composition including an organopolysiloxane having at least two unsaturated aliphatic carbon-carbon bond-containing groups per molecule; a crosslinking agent having at least two silicon-bonded hydrogen atoms per molecule; a hydrosilylation catalyst; a polyether containing at least one unsaturated aliphatic carbon-carbon bond-containing group; and a siliceous filler.

Abstract: The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt, ester or stereoisomer thereof, wherein R1 to R3 and X have the significances given herein. The present invention is also directed to processes for making said compounds and uses of said compounds, in particular their use as medicaments, more particularly their use as medicaments in the treatment of cancer.

Abstract: The present invention relates to a membrane including a reaction product of an epoxy-functional organopolysiloxane and an amino-functional curing agent, wherein the organopolysiloxane has an average of at least two silicon-bonded epoxy-substituted organic groups per molecule and the curing agent has an average of at least two nitrogen-bonded hydrogen atoms per molecule. The invention further relates to a method of separating gas components in a feed gas mixture by use of the membrane.

Abstract: The present invention relates to a method of coating a porous substrate. The method includes forming a first coating on the substrate that at least partially fills the pores of the substrate, forming a second coating on the substrate, and optionally at least partially restoring the porosity of the porous substrate.

Abstract: A compound of formula (I) as well as pharmaceutically acceptable salt thereof, wherein R1 to R10, A, Q, X and Y are as defined in the specification and claims, and their use as a pharmaceutical for the treatment or prophylaxis of respiratory syncytial virus disease.

Abstract: The present invention provides compounds of formula or pharmaceutically acceptable salts, esters or stereoisomers thereof, wherein R1 to R4, A and Y have the meanings given herein, as well as methods for making those compounds and their use as medicament, in particular as medicament for the treatment of cancer.

Abstract: The present invention provides compounds of formula or pharmaceutically acceptable salts, esters or stereoisomers thereof, wherein R1 to R4, A and Y have the meanings given herein, as well as methods for making those compounds and their use as medicament, in particular as medicament for the treatment of cancer.

Abstract: A method of sequencing a first polynucleotide strand having a first polynucleotide sequence, the first polynucleotide strand resembling a second polynucleotide strand having a known second polynucleotide sequence, the method employing a data set which, for one or more fragment(s) of the second polynucleotide sequence, contains: for each position along each said fragment: (i) first probe data describing the hybridization intensity of the first polynucleotide strand with a respective first probe designed to bind to a portion of the second polynucleotide strand centered at said position; and (ii) second probe data describing the respective hybridization intensities of the first polynucleotide strand with each of a set of second probes, each said second probe being designed to bind with a respective mutation of the corresponding portion of the second polynucleotide sequence which is formed by mutating the corresponding portion of the second polynucleotide sequence at said position, the data set including said sec

Abstract: The present invention is directed to a compound of formula I, and processes for the manufacture of said compounds as well as medicaments containing said compound. The compounds according to this invention show anti-proliferative and differentiation-inducing activity and are thus useful for the treatment of diseases such as cancer in humans or animals.

Abstract: The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt, ester or stereoisomer thereof, wherein R1 to R3 and X have the significances given herein. The present invention is also directed to processes for making said compounds and uses of said compounds, in particular their use as medicaments, more particularly their use as medicaments in the treatment of cancer.

Abstract: The present invention is directed to the compounds of formula wherein R1 to R4 have the significances given herein, to processes for the manufacture of said compounds as well as medicaments containing said compounds. The compounds according to this invention show anti-proliferative and differentiation-inducing activity and are thus useful for the treatment of diseases such as cancer in humans or animals.

Abstract: Compounds of formula are HDAC inhibitors. These compounds are useful for the treatment of diseases such as cancer in humans or animals.

Abstract: The present invention provides novel compounds of the general formula (I) and pharmaceutically acceptable salts thereof, processes for the manufacture of these novel compounds and medicaments containing such compounds. The compounds of the present invention show anti-proliferative and differentiation-inducing activity, which results in inhibition of tumor cell proliferation, induction of apoptosis and inhibition of invasion. The invention also covers the use of such compounds for the treatment of diseases such as cancer and for the manufacture of corresponding medicaments.

Abstract: Compounds of formula are HDAC inhibitors. These compounds are useful for the treatment of diseases such as cancer in humans or animals.

Abstract: The present invention is directed to a compound of formula I, and processes for the manufacture of said compounds as well as medicaments containing said compound. The compounds according to this invention show anti-proliferative and differentiation-inducing activity and are thus useful for the treatment of diseases such as cancer in humans or animals.

Abstract: The present invention is directed to the compounds of formula wherein R1 to R4 have the significances given herein, to processes for the manufacture of said compounds as well as medicaments containing said compounds. The compounds according to this invention show anti-proliferative and differentiation-inducing activity and are thus useful for the treatment of diseases such as cancer in humans or animals.