Patents by Inventor Christopher Zarins
Christopher Zarins has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20200078094Abstract: Systems and methods are disclosed for assessing organ and/or tissue transplantation by estimating blood flow through a virtual transplant model by receiving a patient-specific anatomical model of the intended transplant recipient; receiving a patient-specific anatomical model of the intended transplant donor, the model including the vasculature of the organ or tissue that is intended to be transplanted to the recipient; constructing a unified model of the connected system post transplantation, the connected system including the transplanted organ or tissue from the intended transplant donor and the vascular system of the intended transplant recipient; receiving one or more blood flow characteristics of the connected system; assessing the suitability for an actual organ or tissue transplantation using the received blood flow characteristics; and outputting the assessment into an electronic storage medium or display.Type: ApplicationFiled: November 11, 2019Publication date: March 12, 2020Inventors: Leo Grady, Charles A. Taylor, Christopher Zarins
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Patent number: 10499990Abstract: Systems and methods are disclosed for assessing organ and/or tissue transplantation by estimating blood flow through a virtual transplant model by receiving a patient-specific anatomical model of the intended transplant recipient; receiving a patient-specific anatomical model of the intended transplant donor, the model including the vasculature of the organ or tissue that is intended to be transplanted to the recipient; constructing a unified model of the connected system post transplantation, the connected system including the transplanted organ or tissue from the intended transplant donor and the vascular system of the intended transplant recipient; receiving one or more blood flow characteristics of the connected system; assessing the suitability for an actual organ or tissue transplantation using the received blood flow characteristics; and outputting the assessment into an electronic storage medium or display.Type: GrantFiled: November 21, 2016Date of Patent: December 10, 2019Assignee: HeartFlow, Inc.Inventors: Leo Grady, Charles A. Taylor, Christopher Zarins
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Patent number: 10304569Abstract: Systems and methods are disclosed for associating medical images with a patient. One method includes: receiving two or more medical images of patient anatomy in an electronic storage medium; generating an anatomical model for each of the received medical images; comparing the generated anatomical models; determining a score assessing the likelihood that the two or more medical images belong to the same patient, using the comparison of the generated anatomical models; and outputting the score to an electronic storage medium or display.Type: GrantFiled: December 2, 2016Date of Patent: May 28, 2019Assignee: HeartFlow, Inc.Inventors: Leo Grady, Christopher Zarins, Edward Karl Hahn, III, Ying Bai, Sethuraman Sankaran, Peter Kersten Petersen, Michiel Schaap
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Patent number: 9993303Abstract: A computer implemented method for assessing an arterio-venous malformation (AVM) may include, for example, receiving a patient-specific model of a portion of an anatomy of a patient; using a computer processor to analyze the patient-specific model for identifying one or more blood vessels associated with the AVM, in the patient-specific model; and estimating a risk of an undesirable outcome caused by the AVM, by performing computer simulations of blood flow through the one or more blood vessels associated with the AVM in the patient-specific model.Type: GrantFiled: November 8, 2017Date of Patent: June 12, 2018Assignee: HeartFlow, Inc.Inventors: Sethuraman Sankaran, Christopher Zarins, Leo Grady
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Publication number: 20180068465Abstract: A computer implemented method for assessing an arterio-venous malformation (AVM) may include, for example, receiving a patient-specific model of a portion of an anatomy of a patient; using a computer processor to analyze the patient-specific model for identifying one or more blood vessels associated with the AVM, in the patient-specific model; and estimating a risk of an undesirable outcome caused by the AVM, by performing computer simulations of blood flow through the one or more blood vessels associated with the AVM in the patient-specific model.Type: ApplicationFiled: November 8, 2017Publication date: March 8, 2018Applicant: HeartFlow, Inc.Inventors: Sethuraman Sankaran, Christopher Zarins, Leo Grady
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Publication number: 20180047304Abstract: Systems and methods are disclosed for identifying and modeling unresolved vessels, and the effects thereof, in image-based patient-specific hemodynamic models. One method includes: receiving a patient-specific anatomical model of at least a portion of a visceral vascular system of the patient; receiving patient-specific information related to the patient's food intake; generating a patient-specific model of blood flow in the patient-specific anatomical model of the portion of the visceral vascular system of the patient; generating a patient-specific model of nutrient transport from at least a part of a gastrointestinal system of the patient to the portion of the visceral vascular system of the patient based on the patient-specific information related to the patient's food intake; and determining an indicia of energy available in the patient based on the patient-specific model of nutrient transport.Type: ApplicationFiled: August 10, 2017Publication date: February 15, 2018Inventors: Sethuraman SANKARAN, Christopher ZARINS, Charles A. TAYLOR, Leo GRADY
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Patent number: 9839483Abstract: A computer implemented method for assessing an arterio-venous malformation (AVM) may include, for example, receiving a patient-specific model of a portion of an anatomy of a patient; using a computer processor to analyze the patient-specific model for identifying one or more blood vessels associated with the AVM, in the patient-specific model; and estimating a risk of an undesirable outcome caused by the AVM, by performing computer simulations of blood flow through the one or more blood vessels associated with the AVM in the patient-specific model.Type: GrantFiled: September 2, 2015Date of Patent: December 12, 2017Assignee: HEARTFLOW, INC.Inventors: Sethuraman Sankaran, Christopher Zarins, Leo J. Grady
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Publication number: 20170333607Abstract: A catheter includes a catheter body, a pump assembly and a cannula. The pump assembly can be disposed at a distal end of the catheter body and has a distal portion. The cannula can be coupled to the distal end portion of the pump assembly and can include a proximal cannula portion and a distal cannula portion. The distal cannula portion has an approximately helical shape which can allow the cannula to be inserted into a patient's right heart and pump blood therethrough. In certain implementations, the distal tip of the helical shape has a slight bias relative to the main helix to further facilitate delivery of the device. In certain applications this bias is toward the central axis of the helix.Type: ApplicationFiled: May 17, 2016Publication date: November 23, 2017Inventor: Christopher Zarins
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Patent number: 9814612Abstract: A positioning anchor is provided for a stent-graft for implantation to treat a damaged body lumen. The positioning anchor is generally tubular surrounding a primary fluid conduit. Arms extend laterally from the generally tubular structure of the anchor surrounding lateral fluid conduits. The form of these arms is preferably custom configured to match a particular patient's luminal geometry. The anchor thus fits within the luminal geometry to remain in a desired fixed position for implantation of the anchor and any stent-graft coupled to the anchor. The anchor is most preferably formed with two walls having a void therebetween which can be filled with fixation media to further secure the anchor at the desired implantation site. A lumen shaper balloon and delivery catheter are also disclosed for proper delivery, expansion and inflation of the positioning anchor and stent-graft elements according to this invention.Type: GrantFiled: October 21, 2015Date of Patent: November 14, 2017Assignee: Nellix, Inc.Inventors: Charles S. Taylor, Christopher Zarins, Robert A. Geshlider, Dwight P. Morejohn, Peter Johansson, Susan W. Vican, James T. McKinley
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Publication number: 20170215918Abstract: A cannula supporting a percutaneous pump can include a proximal section with a first flexural modulus. The cannula can include one or more distal sections with a flexural modulus that is different than the first flexural modulus. The material and its arrangement along the length of the cannula can be selected so as to influence bending properties. This can, for example, allow efficient positioning of the cannula in a desired location without displacing the guidewire.Type: ApplicationFiled: January 30, 2017Publication date: August 3, 2017Inventors: Zhenghong Tao, Christopher Zarins, Dion Mraz, Stephen Vaughan, Julius Steven Becker
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Publication number: 20170161455Abstract: Systems and methods are disclosed for associating medical images with a patient. One method includes: receiving two or more medical images of patient anatomy in an electronic storage medium; generating an anatomical model for each of the received medical images; comparing the generated anatomical models; determining a score assessing the likelihood that the two or more medical images belong to the same patient, using the comparison of the generated anatomical models; and outputting the score to an electronic storage medium or display.Type: ApplicationFiled: December 2, 2016Publication date: June 8, 2017Inventors: Leo GRADY, Christopher ZARINS, Edward Karl HAHN, III, Ying BAI, Sethuraman SANKARAN, Peter Kersten PETERSEN, Michiel SCHAAP
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Publication number: 20170143427Abstract: Systems and methods are disclosed for assessing organ and/or tissue transplantation by estimating blood flow through a virtual transplant model by receiving a patient-specific anatomical model of the intended transplant recipient; receiving a patient-specific anatomical model of the intended transplant donor, the model including the vasculature of the organ or tissue that is intended to be transplanted to the recipient; constructing a unified model of the connected system post transplantation, the connected system including the transplanted organ or tissue from the intended transplant donor and the vascular system of the intended transplant recipient; receiving one or more blood flow characteristics of the connected system; assessing the suitability for an actual organ or tissue transplantation using the received blood flow characteristics; and outputting the assessment into an electronic storage medium or display.Type: ApplicationFiled: November 21, 2016Publication date: May 25, 2017Inventors: Leo GRADY, Charles A. Taylor, Christopher Zarins
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Publication number: 20160314601Abstract: A computer implemented method for assessing an arterio-venous malformation (AVM) may include, for example, receiving a patient-specific model of a portion of an anatomy of a patient; using a computer processor to analyze the patient-specific model for identifying one or more blood vessels associated with the AVM, in the patient-specific model; and estimating a risk of an undesirable outcome caused by the AVM, by performing computer simulations of blood flow through the one or more blood vessels associated with the AVM in the patient-specific model.Type: ApplicationFiled: September 2, 2015Publication date: October 27, 2016Inventors: Sethuraman SANKARAN, Christopher ZARINS, Leo J. GRADY
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Publication number: 20160030215Abstract: A positioning anchor is provided for a stent-graft for implantation to treat a damaged body lumen. The positioning anchor is generally tubular surrounding a primary fluid conduit. Arms extend laterally from the generally tubular structure of the anchor surrounding lateral fluid conduits. The form of these arms is preferably custom configured to match a particular patient's luminal geometry. The anchor thus fits within the luminal geometry to remain in a desired fixed position for implantation of the anchor and any stent-graft coupled to the anchor. The anchor is most preferably formed with two walls having a void therebetween which can be filled with fixation media to further secure the anchor at the desired implantation site. A lumen shaper balloon and delivery catheter are also disclosed for proper delivery, expansion and inflation of the positioning anchor and stent-graft elements according to this invention.Type: ApplicationFiled: October 21, 2015Publication date: February 4, 2016Applicant: NELLIX, INC.Inventors: CHARLES S. TAYLOR, CHRISTOPHER ZARINS, ROBERT A. GESHLIDER, DWIGHT P. MOREJOHN, PETER JOHANSSON, SUSAN W. VICAN, JAMES T. MCKINLEY
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Patent number: 9113999Abstract: A positioning anchor is provided for a stent-graft for implantation to treat a damaged body lumen. The positioning anchor is generally tubular surrounding a primary fluid conduit. Arms extend laterally from the generally tubular structure of the anchor surrounding lateral fluid conduits. The form of these arms is preferably custom configured to match a particular patient's luminal geometry. The anchor thus fits within the luminal geometry to remain in a desired fixed position for implantation of the anchor and any stent-graft coupled to the anchor. The anchor is most preferably formed with two walls having a void therebetween which can be filled with fixation media to further secure the anchor at the desired implantation site. A lumen shaper balloon and delivery catheter are also disclosed for proper delivery, expansion and inflation of the positioning anchor and stent-graft elements according to this invention.Type: GrantFiled: October 22, 2007Date of Patent: August 25, 2015Assignee: Nellix, Inc.Inventors: Charles S. Taylor, Christopher Zarins, Robert A. Geshlider, Dwight P. Morejohn, Peter Johansson, Susan W. Vican, James T. McKinley
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Publication number: 20080039923Abstract: A positioning anchor is provided for a stent-graft for implantation to treat a damaged body lumen. The positioning anchor is generally tubular surrounding a primary fluid conduit. Arms extend laterally from the generally tubular structure of the anchor surrounding lateral fluid conduits. The form of these arms is preferably custom configured to match a particular patient's luminal geometry. The anchor thus fits within the luminal geometry to remain in a desired fixed position for implantation of the anchor and any stent-graft coupled to the anchor. The anchor is most preferably formed with two walls having a void therebetween which can be filled with fixation media to further secure the anchor at the desired implantation site. A lumen shaper balloon and delivery catheter are also disclosed for proper delivery, expansion and inflation of the positioning anchor and stent-graft elements according to this invention.Type: ApplicationFiled: October 22, 2007Publication date: February 14, 2008Applicant: Nellix, Inc.Inventors: Charles Taylor, Christopher Zarins, Robert Geshlider, Dwight Morejohn, Peter Johansson, Sue Vican, James McKinley
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Publication number: 20070238169Abstract: Methods and apparatus are provided for culturing cells under conditions for determining cellular differentiation and for separating cells from culture media based on differentiation. The apparatus comprises a bioreactor, media reservoir, a magnetic cell separator, an inlet port for adding magnetic particles to the bioreactor, and a circulating pump, wherein the bioreactor, media reservoir, magnetic cell separator and inlet port are on a single fluid circuit. The present method and apparatus provides a method for separating cells from culture without removing the cells from culture, so that un-selected cells may be returned to the bioreactor for further culture. The method employs magnetic labeling in culture, where the magnetic label specifically identifies cells to be distinguished, either by separation or retention in the culture. The method and apparatus are further designed to comprise means for electromechanical stimulation of hum embryonic stem cells for preparation of electrically responsive tissue.Type: ApplicationFiled: April 5, 2007Publication date: October 11, 2007Inventors: Oscar Abilez, Peyman Benharash, Christopher Zarins
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Publication number: 20040116997Abstract: A positioning anchor is provided for a stent-graft for implantation to treat a damaged body lumen. The positioning anchor is generally tubular surrounding a primary fluid conduit. Arms extend laterally from the generally tubular structure of the anchor surrounding lateral fluid conduits. The form of these arms is preferably custom configured to match a particular patient's luminal geometry. The anchor thus fits within the luminal geometry to remain in a desired fixed position for implantation of the anchor and any stent-graft coupled to the anchor. The anchor is most preferably formed with two walls having a void therebetween which can be filled with fixation media to further secure the anchor at the desired implantation site. A lumen shaper balloon and delivery catheter are also disclosed for proper delivery, expansion and inflation of the positioning anchor and stent-graft elements according to this invention.Type: ApplicationFiled: September 22, 2003Publication date: June 17, 2004Inventors: Charles S. Taylor, Christopher Zarins, Robert A. Geshlider, Dwight P. Morejohn, Peter Johansson, Sue W. Vican, James T. McKinley