Patents by Inventor Christos Cladaras

Christos Cladaras has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Isolated ApoA-I gene regulatory sequence elements
    Patent number: 5877009
    Abstract: The present invention provides isolated apolipoprotein transcription factors and gene regulatory elements. The invention also provides methods of modulating apolipoprotein gene expression by interfering with interactions between apolipoprotein transcription factors and their cognate regulatory elements and/or by interfering with protein-protein interactions between or among apolipoprotein transcription factors or between an apolipoprotein transcription factor and the transcription machinery. This invention has application in the treatment of disorders relating to lipid metabolism (e.g. atherosclerosis, hypertriglyceridemia, etc.).
    Type: Grant
    Filed: December 28, 1993
    Date of Patent: March 2, 1999
    Assignee: Trustees of Boston University
    Inventors: Vassilis I. Zannis, Christos Cladaras