Patents by Inventor Christy A. Lancaster
Christy A. Lancaster has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8947510Abstract: A method for 3D imaging of a biologic object (1) in an optical tomography system where a subcellular structure of a biological object (1) is labeled by introducing at least one nanoparticle-biomarker. The labeled biological object (1) is moved relatively to a microscope objective (62) to present varying angles of view and the labeled biological object (1) is illuminated with radiation having wavelengths between 150 nm and 900 nm. Radiation transmitted through the labeled biological object (1) and the microscope objective (62) within at least one wavelength bands is sensed with a color camera, or with a set of at least four monochrome cameras. A plurality of cross-sectional images of the biological object (1) from the sensed radiation is formed and reconstructed to make a 3D image of the labeled biological object (1).Type: GrantFiled: June 8, 2009Date of Patent: February 3, 2015Assignee: Visiongate, Inc.Inventors: Michael G. Meyer, J. Richard Rahn, Anna V. Tourovskaia, Julia Oi Yan Yu, Christy A Lancaster, Thomas Neumann, Mark E. Fauver
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Publication number: 20140370581Abstract: The present invention relates to microfluidic devices and methods for manipulating and analyzing fluid samples. The disclosed microfluidic devices utilize a plurality of microfluidic channels, inlets, valves, filter, pumps, liquid barriers and other elements arranged in various configurations to manipulate the flow of a fluid sample in order to prepare such sample for analysis.Type: ApplicationFiled: February 14, 2014Publication date: December 18, 2014Applicant: Micronics, Inc.Inventors: Patrick Saltsman, Mingchao Shen, Jeffrey M. Houkal, Christy A. Lancaster, C. Frederick Battrell, Bernhard H. Weigl
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Patent number: 8697009Abstract: The present invention relates to microfluidic devices and methods for manipulating and analyzing fluid samples. The disclosed microfluidic devices utilize a plurality of microfluidic channels, inlets, valves, filter, pumps, liquid barriers and other elements arranged in various configurations to manipulate the flow of a fluid sample in order to prepare such sample for analysis.Type: GrantFiled: September 6, 2013Date of Patent: April 15, 2014Assignee: Micronics, Inc.Inventors: Patrick Saltsman, Mingchao Shen, Jeffrey M. Houkal, Christy A. Lancaster, C. Frederick Battrell, Bernhard H. Weigl
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Publication number: 20140010736Abstract: The present invention relates to microfluidic devices and methods for manipulating and analyzing fluid samples. The disclosed microfluidic devices utilize a plurality of microfluidic channels, inlets, valves, filter, pumps, liquid barriers and other elements arranged in various configurations to manipulate the flow of a fluid sample in order to prepare such sample for analysis.Type: ApplicationFiled: September 6, 2013Publication date: January 9, 2014Applicant: Micronics, Inc.Inventors: Patrick Saltsman, Mingchao Shen, Jeffrey M. Houkal, Christy A. Lancaster, C. Frederick Battrell, Bernhard H. Weigl
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Patent number: 8557198Abstract: The present invention relates to microfluidic devices and methods for manipulating and analyzing fluid samples. The disclosed microfluidic devices utilize a plurality of microfluidic channels, inlets, valves, filter, pumps, liquid barriers and other elements arranged in various configurations to manipulate the flow of a fluid sample in order to prepare such sample for analysis.Type: GrantFiled: September 2, 2011Date of Patent: October 15, 2013Assignee: Micronics, Inc.Inventors: Patrick Saltsman, Mingchao Shen, Jeffrey M. Houkal, Christy A. Lancaster, C. Frederick Battrell, Bernhard H. Weigl
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Patent number: 8318109Abstract: The present invention relates to microfluidic devices and methods for manipulating and analyzing fluid samples. The disclosed microfluidic devices utilize a plurality of microfluidic channels, inlets, valves, filter, pumps, liquid barriers and other elements arranged in various configurations to manipulate the flow of a fluid sample in order to prepare such sample for analysis.Type: GrantFiled: January 11, 2010Date of Patent: November 27, 2012Assignee: Micronics, Inc.Inventors: Patrick Saltsman, Mingchao Shen, Jeffrey M. Houkal, Christy A. Lancaster, C. Frederick Battrell, Bernhard H. Weigl
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Publication number: 20120105600Abstract: A method for 3D imaging of a biologic object (1) in an optical tomography system where a subcellular structure of a biological object (1) is labeled by introducing at least one nanoparticle-biomarker. The labeled biological object (1) is moved relatively to a microscope objective (62) to present varying angles of view and the labeled biological object (1) is illuminated with radiation having wavelengths between 150 nm and 900 nm. Radiation transmitted through the labeled biological object (1) and the microscope objective (62) within at least one wavelength bands is sensed with a color camera, or with a set of at least four monochrome cameras. A plurality of cross-sectional images of the biological object (1) from the sensed radiation is formed and reconstructed to make a 3D image of the labeled biological object (1).Type: ApplicationFiled: June 8, 2009Publication date: May 3, 2012Inventors: Michael G. Meyer, J. Richard Rahn, Anna V. Tourovskaia, Julia Oi Yan Yu, Christy A. Lancaster, Thomas Neumann, Mark E. Fauver
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Publication number: 20120064612Abstract: The present invention relates to microfluidic devices and methods for manipulating and analyzing fluid samples. The disclosed microfluidic devices utilize a plurality of microfluidic channels, inlets, valves, filter, pumps, liquid barriers and other elements arranged in various configurations to manipulate the flow of a fluid sample in order to prepare such sample for analysis.Type: ApplicationFiled: September 2, 2011Publication date: March 15, 2012Applicant: Micronics, Inc.Inventors: Patrick Saltsman, Mingchao Shen, Jeffrey M. Houkal, Christy A. Lancaster, C. Frederick Battrell, Bernhard H. Weigl
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Publication number: 20100173395Abstract: The present invention relates to microfluidic devices and methods for manipulating and analyzing fluid samples. The disclosed microfluidic devices utilize a plurality of microfluidic channels, inlets, valves, filter, pumps, liquid barriers and other elements arranged in various configurations to manipulate the flow of a fluid sample in order to prepare such sample for analysis.Type: ApplicationFiled: January 11, 2010Publication date: July 8, 2010Applicant: Micronics, Inc.Inventors: Patrick Saltsman, Mingchao Shen, Jeffrey M. Houkal, Christy A. Lancaster, C. Frederick Battrell, Bernhard H. Weigl
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Patent number: 7648835Abstract: An integrated heat exchange system on a microfluidic card. According to one aspect of the invention, the portable microfluidic card has a heating, cooling and heat cycling system on-board such that the card can be used portably. The microfluidic card includes one or more reservoirs containing exothermic or endothermic material. Once the chemical process of the reservoir material is activated, the reservoir provides heat or cooling to specific locations of the microfluidic card. Multiple reservoirs may be included on a single card to provide varying temperatures. The assay chemicals can be moved to the various reservoirs to create a thermal cycle useful in many biological reactions, for example, Polymerase Chain Reaction (PCR) or rtPCR.Type: GrantFiled: August 27, 2008Date of Patent: January 19, 2010Assignee: Micronics, Inc.Inventors: Wayne L. Breidford, Christy A. Lancaster, Jon W. Hayenga, Ronald L. Bardell, Jeffrey F. Tonn, Bernhard H. Weigl
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Publication number: 20090325276Abstract: Combinations of microfluidic diagnostic testing modules for simultaneous evaluations of serological and molecular biological targets are provided, and include panel testing for both antibodies (or antigens) and nucleic acid targets in one single-use device. These improvements are directed to evaluating the overall progress and activity of a pathogenic process in real time, at the point of care, not merely the presence or absence of a particular diagnostic marker, which can often be incomplete or misleading.Type: ApplicationFiled: March 25, 2009Publication date: December 31, 2009Applicant: Micronics, Inc.Inventors: C. Frederick Battrell, John Gerdes, Wayne L. Breidford, Jason Capodanno, Stephen Mordue, John Clemmens, Denise Maxine Hoekstra, Christy A. Lancaster, John R. Williford, Patrick Maloney, Joan Haab
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Patent number: 7544506Abstract: An integrated heat exchange system on a microfluidic card. According to one aspect of the invention, the portable microfluidic card has a heating, cooling and heat cycling system on-board such that the card can be used portably. The microfluidic card includes one or more reservoirs containing exothermic or endothermic material. Once the chemical process of the reservoir material is activated, the reservoir provides heat or cooling to specific locations of the microfluidic card. Multiple reservoirs may be included on a single card to provide varying temperatures. The assay chemicals can be moved to the various reservoirs to create a thermal cycle useful in many biological reactions, for example, Polymerase Chain Reaction (PCR) or rtPCR.Type: GrantFiled: June 7, 2004Date of Patent: June 9, 2009Assignee: Micronics, Inc.Inventors: Wayne Breidford, Christy A Lancaster, Jon Wallace Hayenga, Ronald L Bardell, Jeffrey F Tonn, Bernhard H Weigl
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Publication number: 20090081771Abstract: An integrated heat exchange system on a microfluidic card. According to one aspect of the invention, the portable microfluidic card has a heating, cooling and heat cycling system on-board such that the card can be used portably. The microfluidic card includes one or more reservoirs containing exothermic or endothermic material. Once the chemical process of the reservoir material is activated, the reservoir provides heat or cooling to specific locations of the microfluidic card. Multiple reservoirs may be included on a single card to provide varying temperatures. The assay chemicals can be moved to the various reservoirs to create a thermal cycle useful in many biological reactions, for example, Polymerase Chain Reaction (PCR) or rtPCR.Type: ApplicationFiled: August 27, 2008Publication date: March 26, 2009Applicant: Micronics, Inc.Inventors: Wayne L. Breidford, Christy A. Lancaster, Jon W. Hayenga, Ronald L. Bardell, Jeffrey F. Tonn, Bernhard H. Weigl
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Publication number: 20090022624Abstract: The present invention relates to microfluidic devices and methods for manipulating and analyzing fluid samples. The disclosed microfluidic devices utilize a plurality of microfluidic channels, inlets, valves, filter, pumps, liquid barriers and other elements arranged in various configurations to manipulate the flow of a fluid sample in order to prepare such sample for analysis.Type: ApplicationFiled: July 30, 2008Publication date: January 22, 2009Applicant: Micronics, Inc.Inventors: Patrick Saltsman, Mingchao Shen, Jeffrey M. Houkal, Christy A. Lancaster, C. Frederick Battrell, Bernhard H. Weigl
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Patent number: 7419638Abstract: The present invention relates to microfluidic devices and methods for manipulating and analyzing fluid samples. The disclosed microfluidic devices utilize a plurality of microfluidic channels, inlets, valves, filter, pumps, liquid barriers and other elements arranged in various configurations to manipulate the flow of a fluid sample in order to prepare such sample for analysis.Type: GrantFiled: June 17, 2004Date of Patent: September 2, 2008Assignee: Micronics, Inc.Inventors: Patrick Saltsman, Mingchao Shen, Jeffrey M Houkal, Christy A Lancaster, C. Frederick Battrell, Bernhard H Weigl
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Patent number: 7416892Abstract: A microfluidic system for isolation and amplification of DNA or RNA from aqueous solutions and detection of the DNA or RNA on a lateral flow detection strip, including a disposable microfluidic card for use in analysis of bacteria in platelets and an analysis of sexually transmitted diseases (STD) in urine. The card will include an embedded membrane that filters out cells and cellular debris. Any biological debris on the membrane will be lysed and the DNA or RNA amplified via PCR amplification protocol, including appropriate reagents and thermal cycling conditions. The amplified DNA or RNA are transferred to a lateral flow detection strip for a visual diagnostic read out. An alternate embodiment includes a microfluidic card for use in typing antiglobulin assays.Type: GrantFiled: January 21, 2004Date of Patent: August 26, 2008Assignee: Micronics, Inc.Inventors: C. Frederick Battrell, Mingchao Shen, Bernhard H. Weigl, Jeffrey M. Houkal, Christy A. Lancaster, Wayne Breidford
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Publication number: 20060246575Abstract: The present invention relates to microfluidic devices and methods for detecting rare cells. The disclosed microfluidic devices and methods integrate and automate sample preparation, cell labeling, cell sorting and enrichment, and DNA/RNA analysis of sorted cells.Type: ApplicationFiled: January 13, 2006Publication date: November 2, 2006Applicant: Micronics, Inc.Inventors: Christy Lancaster, C. Battrell, Jason Capodanno, John Gerdes, Mark Kokoris, Melud Nabavi, Stephen Mordue, Robert McRuer, John Clemmens, Wayne Breidford
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Publication number: 20050129582Abstract: An integrated heat exchange system on a microfluidic card. According to one aspect of the invention, the portable microfluidic card has a heating, cooling and heat cycling system on-board such that the card can be used portably. The microfluidic card includes one or more reservoirs containing exothermic or endothermic material. Once the chemical process of the reservoir material is activated, the reservoir provides heat or cooling to specific locations of the microfluidic card. Multiple reservoirs may be included on a single card to provide varying temperatures. The assay chemicals can be moved to the various reservoirs to create a thermal cycle useful in many biological reactions, for example, Polymerase Chain Reaction (PCR) or rtPCR.Type: ApplicationFiled: June 7, 2004Publication date: June 16, 2005Applicant: Micronics, Inc.Inventors: Wayne Breidford, Christy Lancaster, Jon Hayenga, Ronald Bardell, Jeffrey Tonn, Bernhard Weigl
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Publication number: 20050106066Abstract: The present invention relates to microfluidic devices and methods for manipulating and analyzing fluid samples. The disclosed microfluidic devices utilize a plurality of microfluidic channels, inlets, valves, filter, pumps, liquid barriers and other elements arranged in various configurations to manipulate the flow of a fluid sample in order to prepare such sample for analysis.Type: ApplicationFiled: June 17, 2004Publication date: May 19, 2005Applicant: Micronics, Inc.Inventors: Patrick Saltsman, Mingchao Shen, Jeffrey Houkal, Christy Lancaster, C. Battrell, Bernhard Weigl
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Publication number: 20050013732Abstract: A microfluidic system for isolation and amplification of DNA or RNA from aqueous solutions and detection of the DNA or RNA on a lateral flow detection strip, including a disposable microfluidic card for use in analysis of bacteria in platelets and an analysis of sexually transmitted diseases (STD) in urine. The card will include an embedded membrane that filters out cells and cellular debris. Any biological debris on the membrane will be lysed and the DNA or RNA amplified via PCR amplification protocol, including appropriate reagents and thermal cycling conditions. The amplified DNA or RNA are transferred to a lateral flow detection strip for a visual diagnostic read out. An alternate embodiment includes a microfluidic card for use in typing antiglobulin assays.Type: ApplicationFiled: January 21, 2004Publication date: January 20, 2005Applicant: Micronics, Inc.Inventors: C. Battrell, Mingchao Shen, Bernhard Weigl, Jeffrey Houkal, Christy Lancaster, Wayne Breidford