Patents by Inventor Christy L. Haynes

Christy L. Haynes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • LINEAR POLYMER AFFINITY AGENT SENSOR FOR SURFACE-ENHANCED RAMAN SPECTROSCOPY AND METHOD USING THE SAME
    Publication number: 20220136973
    Abstract: Methods and systems related to a linear polymer affinity agent sensor for SERS are disclosed. Use of the sensor may include mixing a linear polymer affinity agent in a sample solution, subjecting a metal substrate to the sample solution to attach the linear polymer affinity agent to the metal substrate, generating, via Raman Spectroscopy, spectral data representing the at least one linear polymer affinity agent attached to the metal substrate, and determining whether two or more analytes are present in the solution at respective minimum threshold concentrations based on the spectral data.
    Type: Application
    Filed: October 29, 2021
    Publication date: May 5, 2022
    Inventors: Rebeca S. Rodriguez, Victoria M. Szlag, Theresa M. Reineke, Christy L. Haynes
  • Mesoporous silica-coated nanoparticles
    Patent number: 10493098
    Abstract: The present invention relates to mesoporous silica coated nanoparticles comprising a metal oxide nanoparticle core; and a mesoporous silica shell encapsulating metal oxide core; wherein said mesoporous silica shell and the metal oxide core are not in full contact. The nanoparticles of the invention are useful as diagnostic and therapeutic agents.
    Type: Grant
    Filed: July 28, 2015
    Date of Patent: December 3, 2019
    Assignee: Regents of the University of Minnesota
    Inventors: Christy L. Haynes, Katherine Rose Hurley, Samuel Michael Egger
  • GLYCOPOLYMER CAPTURE MATRIX FOR USE WITH SURFACE-ENHANCED RAMAN SPECTROSCOPY DETECTION AND RELATED SYSTEMS AND METHODS
    Publication number: 20170328912
    Abstract: A method of making a sensor includes subjecting a metal substrate to a solution having glycopolymer chains and attaching the glycopolymer chains to the metal substrate to form a glycopolymer-functionalized metal substrate that can bind a lectin target. A lectin target can be a food allergen or a toxin. The metal substrate can include a plasmonic metal. A method of using the sensor includes incubating a portion of the sensor in a sample fluid and another portion of the sensor in a control fluid. Spectral data sets are generated via Raman Spectroscopy for each portion of the sensor. The presence and concentration of a lectin target in the sample fluid is determined by comparing the spectral data sets.
    Type: Application
    Filed: May 10, 2017
    Publication date: November 16, 2017
    Inventors: Victoria Marie Szlag, Christy L. Haynes, Theresa Reineke, Antonio Campos, Bharat Wagh
  • MESOPOROUS SILICA-COATED NANOPARTICLES
    Publication number: 20160051471
    Abstract: The present invention relates to mesoporous silica coated nanoparticles comprising a metal oxide nanoparticle core; and a mesoporous silica shell encapsulating metal oxide core; wherein said mesoporous silica shell and the metal oxide core are not in full contact. The nanoparticles of the invention are useful as diagnostic and therapeutic agents.
    Type: Application
    Filed: July 28, 2015
    Publication date: February 25, 2016
    Inventors: Christy L. Haynes, Katherine Rose Hurley, Sam M. Egger
  • Surface-enhanced raman nanobiosensor
    Patent number: 8592226
    Abstract: The present invention relates to biosensors, in particular to surface-enhanced Raman biosensors for detection of in vivo and ex vivo analytes. In particular, the present invention provides compositions and methods for the in vivo detection of analytes such as glucose.
    Type: Grant
    Filed: September 9, 2009
    Date of Patent: November 26, 2013
    Assignee: Northwestern University
    Inventors: Richard P. Van Duyne, Mathew R. Glucksberg, Karen E. Peltier, Christy L. Haynes, Joseph T. Walsh, Chanda Ranjit Yonzon, Nilam C. Shah, Olga Lyandres, Douglas A. Stuart, Jonathan M. Yuen
  • SURFACE-ENHANCED RAMAN NANOBIOSENSOR
    Publication number: 20100087723
    Abstract: The present invention relates to biosensors, in particular to surface-enhanced Raman biosensors for detection of in vivo and ex vivo analytes. In particular, the present invention provides compositions and methods for the in vivo detection of analytes such as glucose.
    Type: Application
    Filed: September 9, 2009
    Publication date: April 8, 2010
    Inventors: Richard P. Van Duyne, Mathew R. Glucksberg, Karen E. Peltier, Christy L. Haynes, Joseph T. Walsh, Chanda Ranjit Yonzon, Nilam C. Shah, Olga Lyandres, Douglas A. Stuart, Jonathan M. Yuen
  • Surface-enhanced raman nanobiosensor
    Publication number: 20090118605
    Abstract: The present invention relates to biosensors, in particular to surface-enhanced Raman biosensors for detection of in vivo and ex vivo analytes. In particular, the present invention provides compositions and methods for the in vivo detection of analytes such as glucose.
    Type: Application
    Filed: March 1, 2006
    Publication date: May 7, 2009
    Applicant: Northwestern University
    Inventors: Richard P. Van Duyne, Matthew R. Glucksberg, Karen E. Pettier, Christy L. Haynes, Joseph T. Walsh, Chanda Ranjit Yonzon, Nilam C. Shah, Olga Lyandres, Douglas A. Stuart, Jonathan M. Yuen
  • Surface-enhanced raman nanobiosensor
    Publication number: 20040180379
    Abstract: The present invention relates to biosensors, in particular to surface-enhanced Raman biosensors for detection of intracellular analytes. In particular, the present invention provides compositions and methods for the in vivo detection of analytes such as glucose.
    Type: Application
    Filed: August 29, 2003
    Publication date: September 16, 2004
    Applicant: Northwestern University
    Inventors: Richard P. Van Duyne, Matthew R. Glucksberg, Karen Shafer-Peltier, Christy L. Haynes, Joseph Walsh