Patents by Inventor Chu Chun Hsueh

Chu Chun Hsueh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8420119
    Abstract: This present disclosure relates to pharmaceutical compositions for treating tumors using a polymeric micelle encapsulating an anti-tumor drug. The polymeric micelle comprises block copolymers comprising at least one hydrophilic block, at least one hydrophobic block, and at least one zwitterion. The present disclosure also relates to methods of enhancing the solubility of such drugs, methods of increasing the blood circulating time of such drugs, and methods of delivering such drugs to one or more solid tumors.
    Type: Grant
    Filed: August 20, 2009
    Date of Patent: April 16, 2013
    Assignee: Industrial Technology Research Institute
    Inventors: Yuan-Hung Hsu, Chu-Chun Hsueh, Yuan-Chia Chang, Jui-Mei Lu, Pei Kan
  • Publication number: 20120100220
    Abstract: This present disclosure relates to pharmaceutical compositions for treating tumors using a polymeric micelle encapsulating an anti-tumor drug. The polymeric micelle comprises block copolymers comprising at least one hydrophilic block, at least one hydrophobic block, and at least one zwitterion. The present disclosure also relates to methods of enhancing the solubility of such drugs, methods of increasing the blood circulating time of such drugs, and methods of delivering such drugs to one or more solid tumors.
    Type: Application
    Filed: August 20, 2009
    Publication date: April 26, 2012
    Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Yuan-Hung Hsu, Chu-Chun Hsueh, Yuan-Chia Chang, Jui-Mei Lu, Pei Kan
  • Publication number: 20080161594
    Abstract: A method employs the addition of additive to increase the solubility of active ingredients in solution. Furthermore, a nanoparticle apparatus that uses inkjet dispenser is utilized to fabricate nanoparticles. The method comprises: (a) mixing a fenofibrate substance, an organic solvent and a solubility enhancing additive to form a saturated solution; and (b) spray-drying the saturated solution to form the nanoparticles containing fenofibrate, wherein the solubility enhancing additive comprises a surfactant or an excipient.
    Type: Application
    Filed: December 29, 2006
    Publication date: July 3, 2008
    Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: John Jianghann Lin, Chu Chun Hsueh, Pei Kan, Po-Fu Chou, En-Wei Chang, Wei-Liang Hsu