Patents by Inventor Chuanke CHAI

Chuanke CHAI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • DEUTERATED 2-ARYLHETEROCYCLE-3-OXO-2,3- DIHYDROPYRIDAZINE-4-CARBOXAMIDE INHIBITOR AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF
    Publication number: 20240002362
    Abstract: The present invention relates to a deuterated 3-oxo-2,3-dihydropyridazine-4-carboxamide inhibitor, a preparation method therefor, and an application thereof. Specifically, the compound of the present invention has the structure shown in formula (I); also disclosed in the present invention are a preparation method for said compound and the use thereof as an AhR inhibitor; the compound of the present invention has a good selective inhibitory effect on AhR, and has better pharmacodynamics, pharmacokinetic properties, and lower toxic and side effects.
    Type: Application
    Filed: November 29, 2021
    Publication date: January 4, 2024
    Inventors: Binhua LV, Dawei CUI, Lianjun LIU, Xudong PANG, Chuanke CHAI
  • IMIDAZOQUINOLINE SUBSTITUTED PHOSPHORIC ESTER AGONIST, AND PREPARATION THEREFOR AND APPLICATION THEREOF
    Publication number: 20230008368
    Abstract: The present invention relates to an imidazoquinoline substituted phosphoric ester agonist, and a preparation therefor and an application thereof. Specifically, the compounds of the present invention have the structure shown in formula (I), wherein the definition of each group and substituent is as described in the description. Also disclosed in the present invention are a preparation method for the compound and use thereof as a TLR agonist.
    Type: Application
    Filed: November 11, 2020
    Publication date: January 12, 2023
    Inventors: Binhua LV, Dawei CUI, Chuanke CHAI, Ruifeng LIU, Zelin SHENG