Patents by Inventor Chubing Tan

Chubing Tan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Stable antibody-drug conjugate, preparation method therefor, and use thereof
    Patent number: 11911434
    Abstract: The present invention provides a conjugate and preparation method thereof, a pharmaceutical composition comprising the conjugate and use of the pharmaceutical composition in the manufacture of a medicament for the treatment or prevention of a disease.
    Type: Grant
    Filed: February 19, 2021
    Date of Patent: February 27, 2024
    Assignee: GENEQUANTUM HEALTHCARE (SUZHOU) CO., LTD.
    Inventors: Gang Qin, Jinduo Yuan, Lu Jiang, Chubing Tan, Lili Shi, Cao Lv, Leilei Chen
  • Stable antibody-drug conjugate, preparation method therefor, and use thereof
    Patent number: 11911435
    Abstract: A conjugate and preparation method therefor, comprising a medication composition comprising the conjugate and a use of the medication composition in preparing medications for the treatment or prevention of diseases.
    Type: Grant
    Filed: February 19, 2021
    Date of Patent: February 27, 2024
    Assignee: GENEQUANTUM HEALTHCARE (SUZHOU) CO., LTD.
    Inventors: Gang Qin, Jinduo Yuan, Lu Jiang, Chubing Tan, Lili Shi, Cao Lv, Leilei Chen
  • STABLE ANTIBODY-DRUG CONJUGATE, PREPARATION METHOD THEREFOR, AND USE THEREOF
    Publication number: 20210401924
    Abstract: The present invention provides a conjugate and preparation method thereof, a pharmaceutical composition comprising the conjugate and use of the pharmaceutical composition in the manufacture of a medicament for the treatment or prevention of a disease.
    Type: Application
    Filed: February 19, 2021
    Publication date: December 30, 2021
    Inventors: Gang Qin, Jinduo Yuan, Lu Jiang, Chubing Tan, Lili Shi, Cao Lv, Leilei Chen
  • Stable antibody-drug conjugate, preparation method therefor, and use thereof
    Patent number: 11040084
    Abstract: The present invention provides a conjugate and preparation method thereof, a pharmaceutical composition comprising the conjugate and use of the pharmaceutical composition in the manufacture of a medicament for the treatment or prevention of a disease.
    Type: Grant
    Filed: April 29, 2015
    Date of Patent: June 22, 2021
    Assignee: GENEQUANTUM HEALTHCARE (SUZHOU) CO., LTD.
    Inventors: Gang Qin, Jinduo Yuan, Lu Jiang, Chubing Tan, Lili Shi, Cao Lv, Leilei Chen
  • NEW STABLE ANTIBODY-DRUG CONJUGATE, PREPARATION METHOD THEREFOR, AND USE THEREOF
    Publication number: 20210177929
    Abstract: A conjugate and preparation method therefor, comprising a medication composition comprising the conjugate and a use of the medication composition in preparing medications for the treatment or prevention of diseases.
    Type: Application
    Filed: February 19, 2021
    Publication date: June 17, 2021
    Applicant: GENEQUANTUM HEALTHCARE (SUZHOU) CO., LTD.
    Inventors: Gang Qin, Jinduo Yuan, Lu Jiang, Chubing Tan, Lili Shi, Cao Lv, Leilei Chen
  • STABLE ANTIBODY-DRUG CONJUGATE, PREPARATION METHOD THEREFOR, AND USE THEREOF
    Publication number: 20170112944
    Abstract: The present invention provides a conjugate and preparation method thereof, a pharmaceutical composition comprising the conjugate and use of the pharmaceutical composition in the manufacture of a medicament for the treatment or prevention of a disease.
    Type: Application
    Filed: April 29, 2015
    Publication date: April 27, 2017
    Inventors: Gang Qin, Jinduo Yuan, Lu Jiang, Chubing Tan, Lili Shi, Cao Lv, Leilei Chen
  • Phenyl C-glucoside derivatives, preparation methods and uses thereof
    Patent number: 9062087
    Abstract: The present invention relates to a sodium glucose cotransporter 2 (SGLT2) inhibitor with a phenyl C-glucoside structure, its preparation method, a pharmaceutical composition containing the same, and its use in treating diabetes and preparing an anti-diabetes medicament. The invention provides a compound with the structure of general formula I and a pharmaceutically acceptable salt and prodrug ester thereof, wherein, the definitions of R5 and R6 are selected from the following: (1) R5=R6=Me; (2) R5=Me, R6=OMe; (3) R5=Me, R6=H; (4) R5=Me, R6=F; (5) R5=F, R6=H; and (6) R5=OMe, R6=H.
    Type: Grant
    Filed: January 14, 2011
    Date of Patent: June 23, 2015
    Assignee: Tianjin Institute of Pharmaceutical Research
    Inventors: Guilong Zhao, Hua Shao, Weiren Xu, Wei Liu, Yuli Wang, Lida Tang, Chubing Tan, Bingni Liu, Shijun Zhang
  • Thienopyridine ester derivative containing cyano group, preparation method, use and composition thereof
    Patent number: 8809366
    Abstract: A compound with the structure of the formula (I) or a pharmaceutically acceptable salt, a preparation method and use thereof are disclosed in the present invention, wherein R is cyano group. The compound provided by the present invention has an antiplatelet aggregation activity and can be used in preparing a medicament for preventing or treating cardiac and cerebral vascular diseases such as coronary artery syndromes, myocardial infarction and myocardial ischemia which are caused by platelet aggregation.
    Type: Grant
    Filed: November 12, 2012
    Date of Patent: August 19, 2014
    Assignee: Tianjin Institute of Pharmaceutical Research
    Inventors: Dengke Liu, Ying Liu, Nan Yue, Furong Chen, Chubing Tan, Yunsong Zhou, Peng Liu, Yigui Zhao, Deguang Zhi, Mo Liu, Bingni Liu, Changjiang Huang, Lida Tang
  • Amide thiazole derivative, preparation method and uses thereof
    Patent number: 8481577
    Abstract: The present invention relates to the field of drugs associated with treating diabetes. Particularly, the present invention relates to a dipeptidyl peptidase-IV inhibitor having the structure shown by formula (I), which contains amide thiazole structure and has an effect on treating diabetes, and a preparation method and a pharmaceutical composition containing it, as well as use thereof in manufacture of the drugs for treating the diabetes, wherein, R1 is methyl; R2 is phenyl; phenyl, 2-thienyl substituted in a mono-substituted, bi-substituted manner by fluorine and methyl.
    Type: Grant
    Filed: June 16, 2011
    Date of Patent: July 9, 2013
    Assignee: Tianjin Institute of Pharmaceutical Research
    Inventors: Guilong Zhao, Weiren Xu, Yuli Wang, Lida Tang, Yiliang Li, Meixiang Zou, Wei Liu, Hua Shao, Chubing Tan, Peng Liu
  • PHENYL C-GLUCOSIDE DERIVATIVES, PREPARATION METHODS AND USES THEREOF
    Publication number: 20130023486
    Abstract: The present invention relates to a sodium glucose cotransporter 2 (SGLT2) inhibitor with a phenyl C-glucoside structure, its preparation method, a pharmaceutical composition containing the same, and its use in treating diabetes and preparing an anti-diabetes medicament. The invention provides a compound with the structure of general formula I and a pharmaceutically acceptable salt and prodrug ester thereof, wherein, the definitions of R5 and R6 are selected from the following: (1) R5=R6=Me; (2) R5=Me, R6=OMe; (3) R5=Me, R6=H; (4) R5=Me, R6=F; (5) R5=F, R6=H; and (6) R5=OMe, R6=H.
    Type: Application
    Filed: January 14, 2011
    Publication date: January 24, 2013
    Applicant: TIANJIN INSTITUTE OF PHARMACEUTICAL RESEARCH
    Inventors: Guilong Zhao, Hua Shao, Weiren Xu, Wei Liu, Yuli Wang, Lida Tang, Chubing Tan, Bingni Liu, Shijun Zhang
  • AMIDE THIAZOLE DERIVATIVE, PREPARATION METHOD AND USES THEREOF
    Publication number: 20110281922
    Abstract: The present invention relates to the field of drugs associated with treating diabetes. Particularly, the present invention relates to a dipeptidyl peptidase-IV inhibitor having the structure shown by formula (I), which contains amide thiazole structure and has an effect on treating diabetes, and a preparation method and a pharmaceutical composition containing it, as well as use thereof in manufacture of the drugs for treating the diabetes, wherein, R1 is methyl; R2 is phenyl; phenyl, 2-thienyl substituted in a mono-substituted, bi-substituted manner by fluorine and methyl.
    Type: Application
    Filed: June 16, 2011
    Publication date: November 17, 2011
    Applicant: TIANJIN INSTITUTE OF PHARMACEUTICAL RESEARCH
    Inventors: Guilong ZHAO, Weiren Xu, Yuli Wang, Lida Tang, Yiliang Li, Meixiang Zou, Wei Liu, Hua Shao, Chubing Tan, Peng Liu