Abstract: Systems, methods, and computer-readable media are disclosed for determining whether a portion of an auto-generated prescription product order is eligible for replenishment at a reduced price, such as a 340B price, and if so determined, partitioning the order to replenish the portion of the order at the reduced price. The number of 340B accumulations accrued by a contract pharmacy on behalf of a covered entity may be determined, and a prescription product order may be partitioned into an order for those items that can be replenished at the 340B price based on the number of 340B accumulations and an order for the remaining items purchased at a higher price such as a WAC price.