Patents by Inventor Chuen-Yuan Hsu

Chuen-Yuan Hsu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200230595
    Abstract: An immunodetection method is provided, including: providing a disk; providing a capture antibody on a substrate adding a sample to a reservoir; applying a first rotational speed to transfer the sample containing an antigen from the reservoir to a reaction chamber applying a second rotational speed to precipitate the sample on the substrate so as to combine the antigen in the sample with the capture antibody to obtain a first complex; using capillary force to make the sample flow out of the reaction chamber and to fill the flow channel; applying a third rotational speed to transfer the sample from the flow channel to the waste chamber; providing a detection antibody on the substrate to combine the detection antibody with the first complex to obtain a second complex; and detecting a spectral signal from the localized surface plasma resonance of the second complex.
    Type: Application
    Filed: January 9, 2020
    Publication date: July 23, 2020
    Inventors: Chih-Hsin Shih, Ho-Chin Wu, Cheng-Liang Lee, Chuen-Yuan Hsu
  • Publication number: 20190391137
    Abstract: A method for manufacturing a measuring kit is disclosed. The method for manufacturing a measuring kit includes steps of providing a carrier including a substrate having a surface; coating a silane onto the surface of the substrate; providing an organic molecule; adding the organic molecule onto the carrier; outputting a microwave energy by a coaxial cable; and emitting the microwave energy through a radiator to microwave the carrier and the organic molecule uniformly to coat the organic molecule onto the carrier carrying the silane, wherein the measuring kit is used to apply an enzyme-linked immunosorbent assay.
    Type: Application
    Filed: September 9, 2019
    Publication date: December 26, 2019
    Inventors: Chuen-Yuan Hsu, Yi-Heui Hsieh, Chiao-Wen Huang
  • Publication number: 20190011444
    Abstract: A sensing method is disclosed. The sensing method includes steps of providing a carrier including a hole having a bottom, wherein a plurality of spaced apart first nanoparticles are disposed on the bottom; coating a sensing molecule in the hole; providing a testing solution having a testing parameter to the hole, wherein the testing solution has a complex including a testing molecule and a second nanoparticle, and a specific binding occurs between the testing molecule and the sensing molecule; centrifuging the carrier to subside the complex; washing the hole; and measuring a synthetic spectral signal change of the first nanoparticle and the second nanoparticle according to a degree of the specific binding between the testing molecule and the sensing molecule to determine the testing parameter of the testing solution.
    Type: Application
    Filed: March 8, 2018
    Publication date: January 10, 2019
    Inventors: Chuen-Yuan Hsu, Yi-Heui Hsieh, Chiao-Wen Huang, Ting Liu
  • Publication number: 20180267026
    Abstract: A method for manufacturing a measuring kit is disclosed. The method for manufacturing a measuring kit includes steps of providing a carrier including a substrate having a surface; coating a silane onto the surface of the substrate; providing an organic molecule; adding the organic molecule onto the carrier; outputting a microwave energy by a coaxial cable; and emitting the microwave energy through a radiator to microwave the carrier and the organic molecule uniformly to coat the organic molecule onto the carrier carrying the silane, wherein the measuring kit is used to apply an enzyme-linked immunosorbent assay.
    Type: Application
    Filed: March 13, 2018
    Publication date: September 20, 2018
    Inventors: Chuen-Yuan Hsu, Yi-Heui Hsieh, Chiao-Wen Huang
  • Publication number: 20160327554
    Abstract: A sensing chip for sensing a first organic molecule in a sample is disclosed. The sensing chip includes a substrate, wherein there are a plurality of separated nanometers on the substrate and a plurality of local substrate surfaces among the plurality of separated nanometers; a silane fixed on the plurality of local substrate surfaces; and a second organic molecule fixed on surfaces of the separated nanometers, wherein there is specificity between the second organic molecule and the first organic molecule.
    Type: Application
    Filed: May 6, 2016
    Publication date: November 10, 2016
    Inventors: Ying-Cheng Hung, Chuen-Yuan Hsu, Yi-Heui Hsieh, Chiao-Wen Huang
  • Patent number: 9091683
    Abstract: A method of fabricating a biosensor chip includes: forming at least one metallic layer on a transparent substrate to form a composite member; disposing the composite member in a vacuumed chamber, and introducing a gas into the vacuumed chamber; applying microwave energy to the gas to produce a microwave plasma of the gas within the vacuumed chamber, and causing the microwave plasma to interact with the metallic layer so that the metallic layer is melted and formed into a plurality of metallic nanoparticles that are spaced apart from each other and that expose partially the surface of the transparent substrate; and disposing a receptor at the surface of the transparent substrate that is exposed among the metallic nanoparticles. A biosensor chip is also disclosed.
    Type: Grant
    Filed: April 1, 2013
    Date of Patent: July 28, 2015
    Assignee: NATIONAL CHUNG-HSING UNIVERSITY
    Inventors: Kuan-Jiuh Lin, Chuen-Yuan Hsu
  • Publication number: 20150204865
    Abstract: A sensing method, comprising steps of causing a first molecule to be adjacent to one of a plurality of first nanoparticles spacedly disposed on a detachable chip; adding a target object to contact the first molecule; and measuring a spectral signal, wherein a variation of the spectral signal of the plurality of first nanoparticles occurs when the target object demonstrates a first specific binding with the first molecule.
    Type: Application
    Filed: January 21, 2015
    Publication date: July 23, 2015
    Applicant: SIWARD CRYSTAL TECHNOLOGY CO., LTD.
    Inventors: Kuan-Jiuh Lin, Chuen-Yuan Hsu, Wei-Hung Chen, Yi-Heui Hsieh, Yun-Ting Chiang, Jia Yu Chang
  • Patent number: 8697196
    Abstract: A method of forming a metal pattern comprises: (a) providing a substrate; (b) depositing at least one patterned metal layer which includes a metal selected from an inert metal, an inert metal alloy, and combinations thereof; (c) disposing the substrate and the patterned metal layer in a vacuum chamber, vacuuming the vacuum chamber, and introducing a gas into the vacuum chamber; and (d) applying microwave energy to the gas to produce a microwave plasma of the gas within the vacuum chamber so that the patterned metal layer is acted by the microwave plasma and formed into a plurality of spaced apart metal nanoparticles on the substrate.
    Type: Grant
    Filed: May 22, 2009
    Date of Patent: April 15, 2014
    Inventors: Kuan-Jiuh Lin, Chuen-Yuan Hsu
  • Patent number: 8663554
    Abstract: A method of fabricating a biosensor chip includes: forming at least one metallic layer on a transparent substrate to form a composite member; disposing the composite member in a vacuumed chamber, and introducing a gas into the vacuumed chamber; applying microwave energy to the gas to produce a microwave plasma of the gas within the vacuumed chamber, and causing the microwave plasma to interact with the metallic layer so that the metallic layer is melted and formed into a plurality of metallic nanoparticles that are spaced apart from each other and that expose partially the surface of the transparent substrate; and disposing a receptor at the surface of the transparent substrate that is exposed among the metallic nanoparticles. A biosensor chip is also disclosed.
    Type: Grant
    Filed: August 18, 2010
    Date of Patent: March 4, 2014
    Inventors: Kuan-Jiuh Lin, Chuen-Yuan Hsu
  • Publication number: 20130230427
    Abstract: A method of fabricating a biosensor chip includes: forming at least one metallic layer on a transparent substrate to form a composite member; disposing the composite member in a vacuumed chamber, and introducing a gas into the vacuumed chamber; applying microwave energy to the gas to produce a microwave plasma of the gas within the vacuumed chamber, and causing the microwave plasma to interact with the metallic layer so that the metallic layer is melted and formed into a plurality of metallic nanoparticles that are spaced apart from each other and that expose partially the surface of the transparent substrate; and disposing a receptor at the surface of the transparent substrate that is exposed among the metallic nanoparticles. A biosensor chip is also disclosed.
    Type: Application
    Filed: April 1, 2013
    Publication date: September 5, 2013
    Inventors: Kuan-Jiuh Lin, Chuen-Yuan Hsu
  • Publication number: 20120015164
    Abstract: A glass product includes a glass substrate, and a metallic nano-network layer embedded and continuously extending in the glass substrate. A method for producing the glass product is also disclosed.
    Type: Application
    Filed: July 14, 2011
    Publication date: January 19, 2012
    Inventors: Kuan-Jiuh Lin, Chuen-Yuan Hsu
  • Publication number: 20110044857
    Abstract: A method of fabricating a biosensor chip includes: forming at least one metallic layer on a transparent substrate to form a composite member; disposing the composite member in a vacuumed chamber, and introducing a gas into the vacuumed chamber; applying microwave energy to the gas to produce a microwave plasma of the gas within the vacuumed chamber, and causing the microwave plasma to interact with the metallic layer so that the metallic layer is melted and formed into a plurality of metallic nanoparticles that are spaced apart from each other and that expose partially the surface of the transparent substrate; and disposing a receptor at the surface of the transparent substrate that is exposed among the metallic nanoparticles. A biosensor chip is also disclosed.
    Type: Application
    Filed: August 18, 2010
    Publication date: February 24, 2011
    Inventors: Kuan-Jiuh Lin, Chuen-Yuan Hsu
  • Publication number: 20100206720
    Abstract: A method of producing inorganic nanoparticles includes: (a) providing a layered structure including a substrate and an inorganic layer; (b) disposing the layered structure in a vacuum chamber, vacuuming the vacuum chamber, and introducing a gas into the vacuum chamber; and (c) applying microwave energy to the gas to produce a microwave plasma of the gas within the vacuum chamber so that the inorganic layer is acted by the microwave plasma and formed into a plurality of inorganic nanoparticles on the substrate. A system for producing the nanoparticles is also disclosed.
    Type: Application
    Filed: May 22, 2009
    Publication date: August 19, 2010
    Inventors: Kuan-Jiuh Lin, Chuen-Yuan Hsu
  • Publication number: 20100209617
    Abstract: A method of forming a metal pattern comprises: (a) providing a substrate; (b) depositing at least one patterned metal layer which includes a metal selected from an inert metal, an inert metal alloy, and combinations thereof; (c) disposing the substrate and the patterned metal layer in a vacuum chamber, vacuuming the vacuum chamber, and introducing a gas into the vacuum chamber; and (d) applying microwave energy to the gas to produce a microwave plasma of the gas within the vacuum chamber so that the patterned metal layer is acted by the microwave plasma and formed into a plurality of spaced apart metal nanoparticles on the substrate.
    Type: Application
    Filed: May 22, 2009
    Publication date: August 19, 2010
    Inventors: Kuan-Jiuh Lin, Chuen-Yuan Hsu
  • Patent number: 7714248
    Abstract: The present invention discloses a microwave plasma generator which includes a chamber, a conductive inorganic substance, a trace gas and a microwave source. The conductive inorganic substance and the trace gas are housed in the chamber with an inner pressure about 0.001˜10 torr. By irradiating the conductive inorganic substance and exciting the trace gas, clean and uniform plasma will be generated. The plasma generator of this invention is easily operated and can be applied to semiconductor manufacturing processes, for example, material modification, etching/cleaning, roughing and ion doping/hybrid.
    Type: Grant
    Filed: May 24, 2006
    Date of Patent: May 11, 2010
    Inventors: Kuan-Jiuh Lin, Jun-Wei Su, Chuen-Yuan Hsu
  • Publication number: 20070272663
    Abstract: The present invention discloses a microwave plasma generator which includes a chamber, a conductive inorganic substance, a trace gas and a microwave source. The conductive inorganic substance and the trace gas are housed in the chamber with an inner pressure about 0.001˜10 torr. By irradiating the conductive inorganic substance and exciting the trace gas, clean and uniform plasma will be generated. The plasma generator of this invention is easily operated and can be applied to semiconductor manufacturing processes, for example, material modification, etching/cleaning, roughing and ion doping/hybrid.
    Type: Application
    Filed: May 24, 2006
    Publication date: November 29, 2007
    Inventors: Kuan-Jiuh Lin, Jun-Wei Su, Chuen-Yuan Hsu