Patents by Inventor Chuen-Yuan Hsu
Chuen-Yuan Hsu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20200230595Abstract: An immunodetection method is provided, including: providing a disk; providing a capture antibody on a substrate adding a sample to a reservoir; applying a first rotational speed to transfer the sample containing an antigen from the reservoir to a reaction chamber applying a second rotational speed to precipitate the sample on the substrate so as to combine the antigen in the sample with the capture antibody to obtain a first complex; using capillary force to make the sample flow out of the reaction chamber and to fill the flow channel; applying a third rotational speed to transfer the sample from the flow channel to the waste chamber; providing a detection antibody on the substrate to combine the detection antibody with the first complex to obtain a second complex; and detecting a spectral signal from the localized surface plasma resonance of the second complex.Type: ApplicationFiled: January 9, 2020Publication date: July 23, 2020Inventors: Chih-Hsin Shih, Ho-Chin Wu, Cheng-Liang Lee, Chuen-Yuan Hsu
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Publication number: 20190391137Abstract: A method for manufacturing a measuring kit is disclosed. The method for manufacturing a measuring kit includes steps of providing a carrier including a substrate having a surface; coating a silane onto the surface of the substrate; providing an organic molecule; adding the organic molecule onto the carrier; outputting a microwave energy by a coaxial cable; and emitting the microwave energy through a radiator to microwave the carrier and the organic molecule uniformly to coat the organic molecule onto the carrier carrying the silane, wherein the measuring kit is used to apply an enzyme-linked immunosorbent assay.Type: ApplicationFiled: September 9, 2019Publication date: December 26, 2019Inventors: Chuen-Yuan Hsu, Yi-Heui Hsieh, Chiao-Wen Huang
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Publication number: 20190011444Abstract: A sensing method is disclosed. The sensing method includes steps of providing a carrier including a hole having a bottom, wherein a plurality of spaced apart first nanoparticles are disposed on the bottom; coating a sensing molecule in the hole; providing a testing solution having a testing parameter to the hole, wherein the testing solution has a complex including a testing molecule and a second nanoparticle, and a specific binding occurs between the testing molecule and the sensing molecule; centrifuging the carrier to subside the complex; washing the hole; and measuring a synthetic spectral signal change of the first nanoparticle and the second nanoparticle according to a degree of the specific binding between the testing molecule and the sensing molecule to determine the testing parameter of the testing solution.Type: ApplicationFiled: March 8, 2018Publication date: January 10, 2019Inventors: Chuen-Yuan Hsu, Yi-Heui Hsieh, Chiao-Wen Huang, Ting Liu
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Publication number: 20180267026Abstract: A method for manufacturing a measuring kit is disclosed. The method for manufacturing a measuring kit includes steps of providing a carrier including a substrate having a surface; coating a silane onto the surface of the substrate; providing an organic molecule; adding the organic molecule onto the carrier; outputting a microwave energy by a coaxial cable; and emitting the microwave energy through a radiator to microwave the carrier and the organic molecule uniformly to coat the organic molecule onto the carrier carrying the silane, wherein the measuring kit is used to apply an enzyme-linked immunosorbent assay.Type: ApplicationFiled: March 13, 2018Publication date: September 20, 2018Inventors: Chuen-Yuan Hsu, Yi-Heui Hsieh, Chiao-Wen Huang
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Publication number: 20160327554Abstract: A sensing chip for sensing a first organic molecule in a sample is disclosed. The sensing chip includes a substrate, wherein there are a plurality of separated nanometers on the substrate and a plurality of local substrate surfaces among the plurality of separated nanometers; a silane fixed on the plurality of local substrate surfaces; and a second organic molecule fixed on surfaces of the separated nanometers, wherein there is specificity between the second organic molecule and the first organic molecule.Type: ApplicationFiled: May 6, 2016Publication date: November 10, 2016Inventors: Ying-Cheng Hung, Chuen-Yuan Hsu, Yi-Heui Hsieh, Chiao-Wen Huang
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Patent number: 9091683Abstract: A method of fabricating a biosensor chip includes: forming at least one metallic layer on a transparent substrate to form a composite member; disposing the composite member in a vacuumed chamber, and introducing a gas into the vacuumed chamber; applying microwave energy to the gas to produce a microwave plasma of the gas within the vacuumed chamber, and causing the microwave plasma to interact with the metallic layer so that the metallic layer is melted and formed into a plurality of metallic nanoparticles that are spaced apart from each other and that expose partially the surface of the transparent substrate; and disposing a receptor at the surface of the transparent substrate that is exposed among the metallic nanoparticles. A biosensor chip is also disclosed.Type: GrantFiled: April 1, 2013Date of Patent: July 28, 2015Assignee: NATIONAL CHUNG-HSING UNIVERSITYInventors: Kuan-Jiuh Lin, Chuen-Yuan Hsu
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Publication number: 20150204865Abstract: A sensing method, comprising steps of causing a first molecule to be adjacent to one of a plurality of first nanoparticles spacedly disposed on a detachable chip; adding a target object to contact the first molecule; and measuring a spectral signal, wherein a variation of the spectral signal of the plurality of first nanoparticles occurs when the target object demonstrates a first specific binding with the first molecule.Type: ApplicationFiled: January 21, 2015Publication date: July 23, 2015Applicant: SIWARD CRYSTAL TECHNOLOGY CO., LTD.Inventors: Kuan-Jiuh Lin, Chuen-Yuan Hsu, Wei-Hung Chen, Yi-Heui Hsieh, Yun-Ting Chiang, Jia Yu Chang
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Patent number: 8697196Abstract: A method of forming a metal pattern comprises: (a) providing a substrate; (b) depositing at least one patterned metal layer which includes a metal selected from an inert metal, an inert metal alloy, and combinations thereof; (c) disposing the substrate and the patterned metal layer in a vacuum chamber, vacuuming the vacuum chamber, and introducing a gas into the vacuum chamber; and (d) applying microwave energy to the gas to produce a microwave plasma of the gas within the vacuum chamber so that the patterned metal layer is acted by the microwave plasma and formed into a plurality of spaced apart metal nanoparticles on the substrate.Type: GrantFiled: May 22, 2009Date of Patent: April 15, 2014Inventors: Kuan-Jiuh Lin, Chuen-Yuan Hsu
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Patent number: 8663554Abstract: A method of fabricating a biosensor chip includes: forming at least one metallic layer on a transparent substrate to form a composite member; disposing the composite member in a vacuumed chamber, and introducing a gas into the vacuumed chamber; applying microwave energy to the gas to produce a microwave plasma of the gas within the vacuumed chamber, and causing the microwave plasma to interact with the metallic layer so that the metallic layer is melted and formed into a plurality of metallic nanoparticles that are spaced apart from each other and that expose partially the surface of the transparent substrate; and disposing a receptor at the surface of the transparent substrate that is exposed among the metallic nanoparticles. A biosensor chip is also disclosed.Type: GrantFiled: August 18, 2010Date of Patent: March 4, 2014Inventors: Kuan-Jiuh Lin, Chuen-Yuan Hsu
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Publication number: 20130230427Abstract: A method of fabricating a biosensor chip includes: forming at least one metallic layer on a transparent substrate to form a composite member; disposing the composite member in a vacuumed chamber, and introducing a gas into the vacuumed chamber; applying microwave energy to the gas to produce a microwave plasma of the gas within the vacuumed chamber, and causing the microwave plasma to interact with the metallic layer so that the metallic layer is melted and formed into a plurality of metallic nanoparticles that are spaced apart from each other and that expose partially the surface of the transparent substrate; and disposing a receptor at the surface of the transparent substrate that is exposed among the metallic nanoparticles. A biosensor chip is also disclosed.Type: ApplicationFiled: April 1, 2013Publication date: September 5, 2013Inventors: Kuan-Jiuh Lin, Chuen-Yuan Hsu
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Publication number: 20120015164Abstract: A glass product includes a glass substrate, and a metallic nano-network layer embedded and continuously extending in the glass substrate. A method for producing the glass product is also disclosed.Type: ApplicationFiled: July 14, 2011Publication date: January 19, 2012Inventors: Kuan-Jiuh Lin, Chuen-Yuan Hsu
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Publication number: 20110044857Abstract: A method of fabricating a biosensor chip includes: forming at least one metallic layer on a transparent substrate to form a composite member; disposing the composite member in a vacuumed chamber, and introducing a gas into the vacuumed chamber; applying microwave energy to the gas to produce a microwave plasma of the gas within the vacuumed chamber, and causing the microwave plasma to interact with the metallic layer so that the metallic layer is melted and formed into a plurality of metallic nanoparticles that are spaced apart from each other and that expose partially the surface of the transparent substrate; and disposing a receptor at the surface of the transparent substrate that is exposed among the metallic nanoparticles. A biosensor chip is also disclosed.Type: ApplicationFiled: August 18, 2010Publication date: February 24, 2011Inventors: Kuan-Jiuh Lin, Chuen-Yuan Hsu
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Publication number: 20100206720Abstract: A method of producing inorganic nanoparticles includes: (a) providing a layered structure including a substrate and an inorganic layer; (b) disposing the layered structure in a vacuum chamber, vacuuming the vacuum chamber, and introducing a gas into the vacuum chamber; and (c) applying microwave energy to the gas to produce a microwave plasma of the gas within the vacuum chamber so that the inorganic layer is acted by the microwave plasma and formed into a plurality of inorganic nanoparticles on the substrate. A system for producing the nanoparticles is also disclosed.Type: ApplicationFiled: May 22, 2009Publication date: August 19, 2010Inventors: Kuan-Jiuh Lin, Chuen-Yuan Hsu
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Publication number: 20100209617Abstract: A method of forming a metal pattern comprises: (a) providing a substrate; (b) depositing at least one patterned metal layer which includes a metal selected from an inert metal, an inert metal alloy, and combinations thereof; (c) disposing the substrate and the patterned metal layer in a vacuum chamber, vacuuming the vacuum chamber, and introducing a gas into the vacuum chamber; and (d) applying microwave energy to the gas to produce a microwave plasma of the gas within the vacuum chamber so that the patterned metal layer is acted by the microwave plasma and formed into a plurality of spaced apart metal nanoparticles on the substrate.Type: ApplicationFiled: May 22, 2009Publication date: August 19, 2010Inventors: Kuan-Jiuh Lin, Chuen-Yuan Hsu
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Patent number: 7714248Abstract: The present invention discloses a microwave plasma generator which includes a chamber, a conductive inorganic substance, a trace gas and a microwave source. The conductive inorganic substance and the trace gas are housed in the chamber with an inner pressure about 0.001˜10 torr. By irradiating the conductive inorganic substance and exciting the trace gas, clean and uniform plasma will be generated. The plasma generator of this invention is easily operated and can be applied to semiconductor manufacturing processes, for example, material modification, etching/cleaning, roughing and ion doping/hybrid.Type: GrantFiled: May 24, 2006Date of Patent: May 11, 2010Inventors: Kuan-Jiuh Lin, Jun-Wei Su, Chuen-Yuan Hsu
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Publication number: 20070272663Abstract: The present invention discloses a microwave plasma generator which includes a chamber, a conductive inorganic substance, a trace gas and a microwave source. The conductive inorganic substance and the trace gas are housed in the chamber with an inner pressure about 0.001˜10 torr. By irradiating the conductive inorganic substance and exciting the trace gas, clean and uniform plasma will be generated. The plasma generator of this invention is easily operated and can be applied to semiconductor manufacturing processes, for example, material modification, etching/cleaning, roughing and ion doping/hybrid.Type: ApplicationFiled: May 24, 2006Publication date: November 29, 2007Inventors: Kuan-Jiuh Lin, Jun-Wei Su, Chuen-Yuan Hsu