Patents by Inventor Chul-Soo Cho

Chul-Soo Cho has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 8-oxoprotoberberine derivative or pharmaceutically acceptable salt thereof, preparation method therefor and pharmaceutical composition for preventing or treating diseases associated with activity of NFAT5, containing same as active ingredient
    Patent number: 9650389
    Abstract: The preset invention relates to a novel 8-oxoprotoberberine derivative or a pharmaceutically acceptable salt thereof, a preparation method thereof, and a pharmaceutical composition for preventing or treating diseases associated with the activity of NFAT5 containing the same as an active ingredient. The novel 8-oxoproteoberberine derivative or the pharmaceutically acceptable salt thereof according to the present invention can be useful in a pharmaceutical composition for preventing or treating diseases associated with the activity of NFAT5, particularly rheumatoid arthritis or inflammatory diseases, since it is ascertained that the derivative or a pharmaceutically acceptable salt thereof has remarkably increased oral absorption compared with known protoberberine due to an improvement in the properties thereof, and inhibits the activity of NFAT5 and the secretion of inflammatory cytokines and reduces the expression of NAFT5 in mice with rheumatoid arthritis by directly inhibiting the transcription of NFT5.
    Type: Grant
    Filed: December 30, 2014
    Date of Patent: May 16, 2017
    Assignees: Korea Research Institute of Chemical Technology, The Catholic University of Korea Industry-Academic Cooperation Foundation
    Inventors: Heeyeong Cho, Hee-Jong Lim, Ge Hyeong Lee, Woo Kyu Park, Hyeon Young Kim, Dae Young Jeong, Wan Uk Kim, Chul Soo Cho, Su Jung Park, Eun Jin Han
  • Novel 8-Oxoprotoberberine Derivative or Pharmaceutically Acceptable Salt Thereof, Preparation Method Therefor and Pharmaceutical Composition for Preventing or Treating Diseases Associated with Activity of NFAT5, Containing Same as Active Ingredient
    Publication number: 20160251368
    Abstract: The preset invention relates to a novel 8-oxoprotoberberine derivative or a pharmaceutically acceptable salt thereof, a preparation method thereof, and a pharmaceutical composition for preventing or treating diseases associated with the activity of NFAT5 containing the same as an active ingredient. The novel 8-oxoproteoberberine derivative or the pharmaceutically acceptable salt thereof according to the present invention can be useful in a pharmaceutical composition for preventing or treating diseases associated with the activity of NFAT5, particularly rheumatoid arthritis or inflammatory diseases, since it is ascertained that the derivative or a pharmaceutically acceptable salt thereof has remarkably increased oral absorption compared with known protoberberine due to an improvement in the properties thereof, and inhibits the activity of NFAT5 and the secretion of inflammatory cytokines and reduces the expression of NAFT5 in mice with rheumatoid arthritis by directly inhibiting the transcription of NFT5.
    Type: Application
    Filed: December 30, 2014
    Publication date: September 1, 2016
    Inventors: Heeyeong CHO, Hee-Jong LIM, Ge Hyeong LEE, Woo Kyu PARK, Hyeon Young KIM, Dae Young JEONG, Wan Uk KIM, Chul Soo CHO, Su Jung PARK, Eun Jin HAN
  • Door-closing device using a cam
    Publication number: 20050044661
    Abstract: The present invention relates to a door-closing device with using a cam. In particular, the present invention relates to the door-closing device restoring a door automatically to an original position with using the restoring force of a spring which is generated by the cam, wherein the cam converts rotational movement to rectilinear movement after the door is pushed and opened.
    Type: Application
    Filed: July 30, 2004
    Publication date: March 3, 2005
    Inventor: Chul-Soo Cho