Patents by Inventor Chul Woo LIM

Chul Woo LIM has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PHARMACEUTICAL COMPOSITION COMPRISING NOVEL SD911 COMPOUND AS ACTIVE INGREDIENT FOR PREVENTION OR TREATMENT OF TRANSPLANT REJECTION
    Publication number: 20240131027
    Abstract: The present invention relates to a pharmaceutical composition comprising a novel compound as an active ingredient for prevention or treatment of transplant rejection. The novel compound SD911 of the present invention was identified to repress the migration of immune cells, increase the engraftment and viability of a grafted tissue, and regulate immune cells. In addition, it was found in a kidney transplantation model that the compound restrained human PBMC from suppressing the engraftment and damaging renal tissues and downregulated the expression of the inflammatory cytokine IL-17, with the consequent effective prevention and treatment of transplant rejection.
    Type: Application
    Filed: April 6, 2022
    Publication date: April 25, 2024
    Applicant: THE CATHOLIC UNIVERSITY OF KOREA INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: Chul Woo YANG, Dongyun SHIN, Sun Woo LIM, Mi La CHO, Yoo Jin SHIN, Seon Yeong LEE, A Ram LEE
  • COMPOSITION FOR PROMOTING DIFFERENTIATION OF NEURAL STEM CELLS INTO DOPAMINERGIC NEURONS
    Publication number: 20230330151
    Abstract: Provided are a composition and a method for promoting differentiation of neural stem cells into dopaminergic neurons, the composition including fusaric acid, ascorbic acid, nicotinamide adenine dinucleotide, or a combination thereof. The composition and method according to an aspect may not only increase differentiation of neural stem cells isolated at an early stage of development into dopaminergic neurons, but also increase differentiation of subcultured neural stem cells into dopaminergic neurons, and thus, it is possible to secure more dopaminergic neurons, and increase therapeutic effects on Parkinson's disease.
    Type: Application
    Filed: August 24, 2021
    Publication date: October 19, 2023
    Applicants: CHA UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION, SUNGKWANG MEDICAL FOUNDATION
    Inventors: Jisook MOON, Chul KIM, Jae Hyun PARK, Ji-Min PARK, Young Sook SONG, Chul Woo LIM, Yuri CHOI
  • Biomarker for senescence and anti-senescence and use thereof
    Patent number: 11435368
    Abstract: Provided are a biomarker for diagnosing of the level of senescence, a composition and kit for diagnosing of the level of senescence to detect the biomarker, and a method of diagnosing the same. According to the composition and kit for the diagnosis of the level of senescence and the method of diagnosing senescence, the level of senescence of a subject is easily diagnosed, the health conditions of the subject are monitored, and a senescence-associated disease is prevented or diagnosed.
    Type: Grant
    Filed: November 30, 2018
    Date of Patent: September 6, 2022
    Assignees: CHA University Industry-Academic Cooperation Foundation, The General Hospital Corporation
    Inventors: Ji Sook Moon, Hak Ho Lee, Ala Jo, Jae Hyun Park, Ji Min Park, Chul Woo Lim, Yu Ri Choi
  • BIOMARKER FOR SENESCENCE AND ANTI-SENESCENCE AND USE THEREOF
    Publication number: 20200103422
    Abstract: Provided are a biomarker for diagnosing of the level of senescence, a composition and kit for diagnosing of the level of senescence to detect the biomarker, and a method of diagnosing the same. According to the composition and kit for the diagnosis of the level of senescence and the method of diagnosing senescence, the level of senescence of a subject is easily diagnosed, the health conditions of the subject are monitored, and a senescence-associated disease is prevented or diagnosed.
    Type: Application
    Filed: November 30, 2018
    Publication date: April 2, 2020
    Applicants: CHA University Industry-Academic Cooperation Foundation, The General Hospital Corporation
    Inventors: Ji Sook MOON, Hak Ho LEE, Ala JO, Jae Hyun PARK, Ji Min PARK, Chul Woo LIM, Yu Ri CHOI