Abstract: A power pack for use with a medicament delivery device is presented having a plunger rod movable along a longitudinal axis; a drive spring operably connected to said plunger rod; a plunger rod sleeve arranged with holding elements for releasably holding said plunger rod with said drive spring in a tensioned state. Signal initiating elements are arranged to said plunger rod; and signal generating elements arranged to cooperate with said signal initiating elements for providing information to a user of a medicament delivery device about the movement of said plunger rod when said plunger rod sleeve has been activated to release said holding elements.

Abstract: A power pack for use with a medicament delivery device is presented having a plunger rod movable along a longitudinal axis; a drive spring operably connected to said plunger rod; a plunger rod sleeve arranged with holding elements for releasably holding said plunger rod with said drive spring in a tensioned state. Signal initiating elements are arranged to said plunger rod; and signal generating elements arranged to cooperate with said signal initiating elements for providing information to a user of a medicament delivery device about the movement of said plunger rod when said plunger rod sleeve has been activated to release said holding elements.

Abstract: A power pack for use with a medicament delivery device is presented having a plunger rod movable along a longitudinal axis; a drive spring operably connected to said plunger rod; a plunger rod sleeve arranged with holding elements for releasably holding said plunger rod with said drive spring in a tensioned state. Signal initiating elements are arranged to said plunger rod; and signal generating elements arranged to cooperate with said signal initiating elements for providing information to a user of a medicament delivery device about the movement of said plunger rod when said plunger rod sleeve has been activated to release said holding elements.

Abstract: The present disclosure provides binding agents, such as antibodies, that specifically bind Angiopoietin-like protein 8 (ANGPTL8), including human ANGPTL8, and methods of their use.

Abstract: A power pack for use with a medicament delivery device is presented having a plunger rod movable along a longitudinal axis; a drive spring operably connected to said plunger rod; a plunger rod sleeve arranged with holding elements for releasably holding said plunger rod with said drive spring in a tensioned state. Signal initiating elements are arranged to said plunger rod; and signal generating elements arranged to cooperate with said signal initiating elements for providing information to a user of a medicament delivery device about the movement of said plunger rod when said plunger rod sleeve has been activated to release said holding elements.

Abstract: The present disclosure provides binding agents, such as antibodies, that specifically bind HTRA1, including human HTRA1, as well as compositions comprising the binding agents, and methods of their use. The disclosure also provides related polynucleotides and vectors encoding the binding agents and cells comprising and expressing the binding agents.

Abstract: A power pack for use with a medicament delivery device is presented having a plunger rod movable along a longitudinal axis; a drive spring operably connected to said plunger rod; a plunger rod sleeve arranged with holding elements for releasably holding said plunger rod with said drive spring in a tensioned state. Signal initiating elements are arranged to said plunger rod; and signal generating elements arranged to cooperate with said signal initiating elements for providing information to a user of a medicament delivery device about the movement of said plunger rod when said plunger rod sleeve has been activated to release said holding elements.

Abstract: A supplementary device configured to be mounted externally to a medicament delivery device provided with a dose setting knob, wherein the supplementary device has a sleeve configured to be arranged around a portion of the medicament delivery device, wherein the sleeve has a main body having a proximal sleeve end and a distal sleeve end, wherein the main body is provided with a flexible dose setting knob positioning structure which extend distally from the distal sleeve end.

Abstract: A sub-assembly for a medicament delivery device is presented having a cap provided with a distal opening and configured to be mounted to a proximal end of the medicament delivery device. A tubular remover is received in the distal opening of the cap, the remover having a proximal end portion fixedly attached to the cap, a housing with an internal structure and provided with a proximal inclined surface. The remover has a plurality of radially flexible legs extending longitudinally from a proximal end of the remover to a distal end thereof, each leg having a gripper that engages with a delivery member shield of the medicament delivery device and having a guide finger configured to extend distally beyond the grippers or cooperating with an internal structure of the medicament delivery device to guide radial expansion of the legs when the remover is mounted in the medicament delivery device.

Abstract: A power pack for use with a medicament delivery device is presented having a plunger rod movable along a longitudinal axis; a drive spring operably connected to said plunger rod; a plunger rod sleeve arranged with holding elements for releasably holding said plunger rod with said drive spring in a tensioned state. Signal initiating elements are arranged to said plunger rod; and signal generating elements arranged to cooperate with said signal initiating elements for providing information to a user of a medicament delivery device about the movement of said plunger rod when said plunger rod sleeve has been activated to release said holding elements.

Abstract: A plunger unit is presented having rod member and a plunger body, movably mounted to the rod member, a striker movably mounted between the plunger body and the rod member, and a first biasing member urging the plunger body and the rod member, wherein the striker impacts the plunger body to create signals when the first biasing member activates a movement of the plunger body relative to the rod member. A medicament delivery device is also presented having a proximal sub-assembly and a distal sub-assembly movably connected to the proximal sub-assembly, where the plunger unit is received in the distal sub-assembly.

Abstract: A plunger unit is presented having rod member and a plunger body, movably mounted to the rod member, a striker movably mounted between the plunger body and the rod member, and a first biasing member urging the plunger body and the rod member, wherein the striker impacts the plunger body to create signals when the first biasing member activates a movement of the plunger body relative to the rod member. A medicament delivery device is also presented having a proximal sub-assembly and a distal sub-assembly movably connected to the proximal sub-assembly, where the plunger unit is received in the distal sub-assembly.

Abstract: The present disclosure provides binding agents, such as antibodies, that specifically bind Angiopoietin-like protein 8 (ANGPTL8), including human ANGPTL8, and methods of their use.

Abstract: The present disclosure provides binding agents, such as antibodies, that specifically bind Angiopoietin-like protein 8 (ANGPTL8), including human ANGPTL8, and methods of their use.

Abstract: A medicament delivery device includes a holding unit (5), a driving unit (7) releasably held by the holding unit, an activation unit (6) used to release the driving unit from the holding unit, and an injection unit (8) to be moved by the driving unit. The injection unit includes a hub (85) held by the driving unit, a cannula (86) fixed to the hub and a container (83) slidably connected to the hub. After the driving unit is released, the proximal end of the cannula protrudes out of the activation unit before the distal end of the cannula fluidly communicates with the container. The medicament delivery device is combined with an electronic device in an assembly. When a casing cap of the assembly is removed, the electronic device or an app in the electronic device or a function of the electronic device is automatically activated to wirelessly communicate with another electronic device.

Abstract: The present disclosure relates to a sub-assembly for a medicament delivery device, comprising: a cap having a tubular body provided with a distal opening, the cap being configured to be mounted to a proximal end of a medicament delivery device, and a tubular remover configured to be received in the distal opening of the cap, the remover having a proximal end portion configured to be fixedly attached to the cap, a housing, an internal structure arranged inside the housing and provided with a proximal inclined surface, and wherein the remover has a plurality of radially flexible legs extending longitudinally from a proximal end of the remover to a distal end thereof, each leg having a gripper configured to engage with a delivery member shield of a medicament delivery device, and each leg having a guide finger configured to extend distally beyond the grippers for cooperating with an internal structure of a medicament delivery device to guide radial expansion of the legs when the remover is mounted in a medicamen

Abstract: The present disclosure provides binding agents, such as antibodies, that specifically bind Angiopoietin-like protein 8 (ANGPTL8), including human ANGPTL8, and methods of their use.

Abstract: A medicament delivery device includes a holding unit (5), a driving unit (7) releasably held by the holding unit, an activation unit (6) used to release the driving unit from the holding unit, and an injection unit (8) to be moved by the driving unit. The injection unit includes a hub (85) held by the driving unit, a cannula (86) fixed to the hub and a container (83) slidably connected to the hub. After the driving unit is released, the proximal end of the cannula protrudes out of the activation unit before the distal end of the cannula fluidly communicates with the container. The medicament delivery device is combined with an electronic device in an assembly. When a casing cap of the assembly is removed, the electronic device or an app in the electronic device or a function of the electronic device is automatically activated to wirelessly communicate with another electronic device.

Abstract: Sending apparatus, receiving apparatus, sending method, receiving method and sending and receiving system for supporting application based MMS. The body of an incremental MMS includes a dynamic data section of MMS, a static data indicator associated with the MMS, and a link tag between indicated static data and the dynamic data. The amount of the message quantity transmitted may be reduced because the changed section of the incremental MMS is sent directly via short message channel in dynamic data mode. In turn, the incremental MMS may be sent via short message channel instead of MMS channel due to the reduction of transmitted message, which further reduces the communication cost.

Abstract: An all-in-one adapter container. The all-in-one adapter container comprises a space, a cover covering the space, at least one power line, a printed circuit board (PCB) and at least one line-arranging mechanism. The line-arranging mechanism provides arrangement for the power line. The printed circuit board is electrically connected to the power line.