Patents by Inventor Chun-Fung Chan

Chun-Fung Chan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Molecules and methods for demethylation of methylated nucleic acid sequences
    Patent number: 8658393
    Abstract: Demethylation of a methylated DNA sequence in a eukaryotic cell is described, utilizing a molecule that includes at least a first domain that exhibits a cytidine deaminase activity and at least a second domain that confers either a specific or non-specific DNA binding activity. The molecules of the invention are useful in somatic cell nuclear transfer and also in cancer therapy.
    Type: Grant
    Filed: October 5, 2012
    Date of Patent: February 25, 2014
    Assignee: CellCentric Limited
    Inventors: Wolf Reik, Hugh Morgan, Chun-Fung Chan
  • Compositions and method for epigenetic modification of nucleic acid sequences in vivo
    Patent number: 8298529
    Abstract: Demethylation of a methylated DNA sequence in a eukaryotic cell is described, utilizing a molecule that includes at least a first domain that exhibits a cytidine deaminase activity and at least a second domain that confers either a specific or non-specific DNA binding activity. The molecules of the invention are useful in somatic cell nuclear transfer and also in cancer therapy.
    Type: Grant
    Filed: April 10, 2007
    Date of Patent: October 30, 2012
    Assignee: CellCentric Limited
    Inventors: Wolf Reik, Hugh Morgan, Chun-Fung Chan
  • Compositions and Method for Epigenetic Modification of Nucleic Acid Sequences in Vivo
    Publication number: 20110138491
    Abstract: Demethylation of a methylated DNA sequence in a eukaryotic cell is described, utilising a molecule that includes at least a first domain that exhibits a cytidine deaminase activity and at least a second domain that confers either a specific or non-specific DNA binding activity. The molecules of the invention are useful in somatic cell nuclear transfer and also in cancer therapy.
    Type: Application
    Filed: April 10, 2007
    Publication date: June 9, 2011
    Applicant: CellCentric Limited
    Inventors: Wolf Reik, Hugh Morgan, Chun-Fung Chan