Abstract: Provided is the use of isocitrate dehydrogenase (IDH1 and IDH2) mutations for selecting and treating cancer patients for zotiraciclib (TG02) therapy, for example, in treating cancers such as glioma, medulloblastoma, chondrosarcoma, cholangiocarcinoma, AML, astrocytoma, and others, as a single agent of in conjunction with other chemotherapeutics

Abstract: The present disclosure relates to the technical field of electric curtains and in particular to an electric curtain system and a travel setting method thereof. The system comprises a motor and a controller. The controller is electrically connected with the motor. The electric curtain system further comprises at least two travel setting keys, which are an up travel setting key and a down travel setting key respectively. The up travel setting key and the down travel setting key are both electrically connected with the controller. This travel setting method helps the users perform travel setting in a convenient way.

Abstract: A rotatable and adjustable dumbbell, with radial grooves and radial protrusions arranged on left and right sides of dumbbell plates respectively, more than two groove-end axial baffle plates evenly arranged on the radial grooves, inner connecting grooves arranged inside the groove-end axial baffle plates, more than two protrusion-end axial baffle plates evenly provided on outer end surfaces of the radial protrusions, and outer connecting grooves provided in the protrusion-end axial baffle plates. The dumbbell plates and an inner end plate are both provided with guide grooves at outer diameters, a lower portion of lock button switches is provided with at least one connecting gap and at least one connecting protrusion, at least one guide plate and at least one inner guide groove are provided inside the dumbbell plates, the guide plate is inserted into the connecting gap, and the connecting protrusion is inserted into the inner guide groove.

Abstract: It relates to 1-(2-methoxyethyl)-2-methyl-4, 9-dioxo-3-(pyrazin-2-ylmethyl)-4, 9-dihydro-1H-naphtho [2, 3-d]imidazolium pamoate or solvate thereof, pharmaceutical composition comprising the pamoate salt or solvate, and therapeutic uses thereof. In particular, the pamoate salt or solvate is useful for treating cancer which has a c-My rearrangement and/or MYCN amplification or overexpression.

Abstract: A transgenic soybean event XP-2 and a detection method thereof. The transgenic soybean event XP-2 utilizes the nucleotide sequence shown in SEQ ID NO:27 as the left flanking region of the exogenous genes and the nucleotide sequence shown in SEQ ID NO:28 as the right flanking region of the exogenous genes. The transgenic soybean event XP-2 co-localizes genes encoding glyphosate tolerance and flazasulfuron tolerance traits on the same DNA segment, and these genes are integrated into a single locus within the genome of the transgenic soybean event XP-2. This configuration provides enhanced breeding efficiency and enables the use of molecular markers to track the transgenic insert in breeding populations and their progeny. The specific nucleic acid sequences for detecting soybean plants allow for the unique identification of transgenic soybean event XP-2.

Abstract: A rotary positioning dumbbell combination structure and a dumbbell adopting the combination structure, and the rotary positioning dumbbell combination structure comprises at least one dumbbell plate body, and at least one of at least one radial protrusion or at least one radial groove is arranged on left and right sides of the at least one dumbbell plate body; at least one radial groove and at least one radial protrusion are matched; the at least one positioning protrusion is provided in the at least one radial groove; at least one radial elastic sheet is provided on the at least one radial protrusion; and the at least one positioning groove is provided on the at least one radial elastic sheet at a position facing the at least one positioning protrusion.

Abstract: A double-row rope winder for a curtain and an electric curtain are provided which comprise a rope winder seat; at least two winding core mounting grooves are juxtaposed on the rope winder seat; a winding core is disposed in the winding core mounting grooves respectively; a first rotary part and a second rotary part are respectively disposed at both ends of the winding cores; a first supporting part and a second supporting part cooperating with the first rotary part and the second rotary part respectively are disposed respectively at both ends of the winding core mounting grooves; a first rope guide hole and a second rope guide hole are symmetrically disposed at both ends inside the winding core mounting grooves; a third rope guide hole and a fourth rope guide hole are symmetrically disposed at both ends between the two adjacent winding core mounting grooves on the rope winder seat.

Abstract: The present invention discloses a double-layer day-night curtain system and a control method thereof; the system comprises an upper rail, a transmission mechanism inside the upper rail, two curtain assemblies connected to the transmission mechanism, a drive mechanism connected to the upper rail to drive the transmission mechanism, and the two curtain assemblies are disposed in parallel; the control method thereof comprises step A1, select the controller according to the curtain assembly: remote controller X for left-right type curtain assembly, and match it with the controller, and proceed to the next step; select remote controller Y for up-down type curtain assembly, and match it with the controller, and skip to step A3; step A2, the controller automatically switches to the control method for controlling the left-right type curtain assembly when matched; step A3, the controller automatically switches to the control method for controlling the up-down type curtain assembly when matched.

Abstract: An electric curtain is provided which comprises a top rail, a bottom bar, a curtain body, a rope winding assembly, a drive device and an end seal; the top rail and the bottom bar are disposed in parallel up and down with the curtain body in between; the top rail is provided with opposed first end and second end; the end seal is disposed at the first end of the top rail and the drive device at the second end; the drive device is in transmission connection with the rope winding assembly; the drive device comprises a motor part and a power supply part; the motor part is disposed inside the top rail and connected to the rope winding assembly in a transmission manner; the power supply part is disposed outside the top rail; the motor part and the power supply part are disposed in parallel inside and out.

Abstract: An integrated drive device is provided which comprises a motor component and a power source component; the motor component is provided with an opposed first end and second end; the first end of the motor component is a power output end; the power source component is detachably and electrically connected with the second end of the motor component; the power source component and the motor component are disposed back and forth in parallel. The integrated drive device as a finished product has a more integrated structure and can be quickly mounted onto and dismounted from a top track of a curtain, saving time and labor in assembling process. The drive device can be adapted to a single-chamber top track of a curtain as well as short and long curtains, and the power source component is detachable, which helps transportation and storage, avoiding occurrence of potential safety hazards.

Abstract: The present disclosure provides a quickly-mounted ceiling curtain, which comprises a frame body formed by connecting a top beam, a bottom beam and two side beams. At least one end of the top beam is provided with a holing-free mounting member for supporting the frame body on a mounting position of a building. At least one end of the bottom beam is provided with a holing-free mounting member for supporting the frame body on the mounting position of the building. With the holing-free mounting members provided on the top beam and the bottom beam of the frame body, the ceiling curtain is supported on the mounting position of the building, realizing quick and holing-free mounting of the ceiling curtain without drilling holes with auxiliary tools, and thus saving time and labor and improving mounting efficiency.