Patents by Inventor Chun-Jun Guo

Chun-Jun Guo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS AND COMPOSITIONS FOR GENETICALLY MODIFYING HUMAN GUT MICROBES
    Publication number: 20250034579
    Abstract: Dysbiosis has been linked to diseases such as inflammatory bowel disease and obesity. Multi-omics studies have uncovered significant associations between microbiota genes and diseases. Many of these genes are exclusively expressed in non-model microbes such as Firmicutes/Clostridia. A pipeline for building microbial genetic manipulation systems would be a first step to manipulating these genes in vivo and causally connecting them with host diseases. The present technology relates generally to compositions and the methods of preparations thereof for genetically engineering gut-microbiota in vitro. The present technology further relates to uses of compositions in vivo.
    Type: Application
    Filed: December 6, 2022
    Publication date: January 30, 2025
    Applicant: Cornell University
    Inventors: Chun-Jun GUO, Wenbing JIN, Tingting LI
  • Compositions and methods for modulating protease activity
    Patent number: 11124498
    Abstract: Disclosed herein, inter alia, are compositions for modulating protease activity and treating cancer.
    Type: Grant
    Filed: November 15, 2017
    Date of Patent: September 21, 2021
    Assignees: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, MASSACHUSETTS INSTITUTE OF TECHNOLOGY, PRESIDENT AND FELLOWS OF HARVARD COLLEGE
    Inventors: Michael A. Fischbach, Chun-Jun Guo, Christopher A. Voigt, Fang-Yuan Chang, Jon Clardy, Thomas Wyche
  • COMPOSITIONS AND METHODS FOR MODULATING PROTEASE ACTIVITY
    Publication number: 20200048227
    Abstract: Disclosed herein, inter alia, are compositions for modulating protease activity and treating cancer.
    Type: Application
    Filed: November 15, 2017
    Publication date: February 13, 2020
    Inventors: Michael A. Fischbach, Chun-Jun Guo, Christopher A. Voigt, Fang-Yuan Chang, Jon Clardy, Thomas Wyche