Abstract: Apparatus for manually controlling a motorized microscope stage for movement about the X, Y and Z axes. The apparatus includes a main housing having an X axis control knob and a Y axis control knob rotatably mounted to the housing. A Z axis control knob is provided for controlling movement about the Z axis. The Z axis knob is mounted to a removable module so that the position of the Z axis control knob is adjustable with respect to the other knobs. There is a controller for generating stage control signals in response to movement of the knobs. A plug-in connector connects the apparatus to the microscope stage controller such that the stage control signals create corresponding movements of the motorized stage. The apparatus simulates the controls of a nonmotorized stage while maintaining compatibility with existing stage controller units. The apparatus is designed to provide tactile position feedback to the user similar to that of a manual non-motorized microscope.