Abstract: A method for alleviating dry eye disease includes administering to a subject in need thereof a pharmaceutical composition containing an ethanol-extracted product of fruiting bodies of Cordyceps militaris, and the dry eye disease may be caused by a factor selected from the group consisting of a sleep disorder, aging, Sjögren's syndrome, a particulate matter (PM), and combinations thereof.

Abstract: The present invention relates to an antagonist of interleukin-17B receptor (IL-17RB) which features interruption of the interaction of IL-17RB and MLK4. The present invention also relates to use of such antagonist for treatment of diseases or disorders associated with IL-17RB activation. Further disclosed is a phosphorylated IL-17RB as a biomarker for predicting prognosis and/or monitoring progression of cancer.

Abstract: A method for delivering sports telemetry for a curling game provides players, coaches, and viewers with the detailed dynamics of a curling stone. The method is generalized to at least one computerized sports equipment in communication with at least one remote server. A sensing module of the sports equipment captures and sends an angular-motion measurement and a linear-motion measurement to the remote server. Further, a tracking module of the sports equipment sends a precise location reading to the remote server. The angular-motion measurement, the linear-motion measurement, and the precise location reading are compiled into a sports telemetry data. Subsequently, the sports telemetry data assess a plurality of summarization metrics which promotes game awareness and interest. Further, the sports telemetry data also generates at least one equipment motion animation of play-by-play breakdown of the game. Finally, an online view platform allows the general public to access the sports telemetry data.

Abstract: A method for delivering sports telemetry for a curling game provides players, coaches, and viewers with the detailed dynamics of a curling stone. The method is generalized to at least one computerized sports equipment in communication with at least one remote server. A sensing module of the sports equipment captures and sends an angular-motion measurement and a linear-motion measurement to the remote server. Further, a tracking module of the sports equipment sends a precise location reading to the remote server. The angular-motion measurement, the linear-motion measurement, and the precise location reading are compiled into a sports telemetry data. Subsequently, the sports telemetry data assess a plurality of summarization metrics which promotes game awareness and interest. Further, the sports telemetry data also generates at least one equipment motion animation of play-by-play breakdown of the game. Finally, an online view platform allows the general public to access the sports telemetry data.

Abstract: A camera module includes a circuit board, a camera device and an image processing chip. An image sensation chip of the camera device is directly integrated with the circuit board by means of chip-on-board (COB) manufacturing process to minify the total volume of the camera module, whereby the camera module can be disposed in a narrow space.

Abstract: PFC device and controlling method thereof, and an electronic device are provided. The device includes: first and second input terminals configured to receive AC input signal including alternating positive and negative half-cycles; an output terminal configured to provide output signal; an inductor a first terminal of which is coupled with the first input terminal; a first bridge arm including first and second switch components whose first connection point is coupled with second terminal of the inductor; a second bridge arm including third and fourth switch components whose second connection point is coupled with the second input terminal; a first current sampling unit configured to sample falling edge of an inductor current flowing through the inductor; a switch controlling unit configured to generate switch control signal based on sampling result to control the first and second switch components to change switch status. Influence of parasitic parameters on the circuit is reduce.

Abstract: A camera module includes a circuit board, a camera device and an image processing chip. An image sensation chip of the camera device is directly integrated with the circuit board by means of chip-on-board (COB) manufacturing process to minify the total volume of the camera module, whereby the camera module can be disposed in a narrow space.

Abstract: PFC device and controlling method thereof, and an electronic device are provided. The device includes: first and second input terminals configured to receive AC input signal including alternating positive and negative half-cycles; an output terminal configured to provide output signal; an inductor a first terminal of which is coupled with the first input terminal; a first bridge arm including first and second switch components whose first connection point is coupled with second terminal of the inductor; a second bridge arm including third and fourth switch components whose second connection point is coupled with the second input terminal; a first current sampling unit configured to sample falling edge of an inductor current flowing through the inductor; a switch controlling unit configured to generate switch control signal based on sampling result to control the first and second switch components to change switch status.

Abstract: The invention provides for methods for treating gastric cancer or colon cancer in a subject by administering a cholinergic antagonist, a Botulinum toxin, a NGF inhibitior, a TRK inhibitor, or performing a surgical denervation. The invention provides for inhibiting stem cells growth by administering a cholinergic antagonist, a Botulinum toxin, a NGF inhibitior, a TRK inhibitor, or performing a surgical denervation. The invention provides for stimulating regeneration of the colon or stomach by administering a cholinergic agonist.

Abstract: Certain embodiments of the present invention provide selected compounds having a molecular structure according to Formula 1: In Formula 1, Z is —CO—, —SO—, or —SO2—; Ar is phenyl, heteroaryl, or heterocycloalkyl; Het is heteroaryl; R is R?, X, or NR1R2; R? is R3, or OR3; R? is R4, or OR4; R1 and R2 are each independently H, alkyl, or acyl; R3 is H, heteroaryl, or alkyl; R4 is H, heteroaryl, or CnH2n+1 (n>2); and X is F, Br, I, CN, or NO2. In some embodiments, compounds having a molecular structure according to Formula 1 have the property of inhibiting a growth of a cell line selected from HeLa and MB468 with a sub-micromolar IC50.

Abstract: Certain embodiments of the present invention provide selected compounds having a molecular structure according to Formula 1: In Formula 1, Z is —CO—, —SO—, or —SO2—; Ar is phenyl, heteroaryl, or heterocycloalkyl; Het is heteroaryl; R is R?, X, or NR1R2; R? is R3, or OR3; R? is R4, or OR4; R1 and R2 are each independently H, alkyl, or acyl; R3 is H, heteroaryl, or alkyl; R4 is H, heteroaryl, or CnH2n+1 (n>2); and X is F, Br, I, CN, or NO2. In some embodiments, compounds having a molecular structure according to Formula 1 have the property of inhibiting a growth of a cell line selected from HeLa and MB468 with a sub-micromolar IC50.

Abstract: Certain embodiments of the present invention provide selected compounds having a molecular structure according to Formula 1: In Formula 1, Z is —CO—, —SO—, or —SO2—; Ar is phenyl, heteroaryl, or heterocycloalkyl; Het is heteroaryl; R is R?, X, or NR1R2; R? is R3, or OR3; R? is R4, or OR4; R1 and R2 are each independently H, alkyl, or acyl; R3 is H, heteroaryl, or alkyl; R4 is H, heteroaryl, or CnH2n+1 (n>2); and X is F, Br, I, CN, or NO2. In some embodiments, compounds having a molecular structure according to Formula 1 have the property of inhibiting a growth of a cell line selected from HeLa and MB468 with a sub-micromolar IC50.

Abstract: A seat device with sucking base for tool is provided, including an inserting column and a sucking portion. The inserting column has an inserting portion formed with at least one inserting hole, and each inserting hole is provided for at least one rod-shaped tool to insert therein. The sucking portion is disposed at an end of the inserting column opposite to the inserting portion. The sucking portion has a concave sucking face, and none of the at least one inserting hole is open on the sucking face.

Abstract: The present invention relates to novel TMPK inhibitor compositions and their methods of use. In particular, it relates to novel TMPK inhibitor compositions and therapeutics that lead to dUTP-mediated DNA repair in tumor cells and acts as a novel chemosensitizer, which are useful in methods for treating or preventing cancers.

Abstract: A method and associated systems for representing multidimensionality of a data table by combining a first set of data elements, units, or cells of the table into a multidimensional, expandable, second data unit. One or more processors of a computer system: determine a set of a first data units to be combined; determine a type of multidimensionality of the second data unit after combination; and combine, as a function of the type of multidimensionality, the first set of the first data units into the second data unit. The type of multidimensionality may be horizontal, vertical, or higher-dimensional (that is, greater than two-dimensional) dimensionality.

Abstract: Certain embodiments of the present invention provide selected compounds having a molecular structure according to Formula 1: In Formula 1, Z is —CO—, —SO—, or —SO2—; Ar is phenyl, heteroaryl, or heterocycloalkyl; Het is heteroaryl; R is R?, X, or NR1R2; R? is R3, or OR3; R? is R4, or OR4; R1 and R2 are each independently H, alkyl, or acyl; R3 is H, heteroaryl, or alkyl; R4 is H, heteroaryl, or CnH2n+1 (n>2); and X is F, Br, I, CN, or NO2. In some embodiments, compounds having a molecular structure according to Formula 1 have the property of inhibiting a growth of a cell line selected from HeLa and MB468 with a sub-micromolar IC50.

Abstract: A retained needle structure of a comprises a syringe needle with one or more fastening portion, a catheter with a cannula having a flexible tube, as well as a syringe cover with an aperture and gliding portion. The syringe needle has an inserting portion which is axially operated by users to enhance safety practice in clinical use. First design is the sliding slot has a deflected slant portion at the distal end. When the fastening portion is at the rear end of sliding slot, the injection needle is already inside of syringe cover. At the same point, body of the syringe needle is deflected laterally from the center of the syringe cover. The second design is used the levering effect from gravity of syringe cover. When the fastening portion is at the rear end of sliding slot, the syringe cover is vertically rotated from the original center of the syringe cover.

Abstract: The present invention relates to novel TMPK inhibitor compositions and their methods of use. In particular, it relates to novel TMPK inhibitor compositions and therapeutics that lead to dUTP-mediated DNA repair in tumor cells and acts as a novel chemosensitizer, which are useful in methods for treating or preventing cancers.

Abstract: A chargeable case of an electronic device includes an envelop body for enveloping an electronic device therein, a receiving coil, a power output interface and a built-in AC/DC rectifying circuit. The receiving coil wirelessly receives alternating current from a power supply device. The power output interface connects a power input interface of the electronic device. The AC/DC rectifying circuit is connected the receiving coil and the power output interface. The AC/DC rectifying circuit converts the received alternating current into direct current and supplies the direct current to the power output interface for charging the electronic device. A charging system is also disclosed.