Abstract: Pyrimidine compounds of Formula (I). Assignments to the variables in the formula are set forth herein. Also disclosed is a method of treating cancer with one of the pyrimidine compounds.

Abstract: A high-insulation multilayer planar transformer (1) includes a pair of iron cores (20) and a circuit board integration (10a). The circuit board integration (10a) is stacked between the iron cores (20) and has a through hole (100a). The circuit board integration (10a) includes a first to a third insulating layers (11a, 12a, 14a) and a first to a second coil windings (13a, 15a). The first and third insulating layers (11a, 14a) include at least two insulating plates (111a, 141a) stacked with each other respectively. The second insulating layer (12a) includes at least one insulating plate (121a). The coil winding (13a, 15a) is disposed between the adjacent insulating layers and surrounds the through hole (100a) planarly. Therefore, the reinforced insulation requirement of safety regulations may be achieved.

Abstract: A control circuit having extended hold-up time is coupled to a bus path of a conversion circuit. The control circuit includes a bypass circuit, an energy storage capacitor, and an auxiliary power circuit. The auxiliary power circuit supplies an energy storage voltage to the energy storage capacitor according to a working voltage provided by the conversion circuit. When a bus voltage of the bus path is less than or equal to the energy storage voltage, the energy storage voltage is supplied to the bus path through the bypass circuit so that the bus voltage is greater than or equal to a predetermined voltage within a hold-up time.

Abstract: Compounds of formula (I): wherein R1, R2, R3, R4, R5, and X are defined herein. Also disclosed are pharmaceutical compositions and methods related to use of these compounds.

Abstract: Compounds of formula (I): wherein R1, R2, R3, R4, R5, and X are defined herein. Also disclosed are pharmaceutical compositions and methods related to use of these compounds.

Abstract: A system for IPsec-compliant network address port translation. The system comprises a communication unit, a storage device, and a processor. The communication unit receives an outgoing first Internet Key Exchange (IKE) packet and a first incoming Encapsulating Security Payload (ESP) packet. The IKE packet comprises an IP header specifying a private source IP address and a first destination IP address. The ESP packet comprises a first source IP address and a second destination IP address, wherein the first source IP address equals the first destination IP address. The storage device stores the private source IP address and the first destination IP address in corresponding fields of a first table. The processor, connected to the communication unit and the storage device, retrieves the first source IP address of the first ESP packet, searches the first table for a match of the first source IP address, and substitutes the searched match for the second destination IP address of the ESP packet.