Abstract: A semiconductor device includes a first semiconductor structure, a second semiconductor structure, a first isolation block and a second isolation block. The first semiconductor structure includes a first gate structure wrapping around a first sheet structures and a second sheet structures, and a first dielectric wall disposed between and separating the first and second sheet structures. The second semiconductor structure includes a second gate structure wrapping around third sheet structures. The first isolation block is disposed on the first dielectric wall of the first semiconductor structure and separates the first gate structure into a first gate portion wrapping around the first sheet structures and a second gate portion wrapping around the second sheet structures. The second isolation block is disposed between the first and second semiconductor structures and separates the first gate structure from the second gate structure.

Abstract: 2-hydroxy-5-[2-(4-(trifluoromethylphenyl)ethylamino)]benzoic acid crystal forms and a preparation method therefor are proposed. Crystal form I is a monoclinic crystal system, which has a Pc space group and can be obtained by slow cooling, evaporating the solvent at a constant temperature, evaporating the solvent at an increased temperature, or adding an anti-solvent. Crystal form II is a triclinic crystal system, which has a P1 space group and can be obtained by rapid cooling or freeze-drying. According to the method, the process is simple, costs are low, and the yield exceeds 90%; and the crystal forms of the crystal forms I and II have high purity, the crystal shapes thereof are intact, and have excellent fluidity, facilitating preparation, particularly the preparation of a pharmaceutical preparation for preventing and/or treating degenerative diseases of the central nervous system. Furthermore, the two crystal forms have a better apparent solubility than that of raw materials.

Abstract: A method for meat production by in vitro cell culture includes isolating tissue from an animal or plant source and making a cell suspension of cells, and growing the cells into a solid or semi-solid structure that mimics an animal organ by growing the cells on a food grade scaffold in a culture medium. Expression of one or more proteins in the growing cells may be increased by altering a level of one or more micro RNAs that regulate expression of the protein. Additionally, the growing cells may be co-cultured with bioengineered cells that secrete growth factors and cytokines that support the growth of the cells in situ. The co-culturing technique reduces or eliminates the need for animal-derived fetal bovine serum in the culture medium.

Abstract: A method for quantifying cells embedded in a scaffold, comprising the steps of (a) a lysing step to cause the cells to lyse using alkali or proteinase; (b) a purification step comprising centrifugation or a series of elution; and (c) a quantification step comprising the steps of (i) simultaneously carrying out probe-based qPCR on a sample reaction mix and a plurality of reference reaction mixes; (ii) collecting the signals from the probe-based qPCR products from the sample reaction mix and reference reaction mix; (iii) creating a standard curve based on the collected signals from the reference reaction mixes; and (iv) deducing the number of cells in the sample through the standard curve.

Abstract: A voltage detection device is provided. The voltage detection device includes a first voltage divider circuit, a comparison circuit, and a second voltage divider circuit. The first voltage divider circuit is configured to receive an input voltage and output a comparison voltage according to the input voltage. The comparison circuit is configured to receive the comparison voltage to compare the comparison voltage with a reference voltage and determine whether to change a trigger signal according to a comparison result. The second voltage divider circuit is configured to receive the input voltage. When the input voltage is greater than or equal to a predetermined voltage value, the second voltage divider circuit and the first voltage dividing circuit form a parallel structure to pull down the comparison voltage.

Abstract: A method for preparing 2-hydroxy-5-[2-(4-(trifluoromethylphenyl)ethylamino)]benzoic acid is proposed. The method may include protection, condensation, and hydrolysis. By means of the screening of a hydroxyl protecting reagent for a starting material, for example, 2-(4-trifluoromethyl)phenethylalcohol and the optimization of other process parameters, the contents of meta-isomer impurities and disubstituted impurities in a target product are effectively controlled. Accordingly, the quality of the product is significantly improved, the reaction yield is also greatly improved, and the improved product quality can satisfy related requirements of preparation research.

Abstract: The present invention relates to pharmaceutical compositions and methods for treating ischemic stroke in humans, using a tetrafluorobenzyl derivative of formula (I) or a pharmaceutically acceptable salt thereof conjointly with a thrombolytic drug, endovascular thrombectomy, or both (e.g., endovascular thrombectomy and a thrombolytic drug). Administration of a tetrafluorobenzyl derivative of formula (I) or its pharmaceutically acceptable salt can reduce reperfusion injury and other adverse events in patients conjointly receiving a thrombolytic drug, endovascular thrombectomy, or endovascular thrombectomy with a thrombolytic drug.

Abstract: The present invention relates to pharmaceutical compositions and methods for treating ischemic stroke in humans, using a tetrafluorobenzyl derivative of formula (I) or a pharmaceutically acceptable salt thereof conjointly with a thrombolytic drug, endovascular thrombectomy, or both (e.g., endovascular thrombectomy and a thrombolytic drug). Administration of a tetrafluorobenzyl derivative of formula (I) or its pharmaceutically acceptable salt can reduce reperfusion injury and other adverse events in patients conjointly receiving a thrombolytic drug, endovascular thrombectomy, or endovascular thrombectomy with a thrombolytic drug.

Abstract: A power supply phase doubling system includes a pulse width modulation (PWM) controller and first and second phase doubling chips. The PWM controller outputs a PWM signal. The first phase doubling chip is operated at a power supply voltage and has a first PWM output pin to generate a first control signal and a second control signal according to the PWM signal, and generates a first output signal according to the first control signal. The second phase doubling chip is operated at the power supply voltage, has a second PWM output pin, and is configured to generate a second output signal according to the second control signal. The first and second phase doubling chips are respectively switched between a master mode and a slave mode according to a voltage level of the first PWM output pin and a voltage level of the second PWM output pin.

Abstract: The present invention relates to pharmaceutical compositions and methods useful for treating pulmonary disorders, including asthma, chronic obstructive pulmonary disease (COPD), asthma-COPD overlap syndrome (ACOD), or any other respiratory diseases comprising 2-hydroxybenzoic acid derivatives of the formula (I) or a pharmaceutically acceptable salt thereof. Administration of a 2-hydroxybenzoic acid derivative of formula (I) significantly alleviates airway tissue damage and inflammation in animal models of asthma and COPD.

Abstract: An integrated chip having an integrated function capable of providing cell image and biochemical detection is provided and includes a sequentially stacked and sealed laminate set. The laminate set includes an upper laminate, a middle laminate and a lower laminate. The upper laminate composed of one or more plates and having one or more holes for sample injection and sample or air discharging of. The middle laminate composed of one or more plates includes at least two hollow structures that define an imaging chamber and a biochemical detection area. The lower laminate includes at least one filtering element and at least one electrode sensing element disposed in the biochemical detection. The filtering element is for blocking suspended particles, and the electrode sensing element has electrode terminals for connecting to instruments or equipment to perform the measurements and analysis of electrochemistry and impedance.

Abstract: Disclosed is an optical system using image restoration, including a light source, a pinhole, a testing platform, an image sensor and an image processing device. The pinhole is disposed on a light transmission path of the light source. The testing platform is disposed on the light transmission path of the light source and the pinhole is located between the light source and the testing platform. The testing platform is used to place a testing sample. The image sensor is disposed below the testing platform, and used to sense the testing sample so as to output an optical diffraction signal. The image processing device is electrically connected to the image sensor and used to perform signal processing and optical signal recognition on the optical diffraction signal of the testing sample so as to obtain a clear image of the testing sample.

Abstract: A high throughput lensless imaging method and system thereof are provided. The system mainly includes a light source, an optical panel, and an optical image sensing module. The light source is used to generate light with a specific wavelength to illuminate. The optical panel corresponds to the light source and includes an optical pinhole that corresponds to the light source such that the light generated by the light source passes through the optical pinhole. The position of the optical image sensing module corresponds to the other surface of the optical panel, and the optical image sensing module includes a sensing unit to receive an optical diffraction signal formed after the light source illuminates an object. The sensing unit is electrically connected to a computing unit that is used to compute after receiving the optical diffraction signal transmitted by the sensing unit, so as to perform the computation and reconstruction of an image.

Abstract: The present invention relates to pharmaceutical compositions and methods for treating ischemic stroke in humans, using a tetrafluorobenzyl derivative of formula (I) or a pharmaceutically acceptable salt thereof conjointly with a thrombolytic drug, endovascular thrombectomy, or both (e.g., endovascular thrombectomy and a thrombolytic drug). Administration of a tetrafluorobenzyl derivative of formula (I) or its pharmaceutically acceptable salt can reduce reperfusion injury and other adverse events in patients conjointly receiving a thrombolytic drug, endovascular thrombectomy, or endovascular thrombectomy with a thrombolytic drug.

Abstract: A voltage converter is provided. The voltage converter includes a charge pump and a switching circuit. The charge pump includes an input capacitor, where two ends of the input capacitor are electrically connected to an input end and a ground end respectively. The switching circuit includes a first switch, a second switch, a third switch, and a fourth switch, and these switches are connected in series. The first switch is electrically connected to the input end, the fourth switch is electrically connected to the ground end, a capacitor is connected in parallel with the second switch and the third switch, and an output end is electrically connected between the second switch and the third switch.

Abstract: A method for manufacturing a bicycle wheel rim includes: (a) providing a first mold assembly which includes an inner mold and an outer mold, the outer mold having an annular first forming face to surround an annular second forming face of the inner mold; (b) disposing annularly a first prepreg preform that overlie annularly and respectively the annular first and second forming faces; (c) causing the first and second forming faces to press the concaved faces and thermoforming the first prepreg preform to obtain an annular outer rim part; (d) forming a second prepreg preform into an annular inner rim part; and (e) combining the annular outer rim part with the annular inner rim part to form a wheel rim.

Abstract: The present invention relates to a pharmaceutical composition useful for treating or preventing inflammatory disease and cell damage, and a method for treating or preventing inflammatory disease and cell damage. The present invention uses the 2-hydroxybenzoic acid derivative represented by the specific chemical formula or its pharmaceutically acceptable salt. The compound of the present invention is useful for treating or preventing cell damage and inflammatory disease including gastritis, gastric ulcer, pancreatitis, colitis, arthritis, diabetes, arteriosclerosis, nephritis, hepatitis, Alzheimer's disease, Parkinson's disease and Lou Gehrig's disease.

Abstract: The present invention relates to a pharmaceutical composition useful for treating or preventing inflammatory disease and cell damage, and a method for treating or preventing inflammatory disease and cell damage. The present invention uses the 2-hydroxybenzoic acid derivative represented by the specific chemical formula or its pharmaceutically acceptable salt. The compound of the present invention is useful for treating or preventing cell damage and inflammatory disease including gastritis, gastric ulcer, pancreatitis, colitis, arthritis, diabetes, arteriosclerosis, nephritis, hepatitis, Alzheimer's disease, Parkinson's disease and Lou Gehrig's disease.

Abstract: The present invention relates to a pharmaceutical composition useful for treating or preventing inflammatory disease and cell damage, and a method for treating or preventing inflammatory disease and cell damage. The present invention uses the 2-hydroxybenzoic acid derivative represented by the specific chemical formula or its pharmaceutically acceptable salt. The compound of the present invention is useful for treating or preventing cell damage and inflammatory disease including gastritis, gastric ulcer, pancreatitis, colitis, arthritis, diabetes, arteriosclerosis, nephritis, hepatitis, Alzheimer's disease, Parkinson's disease and Lou Gehrig's disease.

Abstract: A transient voltage compensation apparatus and a power supply using the same are provided. The power supply mainly uses a compensation circuit coupled between an input terminal and an output terminal of a power converter. When a load of the power supply is switched in a very short time, a power coupled to the compensation circuit is retrieved to compensate the output of the power supply, such that the output voltage is kept steady, and the transient response of the power supply is increased.