Patents by Inventor Chun-Su Yuan

Chun-Su Yuan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PARTICLES CONTAINING AN OPIOID RECEPTOR ANTAGONIST AND METHODS OF USE
    Publication number: 20200101026
    Abstract: Particles comprising an opioid receptor antagonist as well as methods of their use and methods of their preparation are provided herein. Such particles may be used for treating and preventing opioid-induced side effects in patients, and may be provided to chronic opioid users as well.
    Type: Application
    Filed: December 4, 2019
    Publication date: April 2, 2020
    Inventor: Chun-Su YUAN
  • Particles containing an opioid receptor antagonist and methods of use
    Patent number: 10507188
    Abstract: Particles comprising an opioid receptor antagonist as well as methods of their use and methods of their preparation are provided herein. Such particles may be used for treating and preventing opioid-induced side effects in patients, and may be provided to chronic opioid users as well.
    Type: Grant
    Filed: December 7, 2017
    Date of Patent: December 17, 2019
    Assignee: The University of Chicago
    Inventor: Chun-Su Yuan
  • PARTICLES CONTAINING AN OPIOID RECEPTOR ANTAGONIST AND METHODS OF USE
    Publication number: 20180098947
    Abstract: Particles comprising an opioid receptor antagonist as well as methods of their use and methods of their preparation are provided herein. Such particles may be used for treating and preventing opioid-induced side effects in patients, and may be provided to chronic opioid users as well.
    Type: Application
    Filed: December 7, 2017
    Publication date: April 12, 2018
    Inventor: Chun-Su Yuan
  • USE OF OPIOID ANTAGONISTS TO ATTENUATE ENDOTHELIAL CELL PROLIFERATION AND MIGRATION
    Publication number: 20170252336
    Abstract: The invention provides methods of attenuating, e.g., inhibiting or reducing, cellular proliferation and migration, particularly endothelial cell proliferation and migration, including that associated with angiogenesis, using opioid antagonists, including, but not limited to, those that are peripherally restricted antagonists.
    Type: Application
    Filed: May 17, 2017
    Publication date: September 7, 2017
    Inventors: Jonathan Moss, Mark Lingen, Patrick A. Singleton, Joe G.N. Garcia, Chun-Su Yuan
  • Use of opioid antagonists to attenuate endothelial cell proliferation and migration
    Patent number: 9675602
    Abstract: The invention provides methods of attenuating, e.g., inhibiting or reducing, cellular proliferation and migration, particularly endothelial cell proliferation and migration, including that associated with angiogenesis, using opioid antagonists, including, but not limited to, those that are peripherally restricted antagonists.
    Type: Grant
    Filed: August 21, 2013
    Date of Patent: June 13, 2017
    Assignee: THE UNIVERSITY OF CHICAGO
    Inventors: Jonathan Moss, Mark Lingen, Patrick A. Singleton, Joe G. N. Garcia, Chun-Su Yuan
  • Use of opioid antagonists to attenuate endothelial cell proliferation and migration
    Patent number: 9662325
    Abstract: The invention provides methods of attenuating, e.g., inhibiting or reducing, cellular proliferation and migration, particularly endothelial cell proliferation and migration, including that associated with angiogenesis, using opioid antagonists, including, but not limited to, those that are peripherally restricted antagonists.
    Type: Grant
    Filed: May 30, 2014
    Date of Patent: May 30, 2017
    Assignee: THE UNIVERSITY OF CHICAGO
    Inventors: Jonathan Moss, Mark Lingen, Patrick A. Singleton, Joe G. N. Garcia, Chun-Su Yuan
  • BIOAVAILABILITY OF ORAL METHYLNALTREXONE INCREASES WITH A PHOSPHATIDYLCHOLINE-BASED FORMULATION
    Publication number: 20150190523
    Abstract: A pharmaceutical composition comprising a phosphatidylcholine-based opioid receptor antagonist formulation, as well as methods of their use and methods of their preparation are provided herein. Such pharmaceutical composition may be used for treating and preventing opioid-induced side effects in patients, and may be provided to chronic opioid users as well.
    Type: Application
    Filed: March 13, 2013
    Publication date: July 9, 2015
    Inventors: Chun-Su Yuan, Chong-Zhi Wang, Maojian Gu, Dong-Hai Lin
  • USE OF OPIOID ANTAGONISTS TO ATTENUATE ENDOTHELIAL CELL PROLIFERATION AND MIGRATION
    Publication number: 20140323426
    Abstract: The invention provides methods of attenuating, e.g., inhibiting or reducing, cellular proliferation and migration, particularly endothelial cell proliferation and migration, including that associated with angiogenesis, using opioid antagonists, including, but not limited to, those that are peripherally restricted antagonists.
    Type: Application
    Filed: May 30, 2014
    Publication date: October 30, 2014
    Inventors: Jonathan Moss, Mark Lingen, Patrick A. Singleton, Joe G.N. Garcia, Chun-Su Yuan
  • USE OF OPIOID ANTAGONISTS TO ATTENUATE ENDOTHELIAL CELL PROLIFERATION AND MIGRATION
    Publication number: 20140066467
    Abstract: The invention provides methods of attenuating, e.g., inhibiting or reducing, cellular proliferation and migration, particularly endothelial cell proliferation and migration, including that associated with angiogenesis, using opioid antagonists, including, but not limited to, those that are peripherally restricted antagonists.
    Type: Application
    Filed: August 21, 2013
    Publication date: March 6, 2014
    Applicant: The University of Chicago
    Inventors: Jonathan Moss, Mark Lingen, Patrick A. Singleton, Joe G.N. Garcia, Chun-Su Yuan
  • Use of opioid antagonists to attenuate endothelial cell proliferation and migration
    Patent number: 8524731
    Abstract: The invention provides methods of attenuating, e.g., inhibiting or reducing, cellular proliferation and migration, particularly endothelial cell proliferation and migration, including that associated with angiogenesis, using opioid antagonists, including, but not limited to, those that are peripherally restricted antagonists.
    Type: Grant
    Filed: April 17, 2006
    Date of Patent: September 3, 2013
    Assignee: The University of Chicago
    Inventors: Jonathan Moss, Mark Lingen, Patrick A. Singleton, Joe G. N. Garcia, Chun-Su Yuan
  • USE OF METHYLNALTREXONE AND RELATED COMPOUNDS TO TREAT CONSTIPATION IN CHRONIC OPIOID USERS
    Publication number: 20120277260
    Abstract: A method of preventing or treating constipation in a patient who has been chronically taking opioids, the method comprising administering a quaternary derivative of noroxymorphone in an amount sufficient to prevent or treat the side effect in the patient, but which amount would be insufficient to treat a patient with the same opioid-induced side effect who had not chronically been administered opioids.
    Type: Application
    Filed: June 26, 2012
    Publication date: November 1, 2012
    Applicant: The University of Chicago
    Inventors: Joseph F. Foss, Michael F. Roizen, Jonathan Moss, Chun-Su Yuan, William Drell
  • USE OF METHYLNALTREXONE AND RELATED COMPOUNDS TO TREAT CONSTIPATION IN CHRONIC OPIOID USERS
    Publication number: 20120190702
    Abstract: A method of preventing or treating constipation in a patient who has been chronically taking opioids, the method comprising administering a quaternary derivative of noroxymorphone in an amount sufficient to prevent or treat the side effect in the patient, but which amount would be insufficient to treat a patient with the same opioid-induced side effect who had not chronically been administered opioids.
    Type: Application
    Filed: September 12, 2011
    Publication date: July 26, 2012
    Applicant: The University of Chicago
    Inventors: Joseph F. FOSS, Michael F. ROIZEN, Jonathan MOSS, Chun-Su YUAN, William DRELL
  • PARTICLES CONTAINING AN OPIOID RECEPTOR ANTAGONIST AND METHODS OF USE
    Publication number: 20110250278
    Abstract: Particles comprising an opioid receptor antagonist as well as methods of their use and methods of their preparation are provided herein. Such particles may be used for treating and preventing opioid-induced side effects in patients, and may be provided to chronic opioid users as well.
    Type: Application
    Filed: June 15, 2009
    Publication date: October 13, 2011
    Applicant: University of Chicago
    Inventor: Chun-Su Yuan
  • USE OF METHYLNALTREXONE AND RELATED COMPOUND TO TREAT CONSTIPATION IN CHRONIC OPIOID USERS
    Publication number: 20100087472
    Abstract: A method of preventing or treating constipation in a patient who has been chronically taking opioids, the method comprising administering a quaternary derivative of noroxymorphone in an amount sufficient to prevent or treat the side effect in the patient, but which amount would be insufficient to treat a patient with the same opioid-induced side effect who had not chronically been administered opioids.
    Type: Application
    Filed: June 30, 2009
    Publication date: April 8, 2010
    Inventors: Joseph F. Foss, Michael F. Roizen, Jonathan Moss, Chun-Su Yuan, William Drell
  • USE OF METHYLNALTREXONE AND RELATED COMPOUNDS FOR TREATMENT OF GASTROINTESTINAL DYSFUNCTION INDUCED BY ENDOGENOUS OPIOIDS
    Publication number: 20090312359
    Abstract: A method of for preventing or treating gastrointestinal dysfunction and constipation caused by endogenous opioids in a patient who has been chronically taking opioids. The method comprises administering methylnaltrexone or another quaternary derivative of noroxymorphone most preferably by parenteral, intramuscular, intravenous or oral route.
    Type: Application
    Filed: December 12, 2008
    Publication date: December 17, 2009
    Inventors: Joseph F. Foss, Michael F. Roizen, Jonathan Moss, Chun-Su Yuan, William Drell
  • USE OF OPIOID ANTAGONISTS TO ATTENUATE ENDOTHELIAL CELL PROLIFERATION AND MIGRATION
    Publication number: 20060258696
    Abstract: The invention provides methods of attenuating, e.g., inhibiting or reducing, cellular proliferation and migration, particularly endothelial cell proliferation and migration, including that associated with angiogenesis, using opioid antagonists, including, but not limited to, those that are peripherally restricted antagonists.
    Type: Application
    Filed: April 17, 2006
    Publication date: November 16, 2006
    Inventors: Jonathan Moss, Mark Lingen, Patrick Singleton, Joe Garcia, Chun-Su Yuan
  • Use of methylnaltrexone and related compounds
    Publication number: 20050048117
    Abstract: A composition for preventing or treating the opioid induced side effect, inhibition of gastrointestinal motility is disclosed. The composition comprises methylnaltrexone or another quaternary derivative of noroxymorphone administered to a patient prior to the administration of an opioid or after the onset of side effects induced by the administration of an opioid, wherein the methylnaltrexone or quaternary derivative is administered orally in an enterically coated form.
    Type: Application
    Filed: October 12, 2004
    Publication date: March 3, 2005
    Inventors: Joseph Foss, Michael Roizen, Jonathan Moss, Chun-Su Yuan, William Drell
  • Oral use of methylnaltrexone and related compounds to treat constipation in chronic opioid users
    Publication number: 20040167148
    Abstract: A method of treating constipation in a patient who has been chronically taking opioids, the method comprising orally administering a quaternary derivative of noroxymorphone in an amount sufficient to achieve laxation.
    Type: Application
    Filed: February 24, 2004
    Publication date: August 26, 2004
    Inventors: Joseph F. Foss, Michael F. Roizen, Jonathan Moss, Chun-Su Yuan, William Drell
  • Oral use of methylnaltrexone and related compounds to induce laxation in chronic opioid users
    Publication number: 20040167147
    Abstract: A method of inducing Taxation in a patient who has been chronically taking opioids, the method comprising orally administering a quaternary derivative of noroxymorphone in an sufficient amount.
    Type: Application
    Filed: February 24, 2004
    Publication date: August 26, 2004
    Inventors: Joseph F. Foss, Michael F. Roizen, Jonathan Moss, Chun-Su Yuan, William Drell
  • Use of methylnaltrexone and related compounds to induce laxation in chronic opioid users
    Publication number: 20040162307
    Abstract: A method of inducing laxation in a patient who has been chronically taking opioids, the method comprising administering a quaternary derivative of noroxymorphone in an amount sufficient to prevent or treat the side effect in the patient, but which amount would be insufficient to treat a patient with the same opioid-induced side effect who had not chronically been administered opioids.
    Type: Application
    Filed: February 12, 2004
    Publication date: August 19, 2004
    Inventors: Joseph F. Foss, Michael F. Roizen, Jonathan Moss, Chun-Su Yuan, William Drell