Abstract: The present invention provides methods for characterizing obstructive sleep apnea (OSA) patients in the treatment of OSA, and devices thereof. The methods comprise measuring polysomnography of said patients; analyzing polysomnography, and determining a characteristic of the polysomnography and selections of suitable treatments based on the patterns.

Abstract: Systems and methods are provided for percutaneously suturing tissue. An elongated deployment member having a guide member coaxially disposed over a shaft member may be used to carry a needle deployment member. The needle deployment member may be carried at a distal end of the elongated deployment member and include a plurality of needles releasably secured to the needle deployment member, wherein each needle is routed coaxially within the distal end of the needle deployment member. The needle deployment member may further include a needle pusher driven by a link coaxially disposed within the shaft member, wherein the needle pusher is configured to advance each needle through the distal end of the needle deployment member and coaxially over the proximal end of the needle deployment member to position the plurality of needles at a piercing angle in a proximal direction.

Abstract: A system configured to perform power normalization for voice enhancement. The system may identify active intervals corresponding to voice activity and may selectively amplify the active intervals in order to generate output audio data at a near uniform loudness. The system may determine a variable gain for each of the active intervals based on a desired output loudness and a flatness value, which indicates how much a signal envelope is to be modified. For example, a low flatness value corresponds to no modification, with peak active interval values corresponding to the desired output loudness and lower active intervals being lower than the desired output loudness. In contrast, a high flatness value corresponds to extensive modification, with peak active interval values and lower active interval values both corresponding to the desired output loudness. Thus, individual words may share the same peak power level.

Abstract: A method and apparatus for the detection, analysis, and identification of realistic human body and limb movements during sports actions for multiple uses comprises collecting the health information of the move, using the moves as a training and monitoring techniques in live usage settings, and as inputs to simulators and video game environments. At least one body-worn sensor transmits values wirelessly to a computing device that records the moves and calculates the health statistics then uses a machine-learning algorithm to analyze and identify the moves. These algorithms then output information and can simulate realistic moves, identify how far from these realistic moves the actual move is, and apply these moves to an electronic game. These algorithms, through various techniques, can distinguish movements, identify many different fine-grain movements, and enforce the full completion of these moves before registering them, thus preventing cheating in a realistic gaming scenario.

Abstract: Systems and methods are provided for suturing tissue. An elongated deployment shaft carries a needle deployment assembly with needles carrying suture material. A needle catcher is disposed over the shaft and configured to engage and retain at least a portion of each of the needles carrying the suture material when the needles are passed through the tissue to be sutured to a proximal position.

Abstract: Systems and methods are provided for suturing tissue. An elongated deployment shaft carries a needle deployment assembly with needles carrying suture material and a stabilizer that is reconfigurable between an unexpanded insertion profile and an expanded profile. A catcher tube over the shaft having a catcher at a distal end may retain at least a portion of the needles carrying the suture material when the needles are passed through the tissue to be sutured into engagement with the catcher. A sheath over the catcher tube may sandwich tissue to be sutured against the stabilizer when expanded under control of first actuator. A second actuator may control the needles.

Abstract: The present invention discloses a negative-pressure oral apparatus capable of relieving discomfort of soft tissues in the oral cavity and improving fixation of the oral apparatus to prevent the oral apparatus from falling off due to mouth opening. The oral apparatus is compact and elastic so that it fits various shapes and sizes of the oral cavity and is easy to be put on and taken off to provide convenience and safety to the user. In another embodiment, a method for maintaining a negative oral pressure and collecting liquid by coupling the oral apparatus to a liquid collecting apparatus capable of effectively providing the oral cavity with a negative pressure to expel liquid in the oral apparatus and deliver the liquid to an absorbing element in the liquid collecting apparatus so as to prevent liquid leakage or contamination.

Abstract: An oral negative-pressure therapy system includes a container and absorbent insert for the container. The container includes a baffle inside an interior of the container. A fluid passageway extends along the baffle for delivering fluid (e.g., a mixture of air and saliva) into the container. The absorbent insert for absorbing liquid (e.g., saliva) in the container may is over the baffle. At least one of the baffle and the absorbent insert is configured to maintain a fluid flow path between the baffle and the absorbent insert to maintain fluid communication between a fluid inlet and a fluid outlet of the container. The absorbent insert and/or the container may be designed and constructed to burst air bubbles in the aspirated liquid. In one or more embodiments, the absorbent insert is replaceable so that a spent absorbent insert can be replaced with a new, fresh absorbent insert.

Abstract: The present invention provides a negative pressure generator comprising a vacuum pump having an intake end and an exhaust end, a soundproofing module having a compartment for accommodating the vacuum pump, the soundproofing module being configured to insulate noise and vibration generated when the vacuum pump is in operation, and a silencing tube module comprising a flexible intake tube having one open end communicating with the intake end of the vacuum pump and a flexible exhaust tube having one open end communicating with the exhaust end of the vacuum pump, the silencing tube module being configured to reduce noise generated at the intake end and/or the exhaust end of the vacuum pump when the vacuum pump is in operation. The negative pressure generator can provide a vacuum source to an oral interface device to favorably create a negative pressure environment in a user's oral cavity so that the patency of the user's upper airway is maintained.

Abstract: This invention provides an oral interface mainly including a connecting channel, a collapsible chamber and a non-collapsible structure disposed inside the collapsible chamber. The connecting channel communicates between the collapsible chamber and a negative source. When a negative pressure environment is generated inside the collapsible chamber via being pumped by the negative pressure source, the non-collapsible structure supports the collapsible chamber so that there are fluid channels formed inside the collapsible chamber. The air inside a user's oral cavity can be pumped out via the fluid channels and the connecting channel. A negative pressure environment is hence formed inside the user's oral cavity.

Abstract: This invention provides an oral apparatus and method capable of alleviating or curing snore and obstructive sleep apnea by applying a negative pressure through a mini oral interface to the oral cavity. The mini oral interface creates a secure connection between the interface and mouth or teeth and prevents the interface from falling off. The oral interface also provides fixation between upper and lower lips (or tooth) and prevents opening of patient's mouth during sleeping. The negative pressure pulls the tongue toward upper palate and also pulls the soft palate forward as well. By moving the tongue and the soft palate in a forward direction, the patentcy of the upper airway near the pharynx is maintained to prevent sleep-disordered breathing. The negative pressure will pull the lips inward to close the mouth ad prevent air from entering the oral cavity from atmosphere.

Abstract: A system configured to improve speech quality by performing residual echo suppression (RES). The system may detect when double-talk conditions are present in individual frequency bands during a voice conversation and may determine gain values for the individual frequency bands. The system may determine whether double-talk conditions are present based on a normalized cross power spectral density function in a frequency domain. If double-talk conditions are present in a frequency band or far end energy is low, the system may determine a gain value that passes audio data in the frequency band, whereas if double-talk conditions are not present, the system may determine a gain value that attenuates audio data in the frequency band. The system may determine binary gain values using a decision threshold value or continuous gain values using a mapping function. The system may control an amount of suppression by selecting different mapping functions and/or parameters.

Abstract: Die cracking of a three dimensional memory device may be reduced by adding offsets to backside contact via structures. Each backside contact via structure can include laterally extending portions that extend along a first horizontal direction adjoined by adjoining portions that extend along a horizontal direction other than the first horizontal direction. In order to preserve periodicity of memory stack structures extending through an alternating stack of insulating layers and electrically conductive layers, the distance between an outermost row of a string of memory stack structures between a pair of backside contact via structures and a most proximal backside contact via structure can vary from a laterally extending portion to another laterally extending portion within the most proximal backside contact via structure. Source shunt lines that are parallel to bit lines can be formed over a selected subset of offset portions of the backside contact via structures.

Abstract: The present invention discloses a negative-pressure oral apparatus capable of relieving discomfort of soft tissues in the oral cavity and improving fixation of the oral apparatus to prevent the oral apparatus from falling off due to mouth opening. The oral apparatus is compact and elastic so that it fits various shapes and sizes of the oral cavity and is easy to be put on and taken off to provide convenience and safety to the user. In another embodiment, a method for maintaining a negative oral pressure and collecting liquid by coupling the oral apparatus to a liquid collecting apparatus capable of effectively providing the oral cavity with a negative pressure to expel liquid in the oral apparatus and deliver the liquid to an absorbing element in the liquid collecting apparatus so as to prevent liquid leakage or contamination.

Abstract: Memory openings and support openings can be formed through an alternating stack of insulating layers and sacrificial material layers. A set of dielectric layers and at least one semiconductor material layer can be sequentially deposited in each of the memory openings and the support openings. The at least one semiconductor material layer is removed from inside the support openings, while the at least one semiconductor material layer is not removed from inside the memory openings. Memory stack structures and support pillar structures are formed in the memory openings and the support openings, respectively. The sacrificial material layers are replaced with electrically conductive layers. Removal of the at least one semiconductor material layer from the support pillar structures reduces or eliminates leakage current through the support pillar structures.

Abstract: Memory openings and support openings can be formed through an alternating stack of insulating layers and sacrificial material layers. A set of dielectric layers and at least one semiconductor material layer can be sequentially deposited in each of the memory openings and the support openings. The at least one semiconductor material layer is removed from inside the support openings, while the at least one semiconductor material layer is not removed from inside the memory openings. Memory stack structures and support pillar structures are formed in the memory openings and the support openings, respectively. The sacrificial material layers are replaced with electrically conductive layers. Removal of the at least one semiconductor material layer from the support pillar structures reduces or eliminates leakage current through the support pillar structures.

Abstract: A three-dimensional memory device includes a plurality of planes, each having a respective alternating stack, strings of memory stack structures which extends through the respective alternating stack, and backside contact via structures vertically extending through the respective alternating stack, extending generally along the first horizontal direction, and laterally separating neighboring pairs of strings of memory stack structures along a second horizontal direction. A first plane includes a first plurality of strings that are laterally spaced apart along the second horizontal direction by a first plurality of backside contact via structures.

Abstract: A three-dimensional memory device includes a plurality of planes, each having a respective alternating stack, strings of memory stack structures which extends through the respective alternating stack, and backside contact via structures vertically extending through the respective alternating stack, extending generally along the first horizontal direction, and laterally separating neighboring pairs of strings of memory stack structures along a second horizontal direction. A first plane includes a first plurality of strings that are laterally spaced apart along the second horizontal direction by a first plurality of backside contact via structures.

Abstract: Die cracking of a three dimensional memory device may be reduced by adding offsets to backside contact via structures. Each backside contact via structure can include laterally extending portions that extend along a first horizontal direction adjoined by adjoining portions that extend along a horizontal direction other than the first horizontal direction. In order to preserve periodicity of memory stack structures extending through an alternating stack of insulating layers and electrically conductive layers, the distance between an outermost row of a string of memory stack structures between a pair of backside contact via structures and a most proximal backside contact via structure can vary from a laterally extending portion to another laterally extending portion within the most proximal backside contact via structure. Source shunt lines that are parallel to bit lines can be formed over a selected subset of offset portions of the backside contact via structures.