Patents by Inventor Chung-Jen James Chou

Chung-Jen James Chou has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BI-FUNCTIONAL ARGININE-GLYCINE-ASPARTIC ACID (RGD) PEPTIDES AND METHODS TO PROMOTE ANGIOGENESIS
    Publication number: 20210405064
    Abstract: The present invention provides an in vitro method for identifying a compound that promotes endothelial cell adhesion, endothelial cell spreading, endothelial cell migration and/or endothelial cell proliferation for the manufacture of a diagnostic or therapeutic agent. The present invention further provides the identified compounds and pharmaceutical compositions, and assays and kits for identifying a compound or using a compound that promotes endothelial cell adhesion, endothelial cell spreading, endothelial cell migration and/or endothelial cell proliferation and is useful for bioprinting.
    Type: Application
    Filed: September 16, 2021
    Publication date: December 30, 2021
    Inventors: Ying Mei, Jia Jia, Chung-Jen James Chou
  • Bi-functional arginine-glycine-aspartic acid (RGD) peptides and methods to promote angiogenesis
    Patent number: 11150251
    Abstract: The present invention provides an in vitro method for identifying a compound that promotes endothelial cell adhesion, endothelial cell spreading, endothelial cell migration and/or endothelial cell proliferation for the manufacture of a diagnostic or therapeutic agent. The present invention further provides the identified compounds and pharmaceutical compositions, and assays and kits for identifying a compound or using a compound that promotes endothelial cell adhesion, endothelial cell spreading, endothelial cell migration and/or endothelial cell proliferation and is useful for bioprinting.
    Type: Grant
    Filed: October 6, 2017
    Date of Patent: October 19, 2021
    Assignees: Clemson University Research Foundation, MUSC Foundation for Research Development
    Inventors: Ying Mei, Jia Jia, Chung-Jen James Chou
  • Histone deacetylase inhibitors and uses thereof
    Patent number: 10870618
    Abstract: Provided herein are compounds of the formula (I) as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of cancer.
    Type: Grant
    Filed: October 13, 2017
    Date of Patent: December 22, 2020
    Assignee: MUSC FOUNDATION FOR RESEARCH DEVELOPMENT
    Inventors: Chung-Jen James Chou, Jesse McClure, Cheng Zhang, Elizabeth Inks
  • HDAC inhibitors and uses thereof
    Patent number: 10703737
    Abstract: The present invention relates to histone deacetylase inhibitors, and to pharmaceutical compositions comprising the compounds, useful for the treatment of ischemia-reperfusion injury and for cardioprotection.
    Type: Grant
    Filed: March 13, 2019
    Date of Patent: July 7, 2020
    Assignee: MUSC FOUNDATION FOR RESEARCH DEVELOPMENT
    Inventors: Donald R. Menick, Chung-Jen James Chou, Daniel Herr, Xiaoyang Li
  • HISTONE DEACETYLASE INHIBITORS AND USES THEREOF
    Publication number: 20190308932
    Abstract: Provided herein are compounds of the formula (I) as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of cancer.
    Type: Application
    Filed: October 13, 2017
    Publication date: October 10, 2019
    Inventors: Chung-Jen James CHOU, Jesse McClure, Cheng ZHANG, Elizabeth INKS
  • HDAC INHIBITORS AND USES THEREOF
    Publication number: 20190284154
    Abstract: The present invention relates to histone deacetylase inhibitors, and to pharmaceutical compositions comprising the compounds, useful for the treatment of ischemia-reperfusion injury and for cardioprotection.
    Type: Application
    Filed: March 13, 2019
    Publication date: September 19, 2019
    Inventors: Donald R. Menick, Chung-Jen James Chou, Daniel Herr, Xiaoyang Li
  • Bi-Functional Arginine-Glycine-Aspartic Acid (RGD) Peptides and Methods to Promote Angiogenesis
    Publication number: 20180120332
    Abstract: The present invention provides an in vitro method for identifying a compound that promotes endothelial cell adhesion, endothelial cell spreading, endothelial cell migration and/or endothelial cell proliferation for the manufacture of a diagnostic or therapeutic agent. The present invention further provides the identified compounds and pharmaceutical compositions, and assays and kits for identifying a compound or using a compound that promotes endothelial cell adhesion, endothelial cell spreading, endothelial cell migration and/or endothelial cell proliferation and is useful for bioprinting.
    Type: Application
    Filed: October 6, 2017
    Publication date: May 3, 2018
    Inventors: Ying Mei, Jia Jia, Chung-Jen James Chou