Patents by Inventor Chung-Kung Lai

Chung-Kung Lai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Drug delivery system targeting to estrogen receptor over-expressed cells
    Patent number: 8128945
    Abstract: A vector for targeted delivery of drugs into estrogen receptors over-expressed cells is disclosed. The vector of the present invention is mainly about an active targeting delivery carrier which consists of a plurality of nanoparticles including: (i) a plurality of targeted moiety conjugated to the outer surface of the nanoparticles, the moiety being capable of binding with the estrogen receptor of a target cell, and (ii) bioactive agents encapsulated in the nanoparticles or forming complex with the nanoparticles. The targeted moiety of the present invention can also be conjugated to parent drugs for prodrug design.
    Type: Grant
    Filed: September 20, 2010
    Date of Patent: March 6, 2012
    Assignee: Industrial Technology Research Institute
    Inventors: Shyh-Dar Li, Ae-June Wang, Chung-Kung Lai
  • DRUG DELIVERY SYSTEM TARGETING TO ESTROGEN RECEPTOR OVER-EXPRESSED CELLS
    Publication number: 20110008262
    Abstract: A vector for targeted delivery of drugs into estrogen receptors over-expressed cells is disclosed. The vector of the present invention is mainly about an active targeting delivery carrier which consists of a plurality of nanoparticles including: (i) a plurality of targeted moiety conjugated to the outer surface of the nanoparticles, the moiety being capable of binding with the estrogen receptor of a target cell, and (ii) bioactive agents encapsulated in the nanoparticles or forming complex with the nanoparticles. The targeted moiety of the present invention can also be conjugated to parent drugs for prodrug design.
    Type: Application
    Filed: September 20, 2010
    Publication date: January 13, 2011
    Inventors: Shyh-Dar LI, Ae-June Wang, Chung-Kung Lai
  • Drug delivery system targeting to estrogen receptor over-expressed cells
    Patent number: 7820204
    Abstract: A vector for targeted delivery of drugs into estrogen receptors over-expressed cells is disclosed. The vector of the present invention is mainly about an active targeting delivery carrier which consists of a plurality of nanoparticles including: (i) a plurality of targeted moiety conjugated to the outer surface of the nanoparticles, the moiety being capable of binding with the estrogen receptor of a target cell, and (ii) bioactive agents encapsulated in the nanoparticles or forming complex with the nanoparticles. The targeted moiety of the present invention can also be conjugated to parent drugs for prodrug design.
    Type: Grant
    Filed: December 30, 2003
    Date of Patent: October 26, 2010
    Assignee: Industrial Technology Research Institute
    Inventors: Shyh-Dar Li, Ae-June Wang, Chung-Kung Lai
  • Drug delivery system targeting to estrogen receptor over-expressed cells
    Publication number: 20040166167
    Abstract: A vector for targeted delivery of drugs into estrogen receptors over-expressed cells is disclosed. The vector of the present invention is mainly about an active targeting delivery carrier which consists of a plurality of nanoparticles including: (i) a plurality of targeted moiety conjugated to the outer surface of the nanoparticles, the moiety being capable of binding with the estrogen receptor of a target cell, and (ii) bioactive agents encapsulated in the nanoparticles or forming complex with the nanoparticles. The targeted moiety of the present invention can also be conjugated to parent drugs for prodrug design.
    Type: Application
    Filed: December 30, 2003
    Publication date: August 26, 2004
    Applicant: Industrial Technology Research Institute
    Inventors: Shyh-Dar Li, Ae-June Wang, Chung-Kung Lai