Abstract: The present disclosure relates to a method for treating a cancer and/or cancer metastasis in a subject comprising administering to the subject irinotecan loaded in a mesoporous silica nanoparticle. The present disclosure also provides a conjugate comprising an agent loaded in a mesoporous silica nanoparticle (MSN) defining at least one pore and having at least one functional group on a sidewall of the at least one pore.

Abstract: A semiconductor device includes a substrate having an array region defined thereon, a ring of magnetic tunneling junction (MTJ) region surrounding the array region, a gap between the array region and the ring of MTJ region, and metal interconnect patterns overlapping part of the ring of MTJ region. Preferably, the array region includes a magnetic random access memory (MRAM) region and a logic region and the ring of MTJ region further includes a first MTJ region and a second MTJ region extending along a first direction and a third MTJ region and a fourth MTJ region extending along a second direction.

Abstract: An auxiliary determination device for evaluating whether a transcranial magnetic stimulation (TMS) is effective for a patient with depression is provided. The device includes a feature extraction unit and a machine learning unit electrically connected thereto. In an interpretation mode, the feature extraction unit extracts a feature value from electroencephalography signals of the patient, and at least a classifier of the machine learning unit determines the efficacy of TMS for the patient according to the feature value of the electroencephalography signals. The electroencephalography signals are electroencephalography signals of the patient after being driven by a cognitive operation or a difference between electroencephalography signals before and after being driven by the cognitive operation, and the feature value is a linear or non-linear feature value.

Abstract: A vision inspection and correction method, which uses an image adjustment software/device to separate the eyes of the inspected person on an independent display screen, and the visual mark seen by the same vision is designed to be misaligned; through the guidance and interaction of the inspector and the inspected person, the inspector can adjust the image operation to zoom in or out, shift, focus, diverge, and rotate, etc., so that the inspected person's binocular images can be clearly distinguished and adjusted. Then, the binocular images are aligned, and the inspector will implant the correction parameters during the image adjustment process into 3D projectors, VR (virtual reality), AR (augmented reality device), MR hybrid reality device and other equipment to adjust the binocular digital image parameters, so users have, or can provide to a lens maker, personalized adjustment for comfortable images of both eyes.

Abstract: A vision inspection and correction method, which mainly uses an image adjustment software/device to separate the eyes of the inspected person on an independent display screen, and the visual mark seen by the same vision is designed to be misaligned; through the guidance and interaction of the inspector and the inspected person, the inspector can adjust the image operation to zoom in/out/shift/focus/diverge/rotate, etc., so that the inspected person's binocular images can be clearly distinguished and adjusted.

Abstract: A system for determining a colonoscopy image is disclosed. The system includes a bowel preparation evaluation unit, an image processing unit electrically or communicatively connected to the bowel evaluation unit, and a convolutional neural network unit electrically or communicatively connected to the image processing unit. The bowel preparation evaluation unit determines whether a bowel in the colonoscopy image is clean. The image processing unit receives the colonoscopy image determined to have a clean bowel and outputted by the bowel preparation evaluation unit, and performs an image process on the colonoscopy image with clean bowel to adjust a contrast thereof. The convolutional neural network unit comprises a convolutional neural network and in a working mode, receives and determines whether the processed colonoscopy image is a cecal image, a non-cecal image, or an indeterminable colonoscopy image.

Abstract: A system for determining a colonoscopy image is disclosed. The system includes a bowel preparation evaluation unit, an image processing unit electrically or communicatively connected to the bowel evaluation unit, and a convolutional neural network unit electrically or communicatively connected to the image processing unit. The bowel preparation evaluation unit determines whether a bowel in the colonoscopy image is clean. The image processing unit receives the colonoscopy image determined to have a clean bowel and outputted by the bowel preparation evaluation unit, and performs an image process on the colonoscopy image with clean bowel to adjust a contrast thereof. The convolutional neural network unit comprises a convolutional neural network and in a working mode, receives and determines whether the processed colonoscopy image is a cecal image, a non-cecal image, or an indeterminable colonoscopy image.

Abstract: The present invention discloses a pen having a swinging decoration. A top end of the pen is installed with an animal-shaped decoration. A mandible and a tail section of the decoration are movable. When a user writes with the pen with a small applied force or the pen is in a standstill state, the mandible and the tail section are at an upper location. When the user writes with the pen with a large applied force, a refill will push an activity rod upward and compress a spring, allowing a tooth row at an upper and lower end of the activity rod to drive a left and right conjugate gear and a gear on the decoration to rotate at a same time, which further enables the mandible and the tail section to swing downward simultaneously.

Abstract: The present invention discloses a pen having a swinging decoration. A top end of the pen is installed with an animal-shaped decoration. A mandible and a tail section of the decoration are movable. When a user writes with the pen with a small applied force or the pen is in a standstill state, the mandible and the tail section are at an upper location. When the user writes with the pen with a large applied force, a refill will push an activity rod upward and compress a spring, allowing a tooth row at an upper and lower end of the activity rod to drive a left and right conjugate gear and a gear on the decoration to rotate at a same time, which further enables the mandible and the tail section to swing downward simultaneously.

Abstract: Disclosed is a net knitting method. The knitting method comprises: leading multiple first thread materials (3a) and second thread materials (3b) through first rotating members (13a?, 13b?, 13c?) and second rotating members (13a?, 13b?, 13c?) respectively, and cyclically and repeatedly performing the foregoing process through a step of rotating the first rotating members and the second rotating members simultaneously for an odd number of half circles and a step of staggering a first base (11?) and a second base (11?), so as to form an obliquely knitted net. The knitting method can improve the structural strength of the net.

Abstract: A comparator to provide an output voltage indicative of comparing an input voltage with a reference voltage, where the comparator has an asymmetric frequency response. With an asymmetric frequency response, the bandwidth of the input voltage may be greater than the bandwidth of the reference voltage. A comparator includes a differential pair of transistors coupled to a current mirror and biased by a current source, where in one embodiment, a capacitor shunts the sources of the differential pair. In a second embodiment, a capacitor couples the input voltage port to the gates of the current mirror transistors. In a third embodiment, the comparator utilizes both capacitors of the first and second embodiments.

Abstract: A shakable lighting element includes a main unit, an inner seat, a conductive rod, a spring, a swing block, an LED and an outer shade. The inner seat is latched into the main unit and is installed with the spring and the LED. The spring is connected with the swing block, an end of the conductive rod penetrates the inner seat to be in contact with a battery and the other end is transfixed in the spring. When the main unit shakes, the swing block drives the spring to swing and when the spring touches the conductive rod, the LED illuminates.

Abstract: A shakable lighting element includes a main unit, an inner seat, a conductive rod, a spring, a swing block, an LED and an outer shade. The inner seat is latched into the main unit and is installed with the spring and the LED. The spring is connected with the swing block, an end of the conductive rod penetrates the inner seat to be in contact with a battery and the other end is transfixed in the spring. When the main unit shakes, the swing block drives the spring to swing and when the spring touches the conductive rod, the LED illuminates.

Abstract: Some embodiments provide techniques for determining a set of Abbe's kernels which model an optical system of a photolithography process. During operation, the system can receive optical parameters (e.g., numerical aperture, wavelength, etc.) for the photolithography process's optical system. Next, the system can use the optical parameters to determine a point spread function for an Abbe's source. Note that the point spread function for the Abbe's source can be determined either by discretizing the optical system's light source using a set of concentric circles, or by discretizing the optical system's light source in an orthogonal fashion. The system can then determine a correlation matrix from the point spread function. Next, the system can determine the set of Abbe's kernels by performing an eigen decomposition of the correlation matrix using principal component analysis. The system can then use the set of Abbe's kernels to compute image intensity.

Abstract: A net structure includes a plurality of metal rightwards inclined wires including, in sequence, a first rightwards inclined wire, a second rightwards inclined wire, and an N-th rightwards inclined wire. The net structure further includes a plurality of metal leftwards inclined wires including, in sequence, a first leftwards inclined wire, a second leftwards inclined wire, and an N-th leftwards inclined wire. The first rightwards inclined wires intersects, in sequence, from the first rightwards inclined wire through the N-th rightwards inclined wire at an intersection at which a twine portion is formed. The second rightwards inclined wires intersects, in sequence, from the second rightwards inclined wire through the N-th rightwards inclined wire at an intersection at which a twine portion is formed. The N-th leftwards inclined wire intersects the N-th rightwards inclined wire at an intersection at which a twine portion is formed, thereby forming a net structure with a plurality of hexagonal meshes.

Abstract: A pen having a decoration includes a decoration on a penholder. The decoration contains an illuminator. When the decoration rotates, the illuminator emits light. On the other hand, upon writing with the pen, the illuminator emits the light as well. Therefore, the illuminator will emit the light by this dual switch.

Abstract: A comparator to provide an output voltage indicative of comparing an input voltage with a reference voltage, where the comparator has an asymmetric frequency response. With an asymmetric frequency response, the bandwidth of the input voltage may be greater than the bandwidth of the reference voltage. A comparator includes a differential pair of transistors coupled to a current mirror and biased by a current source, where in one embodiment, a capacitor shunts the sources of the differential pair. In a second embodiment, a capacitor couples the input voltage port to the gates of the current mirror transistors. In a third embodiment, the comparator utilizes both capacitors of the first and second embodiments.

Abstract: A pen having a decoration includes a decoration on a penholder. The decoration contains an illuminator. When the decoration rotates, the illuminator emits light. On the other hand, upon writing with the pen, the illuminator emits the light as well. Therefore, the illuminator will emit the light by this dual switch.

Abstract: A net structure includes a plurality of metal rightwards inclined wires including, in sequence, a first rightwards inclined wire, a second rightwards inclined wire, and an N-th rightwards inclined wire. The net structure further includes a plurality of metal leftwards inclined wires including, in sequence, a first leftwards inclined wire, a second leftwards inclined wire, and an N-th leftwards inclined wire. The first rightwards inclined wires intersects, in sequence, from the first rightwards inclined wire through the N-th rightwards inclined wire at an intersection at which a twine portion is formed. The second rightwards inclined wires intersects, in sequence, from the second rightwards inclined wire through the N-th rightwards inclined wire at an intersection at which a twine portion is formed. The N-th leftwards inclined wire intersects the N-th rightwards inclined wire at an intersection at which a twine portion is formed, thereby forming a net structure with a plurality of hexagonal meshes.

Abstract: Some embodiments provide techniques for determining a set of Abbe's kernels which model an optical system of a photolithography process. During operation, the system can receive optical parameters (e.g., numerical aperture, wavelength, etc.) for the photolithography process's optical system. Next, the system can use the optical parameters to determine a point spread function for an Abbe's source. Note that the point spread function for the Abbe's source can be determined either by discretizing the optical system's light source using a set of concentric circles, or by discretizing the optical system's light source in an orthogonal fashion. The system can then determine a correlation matrix from the point spread function. Next, the system can determine the set of Abbe's kernels by performing an eigen decomposition of the correlation matrix using principal component analysis. The system can then use the set of Abbe's kernels to compute image intensity.