Abstract: The present disclosure relates to novel compounds, methods, and cell-targeting formulations, e.g., a lipid nanoparticle (LNP) for targeted delivery to a tissue or a cell type. The compound and formulation provided herein are designed to have a targeting moiety configured to provide selective delivery features for the formulation and a lipid tail for being incorporated into the bilayer membrane of the formed lipid nanoparticle.

Abstract: The present disclosure provides novel compounds, methods, and cell targeting mRNA vaccine formulations for targeted delivery, such as delivery to dendritic cells. The compound and formulation provided herein are designed to have a targeting moiety configured to provide selective delivery features specific for dendritic cells and a lipid tail for incorporated into the bilayer membrane of the formed lipid nanoparticle.

Abstract: The present invention discloses a set of devices in cascade for driving display devices. For each of the driving devices, the serial-data-in pin and the serial-data-out pin traditionally used to transfer image data can further deliver commands from and/or internal statuses of the driving devices to an external controller. Accordingly, inventive functions of command transfer and/or status feedback can be achieved without adding extra pins. The present invention also discloses a device suitable for forming the driving set, in which a command register and/or a status register is provided.

Abstract: The present invention discloses a set of devices in cascade for driving display devices. For each of the driving devices, the serial-data-in pin and the serial-data-out pin traditionally used to transfer image data can further deliver commands from and/or internal statuses of the driving devices to an external controller. Accordingly, inventive functions of command transfer and/or status feedback can be achieved without adding extra pins. The present invention also discloses a device suitable for forming the driving set, in which a command register and/or a status register is provided.