Patents by Inventor Chung-Yuan Hsu

Chung-Yuan Hsu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250047018
    Abstract: A conductive terminal is suitable for being installed in a terminal receiving slot of a base, and includes a main body, an elastic arm portion and a foot connecting portion. The main body includes a holding portion and a buckle portion. The elastic arm portion includes a reversed folded portion, an abutment portion, a bending portion and a conductive portion. The reversed folded portion extends downward from a lower surface of the main body and extends upward after being folded. The abutment portion is opposite to the main body, and located between the reversed folded portion and the bending portion. The bending portion is connected to the abutment portion and the conductive portion. The foot connecting portion is connected to the main body or the reversed folded portion, and provided with a ball soldering member for connecting to soldering balls.
    Type: Application
    Filed: March 26, 2024
    Publication date: February 6, 2025
    Inventors: Shan-Yong CHENG, Chang-Chi YEH, Chung-Yuan HSU
  • Patent number: 12054561
    Abstract: The present invention provides a bi-functional fusion protein, (AT)a-Fc-(VT)b, simultaneously targeting vascular endothelial growth factor (VEGF) and angiopoietins (ANGs), wherein AT is an ANG binding motif; and VT is a VEGF binding motif, Fragment crystallizable region (Fc) is an N-terminal of Immunoglobulin G (IgG); each of a and b is an integer from 1 to 10. The bi-functional fusion proteins contain two or more domains of human proteins and are of all human sequences, and thus are expected to be non-immunogenic, and potentially can be used therapeutically in human targeting angiogenesis-associated diseases.
    Type: Grant
    Filed: December 14, 2021
    Date of Patent: August 6, 2024
    Assignee: TRICAN BIOTECHNOLOGY CO., LTD
    Inventors: Huang-Tsu Chen, Jiun-Shyang Leou, Chung-Yuan Hsu, Cheng-Ke Li, Yun-Ting Wang, Li-Tsen Lin
  • Patent number: 11986285
    Abstract: A disease diagnosing method and a disease diagnosing system are provided in the disclosure. The disease diagnosing method includes: obtaining continuous images of a body skin and generating a time domain signal according to an average pixel value of a region of interest in each frame of the continuous images; transforming the time domain signal to a frequency domain signal and combining the time domain signal and the frequency domain signal to a time frequency signal; retrieving multiple first features of a first high dimensional space of the time frequency signal to obtain multiple second features of a second high dimensional space; and use the second features as feature vectors to map to a high dimension feature space, and classifying the second features as one of the multiple categories of a disease corresponding to the region of interest in the body skin according to a hyperplane of the high dimension feature space.
    Type: Grant
    Filed: October 25, 2021
    Date of Patent: May 21, 2024
    Assignee: National Taiwan University
    Inventors: Hao-Ming Hsiao, Hsien-Li Kao, Mao-Shin Lin, Chung-Yuan Hsu
  • Patent number: 11518819
    Abstract: The present invention provides a bi-functional fusion protein, (AT)a-Fc-(VT)b, simultaneously targeting vascular endothelial growth factor (VEGF) and angiopoietins (ANGs), wherein AT is an ANG binding motif; and VT is a VEGF binding motif, Fragment crystallizable region (Fc) is an N-terminal of Immunoglobulin G (IgG); each of a and b is an integer from 1 to 10. The bi-functional fusion proteins contain two or more domains of human proteins and are of all human sequences, and thus are expected to be non-immunogenic, and potentially can be used therapeutically in human targeting angiogenesis-associated diseases.
    Type: Grant
    Filed: August 19, 2019
    Date of Patent: December 6, 2022
    Assignee: TRICAN BIOTECHNOLOGY CO., LTD
    Inventors: Huang-Tsu Chen, Jiun-Shyang Leou, Chung-Yuan Hsu, Cheng-Ke Li, Yun-Ting Wang, Li-Tsen Lin
  • Patent number: 11390677
    Abstract: The present invention provides antibodies that bind to CD47 with high affinity and specificity, and their use in treatment of a cancer.
    Type: Grant
    Filed: July 3, 2019
    Date of Patent: July 19, 2022
    Assignee: TRICAN BIOTECHNOLOGY CO., LTD.
    Inventors: Huang-Tsu Chen, Jiun-Shyang Leou, Chung-Yuan Hsu, Cheng-Ke Li, Yun-Ting Wang, Li-Tsen Lin, Shiou-Ting Chen, Chen-Wei Chiang
  • Publication number: 20220169750
    Abstract: The present invention provides a bi-functional fusion protein, (AT)a-Fc-(VT)b, simultaneously targeting vascular endothelial growth factor (VEGF) and angiopoietins (ANGs), wherein AT is an ANG binding motif; and VT is a VEGF binding motif, Fragment crystallizable region (Fc) is an N-terminal of Immunoglobulin G (IgG); each of a and b is an integer from 1 to 10. The bi-functional fusion proteins contain two or more domains of human proteins and are of all human sequences, and thus are expected to be non-immunogenic, and potentially can be used therapeutically in human targeting angiogenesis-associated diseases.
    Type: Application
    Filed: December 14, 2021
    Publication date: June 2, 2022
    Applicant: TRICAN BIOTECHNOLOGY CO., LTD
    Inventors: Huang-Tsu CHEN, Jiun-Shyang LEOU, Chung-Yuan HSU, Cheng-Ke LI, Yun-Ting WANG, Li-Tsen LIN
  • Publication number: 20220133171
    Abstract: A disease diagnosing method and a disease diagnosing system are provided in the disclosure. The disease diagnosing method includes: obtaining continuous images of a body skin and generating a time domain signal according to an average pixel value of a region of interest in each frame of the continuous images; transforming the time domain signal to a frequency domain signal and combining the time domain signal and the frequency domain signal to a time frequency signal; retrieving multiple first features of a first high dimensional space of the time frequency signal to obtain multiple second features of a second high dimensional space; and use the second features as feature vectors to map to a high dimension feature space, and classifying the second features as one of the multiple categories of a disease corresponding to the region of interest in the body skin according to a hyperplane of the high dimension feature space.
    Type: Application
    Filed: October 25, 2021
    Publication date: May 5, 2022
    Applicant: National Taiwan University
    Inventors: Hao-Ming Hsiao, Hsien-Li Kao, Mao-Shin Lin, Chung-Yuan Hsu
  • Publication number: 20200115443
    Abstract: The present invention provides a bi-functional fusion protein simultaneously targeting the complement and the vascular endothelial growth factor (VEGF). The bi-functional fusion proteins contain two or more domains of human proteins and are of all human sequences, and thus are expected to be non-immunogenic, and potentially can be used therapeutically in human targeting complement and VEGF related diseases.
    Type: Application
    Filed: October 11, 2019
    Publication date: April 16, 2020
    Applicant: Trican Biotechnology Co., Ltd
    Inventors: Huang-Tsu Chen, Jiun-Shyang Leou, Chung-Yuan Hsu, Cheng-Ke Li, Yun-Ting Wang, Li-Tsen Lin
  • Publication number: 20200055958
    Abstract: The present invention provides a bi-functional fusion protein, (AT)a-Fc-(VT)b, simultaneously targeting vascular endothelial growth factor (VEGF) and angiopoietins (ANGs), wherein AT is an ANG binding motif; and VT is a VEGF binding motif, Fc is an N-terminal of IgG; each of a and b is an integer from 1 to 10. The bi-functional fusion proteins contain two or more domains of human proteins and are of all human sequences, and thus are expected to be non-immunogenic, and potentially can be used therapeutically in human targeting angiogenesis-associated diseases.
    Type: Application
    Filed: August 19, 2019
    Publication date: February 20, 2020
    Applicant: TRICAN BIOTECHNOLOGY CO., LTD
    Inventors: Huang-Tsu CHEN, Jiun-Shyang LEOU, Chung-Yuan HSU, Cheng-Ke LI, Yun-Ting WANG, Li-Tsen LIN
  • Publication number: 20160156559
    Abstract: A load balancing method for searching a key of a search peer in a structured peer-to-peer network. The structured peer-to-peer network has indexes of a key shared sequentially among peers in different zones, each peer sharing the key having a same modulo identity and a counter value. The loading balancing method includes hashing a keyword to get the key, wherein the keyword is obtained from a query of the search peer, finding a target peer based on the key, obtaining the counter value from the target peer, wherein the counter value indicates number of zones that have shared the indexes of the same key, determining the shared peers in the zones according to the counter value and the modulo identity, sending a search message to the peers, and receiving answers from the shared peers. The action of finding the target peer is implemented using a lookup procedure.
    Type: Application
    Filed: February 9, 2016
    Publication date: June 2, 2016
    Inventors: Chung-Yuan HSU, Kuochen WANG, Hung-Cheng SHIH
  • Patent number: 9294561
    Abstract: An approach is provided for reassigning and sharing loads to peers with a same identity, which is based on a threshold. The peers are configured to store indexes of a key and to share the same loading (i.e., indexes) of the key to the peers with same secondary identities in different zones. The secondary identity is derived and has a modulo relationship with a first identity of the peer. The threshold indicates maximum number of indexes stored in each peer. Therefore, the loading are distributed evenly to peers in different zones, which achieves load balance to a decentralized structured peer-to-peer network.
    Type: Grant
    Filed: May 10, 2013
    Date of Patent: March 22, 2016
    Assignee: NATIONAL CHIAO TUNG UNIVERSITY
    Inventors: Chung-Yuan Hsu, Kuochen Wang, Hung-Cheng Shih
  • Publication number: 20130275599
    Abstract: An approach is provided for reassigning and sharing loads to peers with a same identity, which is based on a threshold. The peers are configured to store indexes of a key and to share the same loading (i.e., indexes) of the key to the peers with same secondary identities in different zones. The secondary identity is derived and has a modulo relationship with a first identity of the peer. The threshold indicates maximum number of indexes stored in each peer. Therefore, the loading are distributed evenly to peers in different zones, which achieves load balance to a decentralized structured peer-to-peer network.
    Type: Application
    Filed: May 10, 2013
    Publication date: October 17, 2013
    Inventors: Chung-Yuan HSU, Kuochen WANG, Hung-Cheng SHIH
  • Patent number: 8443086
    Abstract: An approach is provided for reassigning and sharing loads to peers with a same identity, which is based on a threshold. The peers are configured to store indexes of a key and to share the same loading (i.e., indexes) of the key to the peers with same secondary identities in different zones. The secondary identity is derived and has a modulo relationship with a first identity of the peer. The threshold indicates maximum number of indexes stored in each peer. Therefore, the loading are distributed evenly to peers in different zones, which achieves load balance to a decentralized structured peer-to-peer network.
    Type: Grant
    Filed: June 22, 2011
    Date of Patent: May 14, 2013
    Assignee: National Chiao Tung University
    Inventors: Chung-Yuan Hsu, Kuochen Wang, Hung-Cheng Shih
  • Publication number: 20120331146
    Abstract: An approach is provided for reassigning and sharing loads to peers with a same identity, which is based on a threshold. The peers are configured to store indexes of a key and to share the same loading (i.e., indexes) of the key to the peers with same secondary identities in different zones. The secondary identity is derived and has a modulo relationship with a first identity of the peer. The threshold indicates maximum number of indexes stored in each peer. Therefore, the loading are distributed evenly to peers in different zones, which achieves load balance to a decentralized structured peer-to-peer network.
    Type: Application
    Filed: June 22, 2011
    Publication date: December 27, 2012
    Inventors: Chung-Yuan Hsu, Kuochen Wang, Hung-Cheng Shih
  • Patent number: D397459
    Type: Grant
    Filed: April 28, 1997
    Date of Patent: August 25, 1998
    Assignee: American Candle Designs, Inc.
    Inventor: John Chung-Yuan Hsu