Abstract: Disclosed is a method of preparing glufosinate, and specifically a method of preparing glufosinate represented by formula (1) or its salt or enantiomer, or a mixture of its enantiomers in any ratio, comprising a step of hydrolyzing a compound of formula (III) to generate a compound of formula (1). Due to a distinctive reaction mechanism adopted in the method of the present disclosure, a halogenated hydrocarbon by-product in the Michaelis-Arbuzov reaction can be avoided and thus the destructive impact of the halogenated hydrocarbon by-product on ozone in the aerosphere can be prevented. Accordingly, the equipment and engineering investments required for the separation, purification, and collection of the foregoing by-product are eliminated, and the potential environmental and safety hazards brought by the foregoing by-product are also avoided.

Abstract: In some embodiments, a method can include: receiving, by a computing device, a plurality of messages, where at least a first one of the plurality of messages is associated with a first application and at least a second one of the plurality of messages is associated with a second application different from the first; receiving, by the computing device, information about one or more scheduled meetings; determining, by the computing device, one or more of the plurality of messages that are associated with a first meeting of the one or more scheduled meetings; and sending, by the computing device, information about the associations of the one or more of the plurality of messages and the first meeting to another computing device to enable the another computing device to display a list of the one or more of the plurality of messages in conjunction with the first meeting.

Abstract: In some embodiments, a method can include: receiving, by a computing device, a plurality of messages, where at least a first one of the plurality of messages is associated with a first application and at least a second one of the plurality of messages is associated with a second application different from the first; receiving, by the computing device, information about one or more scheduled meetings; determining, by the computing device, one or more of the plurality of messages that are associated with a first meeting of the one or more scheduled meetings; and sending, by the computing device, information about the associations of the one or more of the plurality of messages and the first meeting to another computing device to enable the another computing device to display a list of the one or more of the plurality of messages in conjunction with the first meeting.

Abstract: According to some embodiments of the disclosure, a method includes: receiving, at a computing device, content of an online meeting; analyzing, by the computing device, the content to identify one or more topics communicated by one or more client devices participating in the online meeting; associating, by the computing device, ones of the one or more topics to one or more text segments of the content; and providing, by the computing device, annotations for the online meeting to at least one of the one or more client devices participating in the online meeting, the annotations representative of the one or more topics and the associated text segments.

Abstract: The present invention provides a tetrahydroprotoberberine compound represented by the formula (I), enantiomers, diastereomers, racemates and mixtures thereof, and pharmaceutically acceptable salts, crystalline hydrates and solvates thereof. The invention also provides a method for preparing the compound and the use thereof in the preparation of a medicament for preventing and/or treating central nervous system diseases.

Abstract: One disclosed method involves a computing system determining a keyword of interest for an online meeting being presented via a user interface, determining that content of the online meeting corresponds to the keyword of interest, and causing, in response to the content of the online meeting corresponding to the keyword of interest, the user interface to output an indication that the content of the online meeting being presented is potentially of interest. Another disclosed method involves a computing system determining data indicative of a number of client devices, from a plurality of client devices participating in an online meeting, for which a user interface for the online meeting is presented in an active window, and causing, based at least in part on the data, a first client device, from the plurality of client devices, to output an indication that content of the online meeting being presented is potentially of interest.

Abstract: A computing system may determine that first data received from a first system of record is indicative of a first event of the first system of record, and send a first notification indicative of the first event to a client device operated by a first user. The computing system may further determine that second data received from a second system of record is indicative of a second event for which the first user is to provide a response to the second system of record, send a second notification indicative of the second event to the client device, determine that the first user has not provided the response to the second system of record, and based at least in part on the first user not having provided the response to the second system of record, send a third notification indicative of the second event to the client device.

Abstract: The present invention relates to a fused ring compound represented by general formula (I), a stereoisomer or a pharmaceutically acceptable salt thereof, a preparation method therefor, a pharmaceutical composition and use thereof. The compound provided in the present invention is useful for treating, preventing and/or controlling various nervous system disorders. The compound provided in the present invention modulates one or more monoamine transporters, inhibits the reuptake of endogenous monoamines such as dopamine, 5-hydroxytryptamine, and norepinephrine (e.g., from the synaptic cleft), and/or modulates the 5-HT3 receptor.

Abstract: The present application discloses a display substrate. The display substrate includes a base substrate; a color filter on the base substrate; and an overcoat layer on a side of the color filter distal to the base substrate. The overcoat layer includes a first sublayer and a second sublayer, the second sublayer on a side of the first sublayer distal to the base substrate. The first sublayer includes a first polymer material. The second sublayer includes a second polymer material different from the first polymer material.

Abstract: A touch panel comprises a first substrate (1), a second substrate (2) opposite to the first substrate (1), and spacers (5) between the first substrate (1) and the second substrate (2). At least one of the spacers (5) comprises a piezoelectric material. The piezoelectric material is a graphene-polyborosiloxane composite.

Abstract: The present application discloses a display substrate. The display substrate includes a base substrate; a color filter on the base substrate; and an overcoat layer on a side of the color filter distal to the base substrate. The overcoat layer includes a first sublayer and a second sublayer, the second sublayer on a side of the first sublayer distal to the base substrate. The first sublayer includes a first polymer material. The second sublayer includes a second polymer material different from the first polymer material.

Abstract: A touch panel comprises a first substrate (1), a second substrate (2) opposite to the first substrate (1), and spacers (5) between the first substrate (1) and the second substrate (2). At least one of the spacers (5) comprises a piezoelectric material. The piezoelectric material is a graphene-polyborosiloxane composite.

Abstract: The embodiments of the present disclosure provide a base plate, a manufacturing method thereof and a display panel, relating to the field of display technology. Ink droplets in grooves defined by a pixel defining layer can be spread uniformly, thereby effectively improving the product quality and the display effect. The base plate comprises a substrate and a pixel defining layer arranged on the substrate, wherein the pixel defining layer comprises dams and several micron-sized protrusions arranged on the upper surfaces and sides of the dams; and the protrusions have lyophobic property.

Abstract: The low profile screw base comprises a screw base body and a positioning compression ring. An assembly hole penetrates longitudinally through the screw base body. A U-shaped slot for a connecting rod to pass through is provided on an upper portion of the screw base body. The inner wall of the screw base body on the opposite sides of the U-shaped slot is provided with internal threads. Snapping protrusions are formed on the inner wall of the screw base body on the opposite sides of the U-shaped slot below the internal threads. A lower ball socket matched with the round head of the ball screw is arranged in the assembly hole of the lower portion of the screw base body. The positioning compression ring used for compressing the round head is snap fitted above the lower ball socket and below the snapping protrusions (6).

Abstract: The present invention provides a tetrahydroprotoberberine compound represented by the formula (I), enantiomers, diastereomers, racemates and mixtures thereof, and pharmaceutically acceptable salts, crystalline hydrates and solvates thereof. The invention also provides a method for preparing the compound and the use thereof in the preparation of a medicament for preventing and/or treating central nervous system diseases.

Abstract: A display substrate motherboard and a manufacturing method and a detecting method thereof are provided. The display substrate motherboard includes a base substrate, a plurality of display substrate regions located on the base substrate to form a plurality of display substrates, and a plurality of spacer regions located among the display substrate regions, at least one detecting region being disposed in the spacer regions. The detecting region includes at least one film layer. The display substrate region includes at least one film layer which is disposed in a same layer as the at least one film layer of the detecting region, the film layer of the detecting region having a same thickness as the film layers in the display substrate regions.

Abstract: The embodiments of the present disclosure provide a base plate, a manufacturing method thereof and a display panel, relating to the field of display technology. Ink droplets in grooves defined by a pixel defining layer can be spread uniformly, thereby effectively improving the product quality and the display effect. The base plate comprises a substrate and a pixel defining layer arranged on the substrate, wherein the pixel defining layer comprises dams and several micron-sized protrusions arranged on the upper surfaces and sides of the dams; and the protrusions have lyophobic property.

Abstract: The present invention provides a heterocyclic compound represented by the formula (I), its stereoisomers, or a pharmaceutically acceptable salt thereof, pharmaceutical compositions thereof, and their use in preparing a medicament for the prevention and/or treatment of central nervous system disease.

Abstract: The present invention relates to the methods for preparing brexpiprazole, the analogs, key intermediates, and salts thereof, specifically, the present invention relates to a new method for preparing brexpiprazole, the analogs, key intermediates, and salts thereof, and the key intermediates, and salts thereof provided during the preparation. The preparation method has a mild reaction condition, stable intermediate, easy operation, and uses cheap and easy-to-get reagents, thus it saves the synthesis cost, shortens the production cycle, improves the yield and product quality, and is suitable for mass production.

Abstract: A uniplanar pedicle screw comprises a screw base, a positioning compression ring and a ball-head screw. Lateral bosses are provided at left and right sides of an upper portion of a ball head of the ball-head screw, and upper side surfaces of the lateral bosses are arc-shaped and project upwards. A central boss is provided on the ball head of the ball-head screw between the two lateral bosses, and an upper side surface of the central boss is arc-shaped and protrudes upwards. An arc center of the central boss and a connecting line of arc centers of the two lateral bosses are on the same straight line. Arc-shaped concave surfaces matching the two lateral bosses are provided at a lower portion of the positioning compression ring and at left and right sides of a rod accommodating groove.