Patents by Inventor Chunling Yi

Chunling Yi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • USE OF INHIBITORS OF YAP AND SOX2 FOR THE TREATMENT OF CANCER
    Publication number: 20220280590
    Abstract: Methods of inducing apoptosis and inhibiting proliferation in YAP-dependent cancer cells, involving contacting the cells with one or more inhibitors of YAP and one or more inhibitors of SOX2. In addition, methods of treating or preventing YAP-dependent cancer in subjects, involving administering to the subject one or more inhibitors of YAP and one or more inhibitors of SOX2.
    Type: Application
    Filed: August 20, 2020
    Publication date: September 8, 2022
    Applicant: Georgetown University
    Inventors: Chunling Yi, Shigekazu Murakami
  • USE OF INHIBITORS OF YAP/TAZ FOR THE TREATMENT OF CANCER
    Publication number: 20220233535
    Abstract: Methods of treating or preventing cancer, or treating or preventing noncancerous tumors or lesions, in a subject in need thereof. The methods involve administering a therapeutically effective amount of one or more inhibitors of the YAP/TAZ pathway to the subject. In addition, methods of inhibiting or preventing glycolysis in cancer cells in a subject, promoting mitochondrial respiration in cancer cells in a subject, and promoting oxidative stress in cancer cells in a subject, by administering a therapeutically effective amount of one or more inhibitors of the YAP/TAZ pathway to the subject.
    Type: Application
    Filed: April 26, 2020
    Publication date: July 28, 2022
    Inventors: Chunling Yi, Shannon M. White, Jeffrey Field