Patents by Inventor Chunna Dong

Chunna Dong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bifunctional fusion protein with thrombolytic and anticoagulant activities and uses thereof
    Patent number: 8212003
    Abstract: This application relates to a fusion protein, which is composed of a thrombolytic protein, an anticoagulant protein, and a linker peptide. In particular, the fusion protein is composed of an anticoagulant protein and a protein molecule having plasminogen-activating activity, wherein said two proteins are linked together via a linker peptide, which can be recognized and cleaved by blood coagulation factors. The application also relates to the medical use of said fusion protein, and to the use of the linker peptide which can be recognized by blood coagulation factor in linking a thrombolytic protein and an anticoagulation protein.
    Type: Grant
    Filed: September 3, 2003
    Date of Patent: July 3, 2012
    Assignee: Institute of Radiation Medicine, Academy of Military Medical Sciences, PLA
    Inventors: Bingxing Shi, Zuze Wu, Aiping Yu, Chunna Dong
  • Fused protein with the function of both hemolysis and anticoagulation and use of it
    Publication number: 20060127389
    Abstract: This application relates to a fusion protein, which is composed of a thrombolytic protein, an anticoagulant protein, and a linker peptide. In particular, the fusion protein is composed of an anticoagulant protein and a protein molecule having plasminogen-activating activity, wherein said two proteins are linked together via a linker peptide, which can be recognized and cleaved by blood coagulation factors. The application also relates to the medical use of said fusion protein, and to the use of the linker peptide which can be recognized by blood coagulation factor in linking a thrombolytic protein and an anticoagulation protein.
    Type: Application
    Filed: September 3, 2003
    Publication date: June 15, 2006
    Inventors: Bingxing Shi, Zuze Wu, Aiping Yu, Chunna Dong