Patents by Inventor Chunnian Liang

Chunnian Liang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250188418
    Abstract: The present disclosure relates to the technical field of gene engineering, and in particular, to use of miR-22-3p in promoting the differentiation of yak myoblasts. miR-22-3pmimic can significantly promote the expression of miR-22-3p, and can also significantly increase the expression of differentiation marker genes MYF5 and MYOD at the mRNA and protein levels. miR-22-3p inhibitor can significantly inhibit the expression of miR-22-3p, and can significantly promote the expression of MYF5 and MYOD at the mRNA and protein levels. miR-22-3p mimic can significantly promote the formation of myotubes, while miR-22-3p inhibitor can significantly inhibit the formation of myotubes. The above results indicate that miR-22-3p has a promoting effect in the differentiation process of myoblasts.
    Type: Application
    Filed: December 6, 2024
    Publication date: June 12, 2025
    Applicants: Lanzhou Institute of Husbandry and Pharmaceutical Sciences, Chinese Academy of Agricultural Sciences, Institute of Western Agriculture, the, Chinese Academy of Agricultural Sciences
    Inventors: Xiaoming MA, Chunnian LIANG, Ping YAN, Xian GUO, Min CHU, Yongfu LA, Pengjia BAO, Xiaoyun WU, Tong Wang, Qianyun GE
  • Publication number: 20240360440
    Abstract: The present invention provides a bos grunniens Lnc4047 and applications thereof, and belongs to the technical field of genetic engineering. The nucleotide sequence of the bos grunniens Lnc4047 is shown in SEQ ID No. 1. The regulation effect of Lnc4047 on myoblast proliferation and myoblast differentiation of bos grunniens is discovered in the present invention for the first time, that is, Lnc4047 inhibits myoblast proliferation, but promotes myoblast differentiation to a certain extent. This provides an important basis for understanding the muscle development mechanism of bos grunniens, and lays a theoretical foundation for rapidly developing a new high-quality breed of bos grunniens and improving its meat quality.
    Type: Application
    Filed: April 27, 2023
    Publication date: October 31, 2024
    Inventors: Xiaoming Ma, Ping Yan, Chunnian Liang, Xian Guo, Tong Wang