Abstract: Described herein are novel trinucleotide cap analogs and methods of making and using the same. Also described herein is an RNA molecule comprising a 5?-cap, wherein the 5?-cap includes a trinucleotide cap analog as described herein. Methods of inducing a therapeutic effect in a 5 subject are also described herein, the methods including a step of administering to the subject an RNA molecule including the trinucleotide cap analog.

Abstract: Described herein are compounds and compositions for treating drug resistant and persistent tuberculosis. Also described herein is a method of screening for identifying biofilm formation inhibitors.

Abstract: Involved is a method for controlling the pest Sesamia inferens, comprising a step of contacting Sesamia inferens with Cry1F protein. Sesamia inferens is controlled by the Cry1F protein having pesticidal activity against Sesamia inferens, which is produced in the plants. Compared with the agricultural control, chemical control and biology control currently used in prior art, the present invention can protect the whole plant during whole growth period from the harm of Sesamia inferen. Furthermore, it causes no pollution and no residue and provides a stable and thorough control effect. Also it is simple, convenient and economic.