Patents by Inventor Chunqi LI

Chunqi LI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Five-membered heterocyclic amides WNT pathway inhibitor
    Patent number: 10821104
    Abstract: A five-membered heterocyclic amide WNT pathway inhibitor having the following general structural formula: The five-membered heterocyclic amide WNT pathway inhibitor has a remarkable anti-tumor activity based on a target-based rational drug design, and can be used for the development of a new generation of Wnt pathway inhibitors, and has a great clinical application value and considerable market potential.
    Type: Grant
    Filed: December 7, 2016
    Date of Patent: November 3, 2020
    Assignee: Suzhou Sinovent Pharmaceuticals Co., Ltd.
    Inventors: Yonghui Wang, Yan Zhu, Juan Zhou, Yujun Gao, Shiqun Wang, Dong Wang, Wandeng Liu, Ximing Shen, Binbin Hong, Tao Liu, Yaodong Wu, Chunqi Li
  • Benzofuran pyrazole amine kinase inhibitor
    Patent number: 10710993
    Abstract: The present invention discloses a compound for regulating protein kinase activity and used for treating or preventing diseases associated with protein kinases. Specifically, the present invention relates to a benzofuran pyrazole amine protein kinase inhibitor which belongs to compounds that regulate anaplastic lymphoma kinase (ALK), and provides a method of preparing such a compound and a pharmaceutical use of such a compound in the treatment or prevention of diseases associated with ALK. The inhibitor can solve the problem of the drug resistance of the first generation and the second generation of ALK inhibitors.
    Type: Grant
    Filed: June 27, 2017
    Date of Patent: July 14, 2020
    Assignee: HANGZHOU REX PHARMACEUTICAL CO., LTD.
    Inventors: Yonghui Wang, Juan Zhou, Yujun Gao, Dong Wang, Binbin Hong, Ximing Shen, Yaodong Wu, Chunqi Li
  • BENZOFURAN PYRAZOLE AMINE KINASE INHIBITOR
    Publication number: 20190225600
    Abstract: The present invention discloses a compound for regulating protein kinase activity and used for treating or preventing diseases associated with protein kinases. Specifically, the present invention relates to a benzofuran pyrazole amine protein kinase inhibitor which belongs to compounds that regulate anaplastic lymphoma kinase (ALK), and provides a method of preparing such a compound and a pharmaceutical use of such a compound in the treatment or prevention of diseases associated with ALK. The inhibitor can solve the problem of the drug resistance of the first generation and the second generation of ALK inhibitors.
    Type: Application
    Filed: June 27, 2017
    Publication date: July 25, 2019
    Inventors: Yonghui WANG, Juan ZHOU, Yujun GAO, Dong WANG, Binbin HONG, Ximing SHEN, Yaodong WU, Chunqi LI
  • FIVE-MEMBERED HETEROCYCLIC AMIDES WNT PATHWAY INHIBITOR
    Publication number: 20180271846
    Abstract: The present invention discloses a five-membered heterocyclic amide WNT pathway inhibitor, which belongs to a compound that regulates the activity of a Wnt signaling pathway, and provides a method for preparing such a compound, and the use of such a compound in preparing a medicament that antagonizes the Wnt signaling pathway. The five-membered heterocyclic amide WNT pathway inhibitor provided by the invention has a remarkable anti-tumor activity based on a target-based rational drug design of, and can be used for the development of a new generation of Wnt pathway inhibitors, and has a great clinical application value and considerable market potential.
    Type: Application
    Filed: December 7, 2016
    Publication date: September 27, 2018
    Inventors: Yonghui WANG, Yan ZHU, Juan ZHOU, Yujun GAO, Shiqun WANG, Dong WANG, Wandeng LIU, Ximing SHEN, Binbin HONG, Tao LIU, Yaodong WU, Chunqi LI