Patents by Inventor Chunquan SHENG

Chunquan SHENG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Mercaptonicotinic acid compound and preparation method and use thereof
    Patent number: 10035771
    Abstract: The present invention discloses a class of mercaptonicotinic acid compound and preparation method and use thereof; the general structural formula of the compound is as shown in Formula I. Experiment demonstrates that the mercaptonicotinic acid compound could inhibit activity of botulinum toxin endopeptidase and tetanus toxin endopeptidase in vitro, which has a significant protective effect on botulinum toxin poisoning in mice, and can be used for preparing medicine intended to prevent and/or treat botulism, as well as to prevent botulinum toxin exposure and tetanus.
    Type: Grant
    Filed: May 19, 2014
    Date of Patent: July 31, 2018
    Assignee: INSTITUTE OF MICROBIOLOGY AND EPIDEMIOLOGY, ACADEMY OF MILITARY MEDICAL SCIENCES, PR CHINA
    Inventors: Hui Wang, Wannian Zhng, Zhenyuan Miao, Tao Li, Xiong Liu, Yuelin Wu, Sen Luo, Chunquan Sheng, Xiaoxue Lu, Jianzhong Yao
  • MERCAPTONICOTINIC ACID COMPOUND AND PREPARATION METHOD AND USE THEREOF
    Publication number: 20160083347
    Abstract: The present invention discloses a class of mercaptonicotinic acid compound and preparation method and use thereof; the general structural formula of the compound is as shown in Formula I. Experiment demonstrates that the mercaptonicotinic acid compound could inhibit activity of botulinum toxin endopeptidase and tetanus toxin endopeptidase in vitro, which has a significant protective effect on botulinum toxin poisoning in mice, and can be used for preparing medicine intended to prevent and/or treat botulism, as well as to prevent botulinum toxin exposure and tetanus.
    Type: Application
    Filed: May 19, 2014
    Publication date: March 24, 2016
    Applicants: INSTITUTE OF MICROBIOLOGY AND EPIDEMIOLOGY, ACADEMY OF MILITARY MEDICAL SCIENCES, PR CHINA, THE SECOND MILITARY MEDICAL UNIVERSITY
    Inventors: Hui WANG, Wannian ZHNG, Zhenyuan MIAO, Tao LI, Xiong LIU, Yuelin WU, Sen LUO, Chunquan SHENG, Xiaoxue LU, Jianzhong YAO