Patents by Inventor Chunxiao FU

Chunxiao FU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TARGETED MEASURE OF TRANSCRIPTIONAL ACTIVITY RELATED TO HORMONE RECEPTORS
    Publication number: 20220403474
    Abstract: Provided herein are methods of determining tumoral sensitivity to hormonal (endocrine) therapy based upon an index of estrogen receptor (ER)- and progesterone receptor (PR)-related genes, referred to as the sensitivity to endocrine therapy index (SETER/PR index), and may have additional consideration for the proportion of ER gene (ESR1) RNA transcripts that contain a mutation relative to the value of the SETER/PR index. Further provided are methods of treating breast cancer patients determined to be sensitive to an endocrine therapy by the SETER/PR index.
    Type: Application
    Filed: August 25, 2022
    Publication date: December 22, 2022
    Applicants: Board of Regents, The University of Texas System, Yale University
    Inventors: William Fraser SYMMANS, Bruno SINN, Christos HATZIS, Chunxiao FU, Rosanna LAU
  • Targeted measure of transcriptional activity related to hormone receptors
    Patent number: 11459617
    Abstract: Provided herein are methods of determining tumoral sensitivity to hormonal (endocrine) therapy based upon an index of estrogen receptor (ER)- and progesterone receptor (PR)-related genes, referred to as the sensitivity to endocrine therapy index (SETER/PR index), and may have additional consideration for the proportion of ER gene (ESRI) RNA transcripts that contain a mutation relative to the value of the SETER/PR index. Further provided are methods of treating breast cancer patients determined to be sensitive to an endocrine therapy by the SETER/PR index.
    Type: Grant
    Filed: April 28, 2017
    Date of Patent: October 4, 2022
    Assignees: Board of Regents, The University of Texas System, Yale University
    Inventors: William Fraser Symmans, Bruno Sinn, Christos Hatzis, Chunxiao Fu, Rosanna Lau
  • TARGETED MEASURE OF TRANSCRIPTIONAL ACTIVITY RELATED TO HORMONE RECEPTORS
    Publication number: 20210292842
    Abstract: Provided herein are methods of determining tumoral sensitivity to hormonal (endocrine) therapy based upon an index of estrogen receptor (ER)- and progesterone receptor (PR)-related genes, referred to as the sensitivity to endocrine therapy index (SETER/PR index), and may have additional consideration for the proportion of ER gene (ESRI) RNA transcripts that contain a mutation relative to the value of the SETER/PR index. Further provided are methods of treating breast cancer patients determined to be sensitive to an endocrine therapy by the SETER/PR index.
    Type: Application
    Filed: April 28, 2017
    Publication date: September 23, 2021
    Applicants: Board of Regents, The University of Texas System, Yale University
    Inventors: William Fraser SYMMANS, Bruno SINN, Christos HATZIS, Chunxiao FU, Rosanna LAU