Patents by Inventor Chunxiao YU

Chunxiao YU has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NOVEL CYTOKINE PRODRUGS
    Publication number: 20250127858
    Abstract: Provided herein are cytokine muteins and cytokine prodrugs and methods of making and using thereof.
    Type: Application
    Filed: November 26, 2024
    Publication date: April 24, 2025
    Applicant: ASKGENE PHARMA, INC.
    Inventors: Chunxiao YU, Yuefeng LU, Jian-Feng LU
  • CHIMERIC MOLECULES COMPRISING IL-12 AGONIST POLYPEPTIDE
    Publication number: 20250051413
    Abstract: The present application relates to novel chimeric molecules or prodrugs of IL-12. Specifically, disclosed provides a chimeric molecule, which comprises an IL-12 p40 subunit (p40), an IL-12 p35 subunit (p35), and which may further comprises a masking moiety (MM), and/or a carrier (C). Further included in the present application are methods of making and using the novel chimeric molecules or prodrugs.
    Type: Application
    Filed: January 12, 2022
    Publication date: February 13, 2025
    Applicant: AskGene Pharma Inc.
    Inventors: Yuefeng Lu, Chunxiao Yu, Liqin Liu
  • NOVEL IL-15 PRODRUGS AND METHODS OF USE THEREOF
    Publication number: 20240067739
    Abstract: Provided herein are IL-15 cytokine prodrugs and methods of making and using thereof.
    Type: Application
    Filed: October 19, 2023
    Publication date: February 29, 2024
    Applicant: ASKGENE PHARMA, INC.
    Inventors: Yuefeng LU, Chunxiao YU, Jian-Feng LU
  • IL-15 prodrugs and methods of use thereof
    Patent number: 11845801
    Abstract: Provided herein are IL-15 cytokine prodrugs and methods of making and using thereof.
    Type: Grant
    Filed: June 12, 2020
    Date of Patent: December 19, 2023
    Assignee: ASKGENE PHARMA, INC.
    Inventors: Yuefeng Lu, Chunxiao Yu, Jian-Feng Lu
  • NOVEL MASKED CYTOKINES AND METHODS OF USE THEREOF
    Publication number: 20230108562
    Abstract: Provided herein are prodrugs and methods of making and using thereof for stimulating the immune system, or treating cancer, autoimmune or an infectious disease.
    Type: Application
    Filed: January 11, 2021
    Publication date: April 6, 2023
    Applicant: ASKGENE PHARMA, INC.
    Inventors: Yuefeng LU, Chunxiao YU, Jian-Feng LU, Liqin LIU
  • CYTOKINE PRODRUGS AND DUAL-PRODRUGS
    Publication number: 20220356221
    Abstract: The present application relates to novel prodrugs of IL-12. Further included in the present application are methods of making and using the novel prodrugs.
    Type: Application
    Filed: September 28, 2020
    Publication date: November 10, 2022
    Applicant: ASKGENE PHARMA, INC.
    Inventors: Yuefeng LU, Chunxiao YU
  • IL-2 FUSION PROTEINS THAT PREFERENTIALLY BIND IL-2RALPHA
    Publication number: 20220306714
    Abstract: The present disclosure provides novel isolated IL-2 fusion molecules that preferentially activate regulatory T cells (Treg) in vitro and in vivo. Further included are methods of making and using said novel fusion molecules to treat inflammatory and autoimmune diseases.
    Type: Application
    Filed: August 12, 2020
    Publication date: September 29, 2022
    Applicant: ASKGENE PHARMA, INC.
    Inventors: Chen YAO, Chunxiao YU, Yuefeng LU, Liqin LIU, Kurt SHANEBECK, Shiwen ZHANG
  • NOVEL IL-21 PRODRUGS AND METHODS OF USE THEREOF
    Publication number: 20220289822
    Abstract: Provided herein are IL-21 prodrugs and methods of making and using thereof for stimulating the immune system, or treating cancer or an infectious disease.
    Type: Application
    Filed: August 21, 2020
    Publication date: September 15, 2022
    Applicant: ASKGENE PHARMA, INC.
    Inventors: Yuefeng LU, Chunxiao YU, Liqin LIU, Jian-Feng (Jeff) LU, Jui Chang (Ray) CHUANG
  • NOVEL CYTOKINE PRODRUGS
    Publication number: 20210260163
    Abstract: Provided herein are cytokine muteins and cytokine prodrugs and methods of making and using thereof.
    Type: Application
    Filed: March 11, 2019
    Publication date: August 26, 2021
    Applicant: AskGene Pharma, Inc.
    Inventors: Chunxiao YU, Yuefeng LU, Jian-Feng LU
  • Novel IL-21 Prodrugs and Methods of Use Thereof
    Publication number: 20210163562
    Abstract: Provided herein are IL-21 prodrugs and methods of making and using thereof for stimulating the immune system, or treating cancer or an infectious disease.
    Type: Application
    Filed: July 25, 2019
    Publication date: June 3, 2021
    Applicant: ASKGENE PHARMA, INC.
    Inventors: Yuefeng LU, Chunxiao YU
  • NOVEL IL-15 PRODRUGS AND METHODS OF USE THEREOF
    Publication number: 20200392235
    Abstract: Provided herein are IL-15 cytokine prodrugs and methods of making and using thereof.
    Type: Application
    Filed: June 12, 2020
    Publication date: December 17, 2020
    Applicant: ASKGENE PHARMA, INC.
    Inventors: Yuefeng LU, Chunxiao YU, Jian-Feng LU