Abstract: Provided herein are, inter ilia, methods and compositions for the treatment of cancer. The methods include administering a combination of an anti-STAT3-Toll-like receptor 9 (TLR9)-binding conjugate and a checkpoint inhibitor. The anti-STAT3-Toll-like receptor 9 (TLR9)-binding conjugate provide herein may be a CpG moiety bound to an anti-STAT3 siRNA through a covalent linker and the checkpoint inhibitor may be an anti-CTLA4 antibody. Administration of a combined effective amount of the anti-STAT3-Toll-like receptor 9 (TLR9)-binding conjugate and the checkpoint inhibitor results in surprisingly increased anti-tumor efficacy and CDS T cell activity.

Abstract: The present invention provides an openable extended panel, and a lift ceiling, lift car and lift system having same, wherein the openable extended panel is mounted to a support frame and is in positional correspondence to an escape exit at a car roof; the openable extended panel is rotatably connected to the support frame at a first side, and the openable extended panel is connected to the support frame via an intermediate member at a second side opposite to the first side, the support frame and the openable extended panel being respectively detachably connected to the intermediate member. The openable extended panel according to the embodiments of the present invention has a simple structure, and can be easily opened.

Abstract: The present invention relates to a rust removing device for an elevator guide rail and aims at solving a problem of great time and labor taken and insufficient rust removal due to that rust of existing guide rail is removed manually. The rust removing device comprises: a support; a rust removal rack, mounted on the support and covering guide rail; and a rust removal material, arranged on a U-shaped inner wall of the rust removal rack and fitted with a surface of the guide rail. The rust removing device of the present invention has advantages that the rust of the guide rail is removed automatically instead of being removed manually, featured by a high rust removing speed, energy saving, simple maintenance, and less influence on users due to long-time service stop because of rust removal.

Abstract: The present invention provides an openable extended panel, and a lift ceiling, lift car and lift system having same, wherein the openable extended panel is mounted to a support frame and is in positional correspondence to an escape exit at a car roof; the openable extended panel is rotatably connected to the support frame at a first side, and the openable extended panel is connected to the support frame via an intermediate member at a second side opposite to the first side, the support frame and the openable extended panel being respectively detachably connected to the intermediate member. The openable extended panel according to the embodiments of the present invention has a simple structure, and can be easily opened.

Abstract: The present invention relates to a rust removing device for an elevator guide rail and aims at solving a problem of great time and labor taken and insufficient rust removal due to that rust of existing guide rail is removed manually. The rust removing device comprises: a support; a rust removal rack, mounted on the support and covering guide rail; and a rust removal material, arranged on a U-shaped inner wall of the rust removal rack and fitted with a surface of the guide rail. The rust removing device of the present invention has advantages that the rust of the guide rail is removed automatically instead of being removed manually, featured by a high rust removing speed, energy saving, simple maintenance, and less influence on users due to long-time service stop because of rust removal.