Patents by Inventor Chwen-Ming SHIH

Chwen-Ming SHIH has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9005922
    Abstract: The present invention discloses a sensor chip for screening a topoisomerase inhibitor and a screening method thereof. The sensor chip comprises topoisomerase I and a biochip. The topoisomerase I is immobilized on the biochip, and the topoisomerase I has DNA catalytic activity. This provides a rapid screening method for topoisomerase I inhibitors.
    Type: Grant
    Filed: September 21, 2010
    Date of Patent: April 14, 2015
    Assignee: Taipei Medical University
    Inventors: Chun-Mao Lin, Hsiang-Ping Tsai, Chwen-Ming Shih, Jau-Lang Hwang, Chi-Ming Lee
  • Patent number: 8683743
    Abstract: The present invention discloses a grain germinating system comprising a temperature controlling device, an incubation device, a drying device and a monitoring device. The temperature controlling device comprises a heat pump module, an air conditioning module and a piping module. The heat pump module can output a high or low temperature heat exchanging liquid. The temperature of a culture medium of a grain is adjusted by the incubation device. The incubated grain is dried by the drying device. The air conditioning module is for a plant building. The piping module is connected with the heat pump module, and is provided for the high or low temperature heat exchanging liquid to flow. The incubation device and the drying device are heated by the high temperature heat exchanging liquid. The drying device is cooled by the low temperature heat exchanging liquid provided for the air condition of the plant building to use.
    Type: Grant
    Filed: March 22, 2010
    Date of Patent: April 1, 2014
    Assignee: Taipei Medical University
    Inventors: Chun-Mao Lin, Fu-Der Mai, Chien-Lung Hung, Chwen-Ming Shih
  • Publication number: 20110287438
    Abstract: The present invention discloses a sensor chip for screening a topoisomerase inhibitor and a screening method thereof. The sensor chip comprises topoisomerase I and a biochip. The topoisomerase I is immobilized on the biochip, and the topoisomerase I has DNA catalytic activity. This provides a rapid screening method for topoisomerase I inhibitors.
    Type: Application
    Filed: September 21, 2010
    Publication date: November 24, 2011
    Applicant: TAIPEI MEDICAL UNIVERSITY
    Inventors: Chun-Mao Lin, Hsiang-Ping Tsai, Chwen-Ming Shih, Jau-Lang Hwang, Chi Ming Lee
  • Publication number: 20110146148
    Abstract: The present invention discloses a grain germinating system comprising a temperature controlling device, an incubation device, a drying device and a monitoring device. The temperature controlling device comprises a heat pump module, an air conditioning module and a piping module. The heat pump module can output a high or low temperature heat exchanging liquid. The temperature of a culture medium of a grain is adjusted by the incubation device. The incubated grain is dried by the drying device. The air conditioning module is for a plant building. The piping module is connected with the heat pump module, and is provided for the high or low temperature heat exchanging liquid to flow. The incubation device and the drying device are heated by the high temperature heat exchanging liquid. The drying device is cooled by the low temperature heat exchanging liquid provided for the air condition of the plant building to use.
    Type: Application
    Filed: March 22, 2010
    Publication date: June 23, 2011
    Applicant: TAIPEI MEDICAL UNIVERSITY
    Inventors: CHIEN-LUNG HUNG, CHWEN-MING SHIH
  • Publication number: 20100144763
    Abstract: The invention relates to the compounds isolated from Evodia rutaecarpa (Juss.), in that has been demonstrated to inhibit topoisomerase I. Evodiamine, an alkaloidal compound is reported the topoisomerase I inhibitory activity. The effect of evodiamine acts by stabilizing the covalent complex between topoisomerase I and DNA, which results in a blockade of DNA replication and transcription.
    Type: Application
    Filed: December 4, 2009
    Publication date: June 10, 2010
    Applicant: TAIPEI MEDICAL UNIVERSITY
    Inventors: Chun-Mao Lin, Chwen-Ming Shih, Jui-Yu Wu
  • Publication number: 20080311059
    Abstract: A skin whitening composition and a method for the same are provided. The skin whitening composition comprises a far-infrared ray releasing substance having a primary component of an oxide mineral, wherein the skin whitening composition achieves a whitening effect via an irradiation of the far-infrared ray releasing substance. In another aspect, the method comprises the steps of administering a far-infrared ray releasing substance to a subject and reducing melanogenesis of the subject by inhibiting growth of a pigment cell, wherein the far-infrared releasing substance has an oxide mineral.
    Type: Application
    Filed: September 18, 2007
    Publication date: December 18, 2008
    Applicants: NATIONAL APPLIED RESEARCH LABORATORIES, TAIPEI MEDICAL UNIVERSITY
    Inventors: Yung-Sheng LIN, Ming-Yu LIN, Tsung-Tao Huang, Ting-Kai Leung, Chwen-Ming SHIH