Abstract: A surgical instrument with pressure sensing and vision feedback functions has an instrument body and a piezochromic device. The instrument body includes a work piece with a visible surface. The piezochromic device is disposed on the visible surface of the work piece of the instrument body and performs color change when the piezochromic device senses pressure. Therefore, when a doctor performs surgery using the surgical instrument, the doctor can directly see the piezochromic device. When the piezochromic device contacts other surgical instruments or presses organs or tissues within a patient's body, the piezochromic device will change color when the piezochromic device senses the pressure enabling the doctor to adjust the surgical instrument accordingly.