Patents by Inventor Cian Desmond O'Sullivan
Cian Desmond O'Sullivan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230094539Abstract: A portable diagnostic device has a lysate stage (167) with a port for receiving a sample and containing magnetic beads with a probe, and an outlet port. A series of assay stages (161-164) are linked with the lysate vessel, each with a reservoir linked by channels. The final stage (164) has a sensor (169) for detecting beads attached to analyte molecules which have been conveyed according to attachment to probes on beads. Larger transport beads cause reporter beads which are tethered by target NA and probes to be transported to the final sensor stage, where they are released and detected when the transport beads have been removed.Type: ApplicationFiled: October 3, 2022Publication date: March 30, 2023Inventors: Brian O'Farrell, Cian Desmond O'Sullivan, John O'Driscoll, Timothy Cummins, Paul Free, Moira McCarthy, John Walshe
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Patent number: 11459601Abstract: A portable diagnostic device has a lysate stage with a port for receiving a sample and containing magnetic beads with a probe, and an outlet port. A series of assay stages are linked with the lysate vessel, each with a reservoir linked by channels. The final stage has a sensor for detecting beads attached to analyte molecules which have been conveyed according to attachment to probes on beads. Larger transport beads cause reporter beads which are tethered by target NA and probes to be transported to the final sensor stage, where they are released and detected when the transport beads have been removed.Type: GrantFiled: September 6, 2018Date of Patent: October 4, 2022Assignee: Altratech LimitedInventors: Brian O'Farrell, Cian Desmond O'Sullivan, John O'Driscoll, Timothy Cummins, Paul Free, Moira Mccarthy, John Walshe
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Patent number: 11274291Abstract: A method of preparing a nucleic acid sample with target enrichment uses a reaction vessel, within which is added a chelating agent to a sample with heating to about 99° C. to provide a crude lysate. A PNA probe is provided at a concentration sufficient for binding and capture of discernible levels of target nucleic acid. The PNA probe may be attached to beads which are initially embedded in a wax body and are released during the heating so that the y are free to move and come into contact with the PNA probe and target DNA. After binding has occurred, the beads are magnetically attracted back into a pocket along with the wax, which is allowed to solidify before they are removed from the reaction vessel.Type: GrantFiled: November 20, 2018Date of Patent: March 15, 2022Assignee: Altratech LimitedInventors: Brian O'Farrell, Timothy Cummins, Cian Desmond O'Sullivan, Jorge Alvarez-Vicente
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Publication number: 20210292745Abstract: A method of preparing a nucleic acid sample with target enrichment uses a reaction vessel, within which is added a chelating agent to a sample with heating to about 99° C. to provide a crude lysate. A PNA probe is provided at a concentration sufficient for binding and capture of discernible levels of target nucleic acid. The PNA probe may be attached to beads which are initially embedded in a wax body and are released during the heating so that the y are free to move and come into contact with the PNA probe and target DNA. After binding has occurred, the heads are magnetically attracted back into a pocket along with the wax, which is allowed to solidify before they are removed from the reaction vessel.Type: ApplicationFiled: April 7, 2021Publication date: September 23, 2021Inventors: Brian O'Farrell, Timothy Cummins, Cian Desmond O'Sullivan, Jorge Alvarez-Vicente
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Patent number: 10995331Abstract: A method of preparing a nucleic acid sample with target enrichment uses a reaction vessel, within which is added a chelating agent to a sample with heating to about 99° C. to provide a crude lysate. A PNA probe is provided at a concentration sufficient for binding and capture of discernible levels of target nucleic acid. The PNA probe may be attached to beads which are initially embedded in a wax body and are released during the heating so that the y are free to move and come into contact with the PNA probe and target DNA. After binding has occurred, the beads are magnetically attracted back into a pocket along with the wax, which is allowed to solidify before they are removed from the reaction vessel.Type: GrantFiled: November 20, 2018Date of Patent: May 4, 2021Assignee: Altratech LimitedInventors: Brian O'Farrell, Timothy Cummins, Cian Desmond O'Sullivan, Jorge Álvarez-Vicente
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Publication number: 20200216884Abstract: A portable diagnostic device has a lysate stage with a port for receiving a sample and containing magnetic beads with a probe, and an outlet port. A series of assay stages are linked with the lysate vessel, each with a reservoir linked by channels. The final stage has a sensor for detecting beads attached to analyte molecules which have been conveyed according to attachment to probes on beads. Larger transport beads cause reporter beads which are tethered by target NA and probes to be transported to the final sensor stage, where they are released and detected when the transport beads have been removed.Type: ApplicationFiled: September 6, 2018Publication date: July 9, 2020Applicant: ALTRATECH LIMITEDInventors: Brian O'FARRELL, Cian Desmond O'SULLIVAN, John O'DRISCOLL, Timothy CUMMINS, Paul FREE, Moira MCCARTHY, John WALSHE
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Patent number: 10683050Abstract: A universal protector for a bicycle element made up of a shell for protecting the element and a fastener for fastening the shell to the element in which the shell includes a size adapting and adjusting structure to accommodate bicycle elements of different sizes thereby protecting the bicycle and vehicles during transport.Type: GrantFiled: August 4, 2016Date of Patent: June 16, 2020Assignee: BOPWORX LIMITEDInventors: Paul Gerard McGriskin, Ciara Anne McGriskin, Cian Desmond O'Sullivan
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Patent number: 10308317Abstract: A rear derailleur protector for a bicycle comprising a shield to protect the derailleur and mounting means on the shield for mounting the shield on the bicycle, the mounting means being adapted to engage the bicycle and a stand attachable to the derailleur protector to support a bicycle fitted with the derailleur protector in an upright position.Type: GrantFiled: December 17, 2014Date of Patent: June 4, 2019Assignee: BOPWORX LIMITEDInventors: Paul Gerard McGriskin, Ciara Anne McGriskin, Cian Desmond O'Sullivan
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Publication number: 20190085320Abstract: A method of preparing a nucleic acid sample with target enrichment uses a reaction vessel, within which is added a chelating agent to a sample with heating to about 99° C. to provide a crude lysate. A PNA probe is provided at a concentration sufficient for binding and capture of discernible levels of target nucleic acid. The PNA probe may be attached to beads which are initially embedded in a wax body and are released during the heating so that the y are free to move and come into contact with the PNA probe and target DNA. After binding has occurred, the beads are magnetically attracted back into a pocket along with the wax, which is allowed to solidify before they are removed from the reaction vessel.Type: ApplicationFiled: November 20, 2018Publication date: March 21, 2019Applicant: ALTRATECH LIMITEDInventors: Brian O'FARRELL, Timothy CUMMINS, Cian Desmond O'SULLIVAN, Jorge ÁLVAREZ-VICENTE
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Publication number: 20190085319Abstract: A method of preparing a nucleic acid sample with target enrichment uses a reaction vessel, within which is added a chelating agent to a sample with heating to about 99° C. to provide a crude lysate. A PNA probe is provided at a concentration sufficient for binding and capture of discernible levels of target nucleic acid. The PNA probe may be attached to beads which are initially embedded in a wax body and are released during the heating so that the y are free to move and come into contact with the PNA probe and target DNA. After binding has occurred, the beads are magnetically attracted back into a pocket along with the wax, which is allowed to solidify before they are removed from the reaction vessel.Type: ApplicationFiled: November 20, 2018Publication date: March 21, 2019Applicant: ALTRATECH LIMITEDInventors: Brian O'FARRELL, Timothy CUMMINS, Cian Desmond O'SULLIVAN, Jorge ÁLVAREZ-VICENTE
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Patent number: 10160966Abstract: A method of preparing a nucleic acid sample with target enrichment uses a reaction vessel (11), within which is added a chelating agent to a sample with heating to about 99° C. to provide a crude lysate. A PNA probe is provided at a concentration sufficient for binding and capture of discernible levels of target nucleic acid. The PNA probe may be attached to beads (26) which are initially embedded in a wax body (17) and are released during the heating so that they are free to move and come into contact with the PNA probe and target DNA. After binding has occurred, the beads are magnetically attracted back into a pocket (16) along with the wax (17), which is allowed to solidify before they are removed from the reaction vessel.Type: GrantFiled: December 10, 2014Date of Patent: December 25, 2018Assignee: ALTRATECH LIMITEDInventors: Brian O'Farrell, Timothy Cummins, Cian Desmond O'Sullivan, Jorge Álvarez-Vicente
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Publication number: 20180229794Abstract: A universal protector for a bicycle element made up of a shell for protecting the element and a fastener for fastening the shell to the element in which the shell includes a size adapting and adjusting structure to accommodate bicycle elements of different sizes thereby protecting the bicycle and vehicles during transport.Type: ApplicationFiled: August 4, 2016Publication date: August 16, 2018Inventors: Paul Gerard McGriskin, Ciara Anne McGriskin, Cian Desmond O'Sullivan
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Patent number: 10023253Abstract: A bicycle fork protector and stand comprising a wheelset having at least one or two miniature wheels and an axle on the wheelset for engaging a bicycle fork at the bicycle dropouts to protect the fork from damage and maintain the fork blades in a correct spatial arrangement for storage and/or transport of the bicycle.Type: GrantFiled: December 17, 2014Date of Patent: July 17, 2018Assignee: BOPWORX LIMITEDInventors: Paul Gerard McGriskin, Ciara Anne McGriskin, Cian Desmond O'Sullivan
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Publication number: 20180194270Abstract: A spacer for spacing apart two attached articles, particularly for spacing apart bicycles from each other or other articles such as racks to protect the articles comprising a spacer body and engaging means on the spacer body for reversibly attaching the spacer to a first article to prevent impact with a second article, the spacer body being solid or rotatable to correctly orient the spacer and the attached articles.Type: ApplicationFiled: December 17, 2014Publication date: July 12, 2018Inventors: Paul Gerard McGriskin, Ciara Anne McGriskin, Cian Desmond O'Sullivan
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Publication number: 20170001684Abstract: A rear derailleur protector for a bicycle comprising a shield to protect the derailleur and mounting means on the shield for mounting the shield on the bicycle, the mounting means being adapted to engage the bicycle and a stand attachable to the derailleur protector to support a bicycle fitted with the derailleur protector in an upright position.Type: ApplicationFiled: December 17, 2014Publication date: January 5, 2017Inventors: Paul Gerard McGriskin, Ciara Anne McGriskin, Cian Desmond O'Sullivan
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Publication number: 20170001673Abstract: A bicycle fork protector and stand comprising a wheelset having at least one or two miniature wheels and an axle on the wheelset for engaging a bicycle fork at the bicycle dropouts to protect the fork from damage and maintain the fork blades in a correct spatial arrangement for storage and/or transport of the bicycle.Type: ApplicationFiled: December 17, 2014Publication date: January 5, 2017Inventors: Paul Gerard MCGRISKIN, Ciara Anne MCGRISKIN, Cian Desmond O'SULLIVAN
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Publication number: 20160298107Abstract: A method of preparing a nucleic acid sample with target enrichment uses a reaction vessel (11), within which is added a chelating agent to a sample with heating to about 99° C. to provide a crude lysate. A PNA probe is provided at a concentration sufficient for binding and capture of discernible levels of target nucleic acid. The PNA probe may be attached to beads (26) which are initially embedded in a wax body (17) and are released during the heating so that they are free to move and come into contact with the PNA probe and target DNA. After binding has occurred, the beads are magnetically attracted back into a pocket (16) along with the wax (17), which is allowed to solidify before they are removed from the reaction vessel.Type: ApplicationFiled: December 10, 2014Publication date: October 13, 2016Applicant: ALTRATECH LIMITEDInventors: Brian O'FARRELL, Timothy CUMMINS, Cian Desmond O'SULLIVAN, Jorge ÁLVAREZ-VICENTE
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Patent number: D692142Type: GrantFiled: November 27, 2011Date of Patent: October 22, 2013Assignee: Zinc Software Ltd.Inventors: Darran John Hughes, Cian Desmond O'Sullivan