Patents by Inventor Ciara Chamberlain

Ciara Chamberlain has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Granzyme A and granzyme B diagnostics
    Patent number: 9176138
    Abstract: A method for identifying a subject being at risk for or having a chronic inflammatory disease, fibrillinopathy, atherosclerosis, or coronary artery disease is provided. The method may include determining the concentration of GrA and/or GrB in a blood or serum sample from said subject; and comparing the concentrations to the corresponding concentration in a control sample, wherein an elevated concentration of GrA and/or GrB may be indicative of a chronic inflammatory disease, fibrillinopathy, atherosclerosis, or coronary artery disease. The method may further include identifying concentrations of fibrinogen, elastin and/or fibrillin.
    Type: Grant
    Filed: April 25, 2014
    Date of Patent: November 3, 2015
    Assignee: The University of British Columbia
    Inventors: David Granville, Rani Cruz, Ciara Chamberlain, Wendy Boivin, Bruce McManus
  • Treatment of dissection, aneurysm, and atherosclerosis using granzyme B inhibitors
    Patent number: 9060960
    Abstract: A method of medical treatment or prevention of a vasculopathy, comprising administering a therapeutically effective amount of a granzyme B inhibitor to a subject in need thereof is provided. In other aspects uses of Granzyme B inhibitors for treatment or for preparation of medicaments for treatment of a vasculopathy are provided.
    Type: Grant
    Filed: October 1, 2008
    Date of Patent: June 23, 2015
    Assignee: The University of British Columbia
    Inventors: David Granville, Rani Cruz, Ciara Chamberlain, Wendy Boivin, Bruce McManus
  • GRANZYME A AND GRANZYME B DIAGNOSTICS
    Publication number: 20140255953
    Abstract: A method for identifying a subject being at risk for or having a chronic inflammatory disease, fibrillinopathy, atherosclerosis, or coronary artery disease is provided. The method may include determining the concentration of GrA and/or GrB in a blood or serum sample from said subject; and comparing the concentrations to the corresponding concentration in a control sample, wherein an elevated concentration of GrA and/or GrB may be indicative of a chronic inflammatory disease, fibrillinopathy, atherosclerosis, or coronary artery disease. The method may further include identifying concentrations of fibrinogen, elastin and/or fibrillin.
    Type: Application
    Filed: April 25, 2014
    Publication date: September 11, 2014
    Applicant: THE UNIVERSITY OF BRITISH COLUMBIA
    Inventors: David Granville, Rani Cruz, Ciara Chamberlain, Wendy Boivin, Bruce McManus
  • Granzyme A and granzyme B diagnostics
    Patent number: 8715948
    Abstract: A method for identifying a subject being at risk for or having a chronic inflammatory disease, fibrillinopathy, atherosclerosis, or coronary artery disease is provided. The method may include determining the concentration of GrA and/or GrB in a blood or serum sample from said subject; and comparing the concentrations to the corresponding concentration in a control sample, wherein an elevated concentration of GrA and/or GrB may be indicative of a chronic inflammatory disease, fibrillinopathy, atherosclerosis, or coronary artery disease. The method may further include identifying concentrations of fibrinogen, elastin and/or fibrillin.
    Type: Grant
    Filed: April 22, 2013
    Date of Patent: May 6, 2014
    Assignee: The University of British Columbia
    Inventors: David Granville, Rani Cruz, Ciara Chamberlain, Wendy Bolvin, Bruce McManus
  • GRANZYME A AND GRANZYME B DIAGNOSTICS
    Publication number: 20130323749
    Abstract: A method for identifying a subject being at risk for or having a chronic Inflammatory disease, fibrillinopathy, atherosclerosis, or coronary artery disease is provided. The method may include determining the concentration of GrA and/or GrB in a blood or serum sample from said subject; and comparing the concentrations to the corresponding concentration in a control sample, wherein an elevated concentration of GrA and/or GrB may be indicative of a chronic inflammatory disease, fibrillinopathy, atherosclerosis, or coronary artery disease. The method may further include identifying concentrations of fibrinogen, elastin and/or fibrillin.
    Type: Application
    Filed: April 22, 2013
    Publication date: December 5, 2013
    Applicant: THE UNIVERSITY OF BRITISH COLUMBIA
    Inventors: David Granville, Rani Cruz, Ciara Chamberlain, Wendy Boivin, Bruce McManus
  • Granzyme A and granzyme B diagnostics
    Patent number: 8426149
    Abstract: A method for identifying a subject being at risk for or having a chronic inflammatory disease, fibrillinopathy, atherosclerosis, or coronary artery disease is provided. The method may include determining the concentration of GrA and/or GrB in a blood or serum sample from said subject; and comparing the concentrations to the corresponding concentration in a control sample, wherein an elevated concentration of GrA and/or GrB may be indicative of a chronic inflammatory disease, fibrillinopathy, atherosclerosis, or coronary artery disease. The method may further include identifying concentrations of fibrinogen, elastin and/or fibrillin.
    Type: Grant
    Filed: October 1, 2008
    Date of Patent: April 23, 2013
    Assignee: The University of British Columbia
    Inventors: David Granville, Rani Cruz, Ciara Chamberlain, Wendy Boivin, Bruce McManus
  • TREATMENT OF DISSECTION, ANEURYSM, AND ATHEROSCLEROSIS USING GRANZYME B INHIBITORS
    Publication number: 20110229546
    Abstract: A method of medical treatment or prevention of a vasculopathy, comprising administering a therapeutically effective amount of a granzyme B inhibitor to a subject in need thereof is provided. In other aspects uses of Granzyme B inhibitors for treatment or for preparation of medicaments for treatment of a vasculopathy are provided.
    Type: Application
    Filed: October 1, 2008
    Publication date: September 22, 2011
    Applicant: THE UNIVERSITY OF BRITISH COLUMBIA
    Inventors: David Granville, Rani Cruz, Ciara Chamberlain, Wendy Boivin, Bruce McManus
  • GRANZYME A AND GRANZYME B DIAGNOSTICS
    Publication number: 20100317038
    Abstract: A method for identifying a subject being at risk for or having a chronic inflammatory disease, fibrillinopathy, atherosclerosis, or coronary artery disease is provided. The method may include determining the concentration of GrA and/or GrB in a blood or serum sample from said subject; and comparing the concentrations to the corresponding concentration in a control sample, wherein an elevated concentration of GrA and/or GrB may be indicative of a chronic inflammatory disease, fibrillinopathy, atherosclerosis, or coronary artery disease. The method may further include identifying concentrations of fibrinogen, elastin and/or fibrillin.
    Type: Application
    Filed: October 1, 2008
    Publication date: December 16, 2010
    Applicant: THE UNIVERSITY OF BRITISH COLUMBIA
    Inventors: David Granville, Rani Cruz, Ciara Chamberlain, Wendy Boivin, Bruce McManus