Patents by Inventor Ciaran Lawlor

Ciaran Lawlor has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • GLYCAN CONJUGATE COMPOSITIONS AND METHODS
    Publication number: 20250034565
    Abstract: The present disclosure provides methods and compositions for modulating cell surface proteins and receptor complexes using a novel class of glycan conjugates that can be used to engage the signaling pathways within desired c cell types. Such defined cell-targeting bioactive glyco-ligands are directed for cell engagement and activation in therapeutic applications.
    Type: Application
    Filed: March 12, 2024
    Publication date: January 30, 2025
    Inventors: Namita BISARIA, Ryan Alexander FLYNN, Brian GOODMAN, Ciaran LAWLOR
  • GLYCAN MODIFIED NUCLEIC ACIDS, METHODS OF PREPARATION, AND THERAPEUTIC USES
    Publication number: 20240261420
    Abstract: The present disclosure relates to glyconucleic acids, such as glycoRNA and glycoDNA described herein. Provided are glycosylated ribonucleic acid (glycoRNA)-related methods and compositions.
    Type: Application
    Filed: August 1, 2023
    Publication date: August 8, 2024
    Inventors: Ryan Alexander FLYNN, Brian GOODMAN, Ciaran LAWLOR, Namita BISARIA, Richard D. CUMMINGS, Mohui WEI, Carolyn R. BERTOZZI
  • COMPOSITIONS AND METHODS FOR OPTIMIZING TROPISM OF DELIVERY SYSTEMS FOR RNA
    Publication number: 20240200118
    Abstract: The present disclosure details various compositions and/or methods of optimizing delivery systems the localized delivery of nucleic acid sequences, polypeptides or peptides for use in therapeutics and/or diagnostics.
    Type: Application
    Filed: February 16, 2024
    Publication date: June 20, 2024
    Inventors: Inna SHCHERBAKOVA, Grace CHEN, Abril Fleitas BEITANS, Brian GOODMAN, Ciaran LAWLOR, Kevin Yingxin YANG
  • LIPID NANOPARTICLES AND METHODS OF USE THEREOF
    Publication number: 20240130969
    Abstract: The present disclosure provides pharmaceutical compositions comprising lipid nanoparticles capable of delivering polynucleotide payloads to target non-liver organs.
    Type: Application
    Filed: November 28, 2023
    Publication date: April 25, 2024
    Inventors: Muthusamy Jayaraman, Ciaran Lawlor, Brian Goodman
  • GLYCAN MODIFIED NUCLEIC ACIDS, METHODS OF PREPARATION, AND THERAPEUTIC USES
    Publication number: 20240115714
    Abstract: The present disclosure relates to glyconucleic acids, such as glycoRNA and glycoDNA described herein. Provided are glycosylated ribonucleic acid (glycoRNA)-related methods and compositions.
    Type: Application
    Filed: August 3, 2023
    Publication date: April 11, 2024
    Inventors: Ryan Alexander FLYNN, Brian GOODMAN, Ciaran LAWLOR, Namita BISARIA, Richard D. CUMMINGS, Mohui WEI, Carolyn R. BERTOZZI
  • Glycan modified short interfering RNA
    Patent number: 11766481
    Abstract: The present disclosure relates to glycan-modified nucleic acids, including short interfering RNA molecules. The glycan-modified nucleic acids include an oligosaccharide moiety that is bond to the nucleic acid and that contains a multiple antennary complex type N-glycan. The disclosure also relates to pharmaceutical compositions containing such glycan-modified nucleic acids, and methods for making and using such glycan-modified nucleic acids.
    Type: Grant
    Filed: May 26, 2022
    Date of Patent: September 26, 2023
    Assignees: GanNA Bio, Inc., The Children's Medical Center
    Inventors: Ryan A. Flynn, Brian Goodman, Ciaran Lawlor, Namita Bisaria, Richard D. Cummings, Mohui Wei, Carolyn R. Bertozzi
  • GLYCAN MODIFIED NUCLEIC ACIDS, METHODS OF PREPARATION, AND THERAPEUTIC USES
    Publication number: 20220387607
    Abstract: The present disclosure relates to glyconucleic acids, such as glycoRNA and glycoDNA described herein. Provided are glycosylated ribonucleic acid (glycoRNA)-related methods and compositions.
    Type: Application
    Filed: May 26, 2022
    Publication date: December 8, 2022
    Inventors: Ryan A. FLYNN, Brian GOODMAN, Ciaran LAWLOR, Namita BISARIA, Richard D. CUMMINGS, Mohui WEI, Carolyn R. BERTOZZI
  • Inhalable dry powders
    Patent number: 11235112
    Abstract: The invention related to dry powders that contain a therapeutic agent. The dry powders have characteristics, e.g., they are processable and/or dense in therapeutic agent that provide advantages for formulating and delivering therapeutics agents to patients.
    Type: Grant
    Filed: September 15, 2020
    Date of Patent: February 1, 2022
    Assignee: Pulmatrix Operating Company, Inc.
    Inventors: Wesley H. DeHaan, Jean C. Sung, Diana Manzanedo, Ciaran Lawlor, Michael Tauber
  • INHALABLE DRY POWDERS
    Publication number: 20210060268
    Abstract: The invention related to dry powders that contain a therapeutic agent. The dry powders have characterstics, e.g., they are processable and/or dense in therapeutic agent that provide advantages for formulating and delivering therapeutics agents to patients.
    Type: Application
    Filed: September 15, 2020
    Publication date: March 4, 2021
    Inventors: Wesley H. DeHaan, Jean C. Sung, Diana Manzanedo, Ciaran Lawlor, Michael Tauber
  • Inhalable dry powders
    Patent number: 10806871
    Abstract: The invention related to dry powders that contain a therapeutic agent. The dry powders have characteristics, e.g., they are processable and/or dense in therapeutic agent that provide advantages for formulating and delivering therapeutic agents to patients.
    Type: Grant
    Filed: January 27, 2020
    Date of Patent: October 20, 2020
    Assignee: Pulmatrix Operating Company, Inc.
    Inventors: Wesley H. DeHaan, Jean C. Sung, Diana Manzanedo, Ciaran Lawlor, Michael Tauber
  • INHALABLE DRY POWDERS
    Publication number: 20200261667
    Abstract: The invention related to dry powders that contain a therapeutic agent. The dry powders have characteristics, e.g., they are processable and/or dense in therapeutic agent that provide advantages for formulating and delivering therapeutic agents to patients.
    Type: Application
    Filed: January 27, 2020
    Publication date: August 20, 2020
    Inventors: Wesley H. DeHaan, Jean C. Sung, Diana Manzanedo, Ciaran Lawlor, Michael Tauber
  • Methods for producing respirable dry powders
    Patent number: 10589039
    Abstract: The invention related to dry powders that contain a therapeutic agent. The dry powders have characteristics, e.g., they are processable and/or dense in therapeutic agent that provide advantages for formulating and delivering therapeutic agents to patients.
    Type: Grant
    Filed: April 24, 2017
    Date of Patent: March 17, 2020
    Assignee: Pulmatric Operating Company, Inc.
    Inventors: Wesley H. DeHaan, Jean C. Sung, Diana Manzanedo, Ciaran Lawlor, Michael Tauber
  • LIPID NANOPARTICLE COMPOSITIONS
    Publication number: 20180085474
    Abstract: Disclosed herein are nanoparticle compositions including an mRNA and a lipid component and methods of using the same.
    Type: Application
    Filed: January 21, 2016
    Publication date: March 29, 2018
    Inventors: Orn ALMARSSON, Ciaran LAWLOR
  • INHALABLE DRY POWDERS
    Publication number: 20170304564
    Abstract: The invention related to dry powders that contain a therapeutic agent. The dry powders have characteristics, e.g., they are processable and/or dense in therapeutic agent that provide advantages for formulating and delivering therapeutic agents to patients.
    Type: Application
    Filed: April 24, 2017
    Publication date: October 26, 2017
    Inventors: WESLEY H. DeHAAN, JEAN C. SUNG, DIANA MANZANEDO, CIARAN LAWLOR, MICHAEL TAUBER
  • INHALABLE DRY POWDERS
    Publication number: 20150136130
    Abstract: The invention related to dry powders that contain a therapeutic agent. The dry powders have characteristics, e.g., they are processable and/or dense in therapeutic agent that provide advantages for formulating and delivering therapeutic agents to patients.
    Type: Application
    Filed: February 28, 2013
    Publication date: May 21, 2015
    Inventors: Wesley H. DeHaan, Jean C. Sung, Diana Manzanedo, Ciaran Lawlor, Michael Tauber