Patents by Inventor Ciaran O'REILLY

Ciaran O'REILLY has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nicotinamide RIPK1 inhibitors
    Patent number: 11767310
    Abstract: Provided herein are compounds of Formula (I) and pharmaceutically acceptable salts thereof, useful as RIPK1 inhibitors, and pharmaceutical compositions comprising same. Further provided are methods of use and preparation. Also provided are methods of treating Ulcerative Colitis using a compound of Formula (I).
    Type: Grant
    Filed: August 8, 2022
    Date of Patent: September 26, 2023
    Assignee: AbbVie Inc.
    Inventors: Kevin Patrick Cusack, Michael Zeller Hoemann, David Andrew Kinsman, Sami Osman, James Patrick Stambuli, Maria Anastasia Argiriadi, Ciaran O'Reilly, Hannah Dexter, Euan Fordyce, Steve St. Gallay
  • NICOTINAMIDE RIPK1 INHIBITORS
    Publication number: 20230127127
    Abstract: Provided herein are compounds of Formula (I) and pharmaceutically acceptable salts thereof, useful as RIPK1 inhibitors, and pharmaceutical compositions comprising same. Further provided are methods of use and preparation. Also provided are methods of treating Ulcerative Colitis using a compound of Formula (I).
    Type: Application
    Filed: August 8, 2022
    Publication date: April 27, 2023
    Inventors: Kevin Patrick Cusack, Michael Zeller Hoemann, David Andrew Kinsman, Sami Osman, James Patrick Stambuli, Maria Anastasia Argiriadi, Ciaran O'Reilly, Hannah Dexter, Euan Fordyce, Steve St. Gallay
  • 3-Phenyl-7-Hydroxy-Isocoumarins as Macrophage Migration Inhibitory Factor (MIF) Inhibitors
    Publication number: 20190071410
    Abstract: Provided herein are 3-phenyl-7-hydroxy-isocoumarin compounds which are MIF inhibitors; compositions comprising said inhibitors and methods for treating or preventing diseases associated with MIF.
    Type: Application
    Filed: September 13, 2018
    Publication date: March 7, 2019
    Inventors: Seamas Donnelly, David Lloyd, Ciaran O'Reilly, Darren Fayne
  • 3-phenyl-7-hydroxy-isocoumarins as macrophage migration inhibitory factor (MIF) inhibitors
    Patent number: 10106519
    Abstract: Provided herein are 3-phenyl-7-hydroxy-isocoumarin compounds which are MIF inhibitors; compositions comprising said inhibitors and methods for treating or preventing diseases associated with MIF.
    Type: Grant
    Filed: March 27, 2015
    Date of Patent: October 23, 2018
    Assignee: The Provost, Fellows, Foundation Scholars, and the Other Members of Board, of the College of the Holy and Undivided Trinity of Queen Elizabeth, Near Dublin
    Inventors: Seamas Donnelly, David Lloyd, Ciaran O'Reilly, Darren Fayne
  • 3-Phenyl-7-Hydroxy-Isocoumarins as Macrophage Migration Inhibitory Factor (MIF) Inhibitors
    Publication number: 20170144983
    Abstract: Provided herein are 3-phenyl-7-hydroxy-isocoumarin compounds which are MIF inhibitors; compositions comprising said inhibitors and methods for treating or preventing diseases associated with MIF.
    Type: Application
    Filed: March 27, 2015
    Publication date: May 25, 2017
    Inventors: Seamas DONNELLY, David LLOYD, Ciaran O'REILLY, Darren FAYNE