Patents by Inventor Cin-Hao LIN

Cin-Hao LIN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polygonal scaffold and manufacturing method thereof, and protein modulator and manufacturing method thereof
    Patent number: 10443026
    Abstract: A polygonal scaffold includes at least three polyproline II (PPII) helix rods and at least three connectors. Each of the PPII helix rods is composed of a plurality of repeat units represented by Formula (i), and at least one of the PPII helix rods has at least one hydrogen atom of at least one of the repeat units being substituted by a first chemical handle for connecting a ligand. Each of the connectors is a divalent organic group, and every two of the PPII helix rods are connected by one of the connectors to form a closed ring. Therefore, with the uniform composition, the PPII helix rods have a stable helical structure under aqueous conditions, and a desired rigidity can be provided.
    Type: Grant
    Filed: December 25, 2017
    Date of Patent: October 15, 2019
    Assignee: NATIONAL TSING HUA UNIVERSITY
    Inventors: Sheng-Kai Wang, Cin-Hao Lin
  • POLYGONAL SCAFFOLD AND MANUFACTURING METHOD THEREOF, AND PROTEIN MODULATOR AND MANUFACTURING METHOD THEREOF
    Publication number: 20190194590
    Abstract: A polygonal scaffold includes at least three polyproline II (PPII) helix rods and at least three connectors. Each of the PPII helix rods is composed of a plurality of repeat units represented by Formula (i), and at least one of the PPII helix rods has at least one of hydrogen atoms of at least one of the repeat units being substituted by a first chemical handle for connecting a ligand. Each of the connectors is a divalent organic group, and every two of the PPII helix rods are connected by one of the connectors to form a closed ring.
    Type: Application
    Filed: December 25, 2017
    Publication date: June 27, 2019
    Inventors: Sheng-Kai WANG, Cin-Hao LIN