Patents by Inventor Cindy A. Sprecher

Cindy A. Sprecher has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

CYTOKINE RECEPTOR ZCYTOR17 MULTIMERS

Publication number: 20070140964

Abstract: Novel polypeptide combinations, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed for zcytor17-containing multimeric or heterodimer cytokine receptors that may be used as novel cytokine antagonists, and within methods for detecting ligands that stimulate the proliferation and/or development of hematopoietic, lymphoid and myeloid cells in vitro and in vivo. The present invention also includes methods for producing the multimeric or heterodimeric cytokine receptor, uses therefor and antibodies thereto.

Type: Application

Filed: October 26, 2006

Publication date: June 21, 2007

Inventors: Cindy Sprecher, Zeren Gao, Joseph Kuijper, Maria Dasovich, Francis Grant, Scott Presnell, Theodore Whitmore, Angela Hammond, Julia Novak, Jane Gross, Stacey Dillon
CYTOKINE RECEPTOR ZCYTOR17 MULTIMERS

Publication number: 20070140963

Abstract: Novel polypeptide combinations, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed for zcytor17-containing multimeric or heterodimer cytokine receptors that may be used as novel cytokine antagonists, and within methods for detecting ligands that stimulate the proliferation and/or development of hematopoietic, lymphoid and myeloid cells in vitro and in vivo. The present invention also includes methods for producing the multimeric or heterodimeric cytokine receptor, uses therefor and antibodies thereto.

Type: Application

Filed: October 26, 2006

Publication date: June 21, 2007

Inventors: Cindy Sprecher, Zeren Gao, Joseph Kuijper, Maria Dasovich, Francis Grant, Scott Presnell, Theodore Whitmore, Angela Hammond, Julia Novak, Jane Gross, Stacey Dillon
ANTIBODIES TO MURINE ZCYTOR17 LIGAND

Publication number: 20070111266

Abstract: The present invention relates to zcytor17lig polynucleotide, polypeptide and anti-zcytor17 antibody molecules. The zcytor17lig is a novel cytokine. The polypeptides may be used within methods for stimulating the immune system, and proliferation and/or development of hematopoietic cells in vitro and in vivo. The present invention also includes methods for producing the protein, uses therefor and antibodies thereto.

Type: Application

Filed: December 19, 2006

Publication date: May 17, 2007

Inventors: CINDY SPRECHER, Joseph Kuijper, Maria Dasovich, Francis Grant, Angela Hammond, Jane Gross
CYTOKINE RECEPTOR ZCYTOR17

Publication number: 20070105777

Abstract: Novel polypeptides, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed for zcytor17, a novel cytokine receptor. The polypeptides may be used within methods for detecting ligands that stimulate the proliferation and/or development of hematopoietic, lymphoid and myeloid cells in vitro and in vivo. Ligand-binding receptor polypeptides can also be used to block ligand activity in vitro and in vivo. The polynucleotides encoding zcytorl7, are located on chromosome 5, and can be used to identify a region of the genome associated with human disease states. The present invention also includes methods for producing the protein, uses therefor and antibodies thereto.

Type: Application

Filed: January 8, 2007

Publication date: May 10, 2007

Inventors: Cindy Sprecher, Scott Presnell, Zeren Gao, Theodore Whitmore, Joseph Kuijper, Mark Maurer
CYTOKINE ZALPHA11 LIGAND ANTIBODIES

Publication number: 20070098682

Abstract: Antibodies that bind to polypeptides and peptides comprising the sequence of zalpha11 Ligand as shown in SEQ ID NO: 2 are described. The antibodies may bind the full length sequence of 162 amino acid residues or a fragment thereof, including a mature polypeptide of 131 amino acid residues and smaller polypeptide and peptide sequences. The antibodies may include antibodies that are polyclonal, monoclonal, murine, humanized or neutralizing. Methods for producing the antibodies are also described.

Type: Application

Filed: October 19, 2006

Publication date: May 3, 2007

Inventors: Julia Novak, Scott Presnell, Cindy Sprecher, Donald Foster, Richard Holly, Jane Gross, Janet Johnston, Andrew Nelson, Stacey Dillon, Angela Hammond
CYTOKINE ZALPHA11 LIGAND ANTIBODIES

Publication number: 20070098683

Abstract: Antibodies that bind to polypeptides and peptides comprising the sequence of zalpha11 Ligand as shown in SEQ ID NO: 2 are described. The antibodies may bind the full length sequence of 162 amino acid residues or a fragment thereof, including a mature polypeptide of 131 amino acid residues and smaller polypeptide and peptide sequences. The antibodies may include antibodies that are polyclonal, monoclonal, murine, humanized or neutralizing. Methods for producing the antibodies are also described.

Type: Application

Filed: October 19, 2006

Publication date: May 3, 2007

Inventors: Julia Novak, Scott Presnell, Cindy Sprecher, Donald Foster, Richard Holly, Jane Gross, Janet Johnston, Andrew Nelson, Stacey Dillon, Angela Hammond
CYTOKINE ZALPHA11 LIGAND

Publication number: 20070099269

Abstract: Antibodies that bind to polypeptides and peptides comprising the sequence of zalpha11 Ligand as shown in SEQ ID NO: 2 are described. The antibodies may bind the full length sequence of 162 amino acid residues or a fragment thereof, including a mature polypeptide of 131 amino acid residues and smaller polypeptide and peptide sequences. The antibodies may include antibodies that are polyclonal, monoclonal, murine, humanized or neutralizing. Methods for producing the antibodies are also described.

Type: Application

Filed: October 16, 2006

Publication date: May 3, 2007

Inventors: JULIA NOVAK, Scott Presnell, Cindy Sprecher, Donald Foster, Richard Holly, Jane Gross, Janet Johnston, Andrew Nelson, Stacey Dillon, Angela Hammond
CYTOKINE ZALPHA11 LIGAND

Publication number: 20070092485

Abstract: Antibodies that bind to polypeptides and peptides comprising the sequence of zalpha11 Ligand as shown in SEQ ID NO: 2 are described. The antibodies may bind the full length sequence of 162 amino acid residues or a fragment thereof, including a mature polypeptide of 131 amino acid residues and smaller polypeptide and peptide sequences. The antibodies may include antibodies that are polyclonal, monoclonal, murine, humanized or neutralizing. Methods for producing the antibodies are also described.

Type: Application

Filed: October 23, 2006

Publication date: April 26, 2007

Inventors: JULIA NOVAK, Scott Presnell, Cindy Sprecher, Donald Foster, Richard Holly, Jane Gross, Janet Johnston, Andrew Nelson, Stacey Dillon, Angela Hammond
NOVEL HUMAN KUNITZ-TYPE INHIBITORS AND METHODS RELATING THERETO

Publication number: 20070092948

Abstract: The present invention provides isolated DNA molecules comprising a DNA segment encoding novel human Kunitz-type inhibitors. Also provided are DNA constructs comprising a first DNA segment encoding a novel human Kunitz-type inhibitor wherein said first DNA segment is operably linked to additional DNA segments required for the expression for the first DNA segment, as well as host cells containing such DNA constructs and methods for producing proteins from the host cells.

Type: Application

Filed: January 4, 2007

Publication date: April 26, 2007

Inventors: Cindy Sprecher, Walt Kisiel, Donald Foster
MURINE ZCYTOR17 LIGAND POLYPEPTIDES AND POLYNUCLEOTIDES

Publication number: 20070077627

Abstract: The present invention relates to zcytor17lig polynucleotide, polypeptide and anti-zcytor17 antibody molecules. The zcytor17lig is a novel cytokine. The polypeptides may be used within methods for stimulating the immune system, and proliferation and/or development of hematopoietic cells in vitro and in vivo. The present invention also includes methods for producing the protein, uses therefor and antibodies thereto.

Type: Application

Filed: December 13, 2006

Publication date: April 5, 2007

Inventors: Cindy Sprecher, Joseph Kuijper, Maria Dasovich, Francis Grant, Angela Hammond, Jane Gross
CYTOKINE ZALPHA11 LIGAND FUSION PROTEINS

Publication number: 20070066807

Abstract: Antibodies that bind to polypeptides and peptides comprising the sequence of zalpha11 Ligand as shown in SEQ ID NO: 2 are described. The antibodies may bind the full length sequence of 162 amino acid residues or a fragment thereof, including a mature polypeptide of 131 amino acid residues and smaller polypeptide and peptide sequences. The antibodies may include antibodies that are polyclonal, monoclonal, murine, humanized or neutralizing. Methods for producing the antibodies are also described.

Type: Application

Filed: October 20, 2006

Publication date: March 22, 2007

Inventors: JULIA NOVAK, Scott Presnell, Cindy Sprecher, Donald Foster, Richard Holly, Jane Gross, Janet Johnston, Andrew Nelson, Stacey Dillon, Angela Hammond
CYTOKINE ZALPHA11 LIGAND FUSION PROTEINS

Publication number: 20070066808

Abstract: Antibodies that bind to polypeptides and peptides comprising the sequence of zalpha11 Ligand as shown in SEQ ID NO: 2 are described. The antibodies may bind the full length sequence of 162 amino acid residues or a fragment thereof, including a mature polypeptide of 131 amino acid residues and smaller polypeptide and peptide sequences. The antibodies may include antibodies that are polyclonal, monoclonal, murine, humanized or neutralizing. Methods for producing the antibodies are also described.

Type: Application

Filed: October 23, 2006

Publication date: March 22, 2007

Inventors: JULIA NOVAK, Scott Presnell, Cindy Sprecher, Donald Foster, Richard Holly, Jane Gross, Janet Johnston, Andrew Nelson, Stacey Dillon, Angela Hammond
CYTOKINE ZALPHA11 LIGAND ANTIBODIES

Publication number: 20070059825

Abstract: Antibodies that bind to polypeptides and peptides comprising the sequence of zalpha11 Ligand as shown in SEQ ID NO: 2 are described. The antibodies may bind the full length sequence of 162 amino acid residues or a fragment thereof, including a mature polypeptide of 131 amino acid residues and smaller polypeptide and peptide sequences. The antibodies may include antibodies that are polyclonal, monoclonal, murine, humanized or neutralizing. Methods for producing the antibodies are also described.

Type: Application

Filed: October 19, 2006

Publication date: March 15, 2007

Inventors: Julia Novak, Scott Presnell, Cindy Sprecher, Donald Foster, Richard Holly, Jane Gross, Janet Johnston, Andrew Nelson, Stacey Dillon, Angela Hammond
Soluble zalpha11 cytokine receptors

Patent number: 7189695

Abstract: Novel polypeptide combinations, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed for soluble zalpha11 receptors that may be used as novel cytokine antagonists, and within methods for detecting ligands that stimulate the proliferation and/or development of hematopoietic, lymphoid and myeloid cells in vitro and in vivo. Ligand-binding receptor polypeptides can also be used to block zlapha11 Ligand activity in vitro and in vivo, and may be used in conjunction with zalpha11 Ligand and other cytokines to selectively stimulate the immune system. The present invention also includes methods for producing the protein, uses therefor and antibodies thereto.

Type: Grant

Filed: June 18, 2004

Date of Patent: March 13, 2007

Assignee: ZymoGenetics, Inc.

Inventors: Cindy A. Sprecher, Julia E. Novak, James W. West, Richard D. Holly, Andrew J. Nelson
CYTOKINE ZALPHA11 LIGAND ANTIBODIES

Publication number: 20070054320

Abstract: Antibodies that bind to polypeptides and peptides comprising the sequence of zalpha11 Ligand as shown in SEQ ID NO: 2 are described. The antibodies may bind the full length sequence of 162 amino acid residues or a fragment thereof, including a mature polypeptide of 131 amino acid residues and smaller polypeptide and peptide sequences. The antibodies may include antibodies that are polyclonal, monoclonal, murine, humanized or neutralizing. Methods for producing the antibodies are also described.

Type: Application

Filed: October 19, 2006

Publication date: March 8, 2007

Inventors: Julia Novak, Scott Presnell, Cindy Sprecher, Donald Foster, Richard Holly, Jane Gross, Janet Johnston, Andrew Nelson, Stacey Dillon, Angela Hammond
CYTOKINE RECEPTOR ZCYTOR17 MULTIMERS

Publication number: 20070048835

Abstract: Novel polypeptide combinations, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed for zcytor17-containing multimeric or heterodimer cytokine receptors that may be used as novel cytokine antagonists, and within methods for detecting ligands that stimulate the proliferation and/or development of hematopoietic, lymphoid and myeloid cells in vitro and in vivo. The present invention also includes methods for producing the multimeric or heterodimeric cytokine receptor, uses therefor and antibodies thereto.

Type: Application

Filed: October 25, 2006

Publication date: March 1, 2007

Inventors: Cindy Sprecher, Zeren Gao, Joseph Kuijper, Maria Dasovich, Francis Grant, Scott Presnell, Theodore Whitmore, Angela Hammond, Julia Novak, Jane Gross, Stacey Dillon
NUCLEIC ACID ENCODING CYTOKINE RECEPTOR ZCYTOR17

Publication number: 20070048308

Abstract: Novel polypeptides, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed for zcytor17, a novel cytokine receptor. The polypeptides may be used within methods for detecting ligands that stimulate the proliferation and/or development of hematopoietic, lymphoid and myeloid cells in vitro and in vivo. Ligand-binding receptor polypeptides can also be used to block ligand activity in vitro and in vivo. The polynucleotides encoding zcytor17, are located on chromosome 5, and can be used to identify a region of the genome associated with human disease states. The present invention also includes methods for producing the protein, uses therefor and antibodies thereto.

Type: Application

Filed: October 20, 2006

Publication date: March 1, 2007

Inventors: Cindy Sprecher, Scott Presnell, Zeren Gao, Theodore Whitmore, Joseph Kuijper, Mark Maurer
NUCLEIC ACID ENCODING CYTOKINE RECEPTOR ZCYTOR17

Publication number: 20070048307

Abstract: Novel polypeptides, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed for zyctor17, a novel cytokine receptor. The polypeptides may be used within methods for detecting ligands that stimulate the proliferation and/or development of hematopoietic, lymphoid and myeloid cells in vitro and in vivo. Ligand-binding receptor polypeptides can also be used to block ligand activity in vitro and in vivo. The polynucleotides encoding zyctor17, are located on chromosome 5, and can be used to identify a region of the genome associated with human disease states. The present invention also includes methods for producing the protein, uses therefor and antibodies thereto.

Type: Application

Filed: October 20, 2006

Publication date: March 1, 2007

Inventors: Cindy Sprecher, Scott Presnell, Zeren Gao, Theodore Whitmore, Joseph Kuijper, Mark Maurer
CYTOKINE RECEPTOR ZCYTOR17 MULTIMERS

Publication number: 20070048222

Abstract: Novel polypeptide combinations, polynucleotides encoding the polypeptides, and related compositions and methods are disclosed for zcytor17-containing multimeric or heterodimer cytokine receptors that may be used as novel cytokine antagonists, and within methods for detecting ligands that stimulate the proliferation and/or development of hematopoietic, lymphoid and myeloid cells in vitro and in vivo. The present invention also includes methods for producing the multimeric or heterodimeric cytokine receptor, uses therefor and antibodies thereto.

Type: Application

Filed: October 27, 2006

Publication date: March 1, 2007

Inventors: Cindy Sprecher, Zeren Gao, Joseph Kuijper, Maria Dasovich, Francis Grant, Scott Presnell, Theodore Whitmore, Angela Hammond, Julia Novak, Jane Gross, Stacey Dillon
CYTOKINE ZALPHA11 LIGAND

Publication number: 20070048259

Abstract: Antibodies that bind to polypeptides and peptides comprising the sequence of zalpha11 Ligand as shown in SEQ ID NO: 2 are described. The antibodies may bind the full length sequence of 162 amino acid residues or a fragment thereof, including a mature polypeptide of 131 amino acid residues and smaller polypeptide and peptide sequences. The antibodies may include antibodies that are polyclonal, monoclonal, murine, humanized or neutralizing. Methods for producing the antibodies are also described.

Type: Application

Filed: October 20, 2006

Publication date: March 1, 2007

Inventors: Julia Novak, Scott Presnell, Cindy Sprecher, Donald Foster, Richard Holly, Jane Gross, Janet Johnston, Andrew Nelson, Stacey Dillon, Angela Hammond

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