Patents by Inventor Cindy CASTELLE

Cindy CASTELLE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ENZYMES WITH RUVC DOMAINS
    Publication number: 20240110167
    Abstract: The present disclosure provides for endonuclease enzymes having distinguishing domain features, as well as methods of using such enzymes or variants thereof.
    Type: Application
    Filed: October 17, 2023
    Publication date: April 4, 2024
    Inventors: Brian C. THOMAS, Christopher BROWN, Daniela S.A. GOLTSMAN, Cristina BUTTERFIELD, Lisa ALEXANDER, Cindy CASTELLE
  • CLASS II, TYPE V CRISPR SYSTEMS
    Publication number: 20240093239
    Abstract: Described herein are methods, compositions, and systems derived from uncultivated microorganisms useful for gene editing.
    Type: Application
    Filed: April 18, 2023
    Publication date: March 21, 2024
    Inventors: Brian THOMAS, Christopher BROWN, Audra DEVOTO, Cristina BUTTERFIELD, Lisa ALEXANDER, Daniela S.A. GOLTSMAN, Justine ALBERS, Alan BROOKS, Greg COST, Morayma TEMOCHE-DIAZ, Cindy CASTELLE, Rebecca LAMOTHE
  • BASE EDITING ENZYMES
    Publication number: 20230374482
    Abstract: The present disclosure provides for endonuclease enzymes having distinguishing domain features, as well as methods of using such enzymes or variants thereof.
    Type: Application
    Filed: May 31, 2023
    Publication date: November 23, 2023
    Inventors: Brian C. THOMAS, Alan BROOKS, Cristina BUTTERFIELD, Christopher BROWN, Cindy CASTELLE, Jyun-Liang LIN
  • BASE EDITING ENZYMES
    Publication number: 20230348877
    Abstract: The present disclosure provides for endonuclease enzymes having distinguishing domain features, as well as methods of using such enzymes or variants thereof.
    Type: Application
    Filed: March 8, 2023
    Publication date: November 2, 2023
    Inventors: Jyun-Liang LIN, Alan BROOKS, Cristina BUTTERFIELD, Christopher BROWN, Cindy CASTELLE, Brian C. Thomas
  • BASE EDITING ENZYMES
    Publication number: 20230348876
    Abstract: The present disclosure provides for endonuclease enzymes having distinguishing domain features, as well as methods of using such enzymes or variants thereof.
    Type: Application
    Filed: March 7, 2023
    Publication date: November 2, 2023
    Inventors: Jyun-Liang LIN, Alan BROOKS, Cristina BUTTERFIELD, Christopher BROWN, Cindy CASTELLE, Brian C. Thomas
  • Class II, type V CRISPR systems
    Patent number: 11713471
    Abstract: Described herein are methods, compositions, and systems derived from uncultivated microorganisms useful for gene editing.
    Type: Grant
    Filed: March 28, 2022
    Date of Patent: August 1, 2023
    Assignee: METAGENOMI, INC.
    Inventors: Brian Thomas, Christopher Brown, Audra Devoto, Cristina Butterfield, Lisa Alexander, Daniela S. A. Goltsman, Justine Albers, Alan Brooks, Greg Cost, Morayma Temoche-Diaz, Cindy Castelle, Rebecca Lamothe
  • CLASS II, TYPE V CRISPR SYSTEMS
    Publication number: 20230227857
    Abstract: Described herein are methods, compositions, and systems derived from uncultivated microorganisms useful for gene editing.
    Type: Application
    Filed: September 6, 2022
    Publication date: July 20, 2023
    Inventors: Brian THOMAS, Christopher BROWN, Audra DEVOTO, Cristina BUTTERFIELD, Lisa ALEXANDER, Daniela S.A. GOLTSMAN, Justine B. ALBERS, Alan BROOKS, Greg COST, Morayma TEMOCHE-DIAZ, Cindy CASTELLE, Rebecca LAMOTHE
  • BASE EDITING ENZYMES
    Publication number: 20220364067
    Abstract: The present disclosure provides for endonuclease enzymes having distinguishing domain features, as well as methods of using such enzymes or variants thereof.
    Type: Application
    Filed: June 15, 2022
    Publication date: November 17, 2022
    Inventors: Jyun-Liang LIN, Alan BROOKS, Cristina BUTTERFIELD, Christopher BROWN, Cindy CASTELLE
  • CLASS II, TYPE V CRISPR SYSTEMS
    Publication number: 20220290187
    Abstract: Described herein are methods, compositions, and systems derived from uncultivated microorganisms useful for gene editing.
    Type: Application
    Filed: March 28, 2022
    Publication date: September 15, 2022
    Inventors: Brian C. THOMAS, Christopher BROWN, Audra DEVOTO, Cristina BUTTERFIELD, Lisa ALEXANDER, Daniela S.A. GOLTSMAN, Justine B. ALBERS, Alan BROOKS, Greg COST, Morayma TEMOCHE-DIAZ, Cindy CASTELLE, Rebecca LAMOTHE