Patents by Inventor CINDY CLEYPOOL

CINDY CLEYPOOL has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250128064
    Abstract: Stimulation of neural activity in a nerve supplying the spleen, wherein the nerve is adjacent to the splenic artery at a position where the splenic artery is not in direct contact with the pancreas, can modulate pro-and anti-inflammatory molecules levels, thereby reducing inflammation and providing ways of treating disorders, such as disorders associated with inflammation. The invention provides improved ways of reducing inflammation with minimized off-target effects, in particular surgical trauma.
    Type: Application
    Filed: October 29, 2024
    Publication date: April 24, 2025
    Inventors: Margarita J. Vervoordeldonk, Eric Irwin, Daniel John Chew, Matteo Donega, Cindy Cleypool, Isha Gupta
  • Patent number: 12161869
    Abstract: Stimulation of neural activity in a nerve supplying the spleen, wherein the nerve is adjacent to the splenic artery at a position where the splenic artery is not in direct contact with the pancreas, can modulate pro- and anti-inflammatory molecules levels, thereby reducing inflammation and providing ways of treating disorders, such as disorders associated with inflammation. The invention provides improved ways of reducing inflammation with minimized off-target effects, in particular surgical trauma.
    Type: Grant
    Filed: April 27, 2023
    Date of Patent: December 10, 2024
    Assignee: Galvani Bioelectronics Limited
    Inventors: Margarita J. Vervoordeldonk, Eric Irwin, Daniel John Chew, Matteo Donega, Cindy Cleypool, Isha Gupta
  • Publication number: 20230271010
    Abstract: Stimulation of neural activity in a nerve supplying the spleen, wherein the nerve is adjacent to the splenic artery at a position where the splenic artery is not in direct contact with the pancreas, can modulate pro- and anti-inflammatory molecules levels, thereby reducing inflammation and providing ways of treating disorders, such as disorders associated with inflammation. The invention provides improved ways of reducing inflammation with minimized off-target effects, in particular surgical trauma.
    Type: Application
    Filed: April 27, 2023
    Publication date: August 31, 2023
    Inventors: Margarita J. Vervoordeldonk, Eric Irwin, Daniel John Chew, Matteo Donega, Cindy Cleypool, Isha Gupta
  • Patent number: 11738196
    Abstract: Stimulation of neural activity in a nerve supplying the spleen, wherein the nerve is adjacent to the splenic artery at a position where the splenic artery is not in direct contact with the pancreas, can modulate pro- and anti-inflammatory molecules levels, thereby reducing inflammation and providing ways of treating disorders, such as disorders associated with inflammation. The invention provides improved ways of reducing inflammation with minimized off-target effects, in particular surgical trauma.
    Type: Grant
    Filed: July 25, 2022
    Date of Patent: August 29, 2023
    Assignee: Galvani Bioelectronics Limited
    Inventors: Margarita J. Vervoordeldonk, Eric Irwin, Daniel John Chew, Matteo Donega, Cindy Cleypool, Isha Gupta
  • Patent number: 11633601
    Abstract: Modulation of the neural activity of a nerve adjacent to the left gastro epiploic artery (LGEA) and/or a nerve adjacent to a short gastric artery (SGA) can modulate the neural activity of the sympathetic nerves that impact splenic function. This is useful for reducing inflammation and providing ways of treating inflammatory disorders.
    Type: Grant
    Filed: December 20, 2018
    Date of Patent: April 25, 2023
    Assignee: Galvani Bioelectronics Limited
    Inventors: Margarita J. Vervoordeldonk, Robert Coatney, Cindy Cleypool
  • Publication number: 20220409895
    Abstract: Stimulation of neural activity in a nerve supplying the spleen, wherein the nerve is adjacent to the splenic artery at a position where the splenic artery is not in direct contact with the pancreas, can modulate pro- and anti-inflammatory molecules levels, thereby reducing inflammation and providing ways of treating disorders, such as disorders associated with inflammation. The invention provides improved ways of reducing inflammation with minimized off-target effects, in particular surgical trauma.
    Type: Application
    Filed: July 25, 2022
    Publication date: December 29, 2022
    Inventors: Margarita J. Vervoordeldonk, Eric Irwin, Daniel John Chew, Matteo Donega, Cindy Cleypool, Isha Gupta
  • Patent number: 11446496
    Abstract: Stimulation of neural activity in a nerve supplying the spleen, wherein the nerve is adjacent to the splenic artery at a position where the splenic artery is not in direct contact with the pancreas, can modulate pro- and anti-inflammatory molecules levels, thereby reducing inflammation and providing ways of treating disorders, such as disorders associated with inflammation. The invention provides improved ways of reducing inflammation with minimized off-target effects, in particular surgical trauma.
    Type: Grant
    Filed: December 20, 2018
    Date of Patent: September 20, 2022
    Assignee: Galvani Bioelectronics Limited
    Inventors: Margarita J. Vervoordeldonk, Eric Irwin, Daniel John Chew, Matteo Donega, Cindy Cleypool, Isha Gupta
  • Publication number: 20210093862
    Abstract: Stimulation of neural activity in a nerve supplying the spleen, wherein the nerve is adjacent to the splenic artery at a position where the splenic artery is not in direct contact with the pancreas, can modulate pro- and anti-inflammatory molecules levels, thereby reducing inflammation and providing ways of treating disorders, such as disorders associated with inflammation. The invention provides improved ways of reducing inflammation with minimized off-target effects, in particular surgical trauma.
    Type: Application
    Filed: December 20, 2018
    Publication date: April 1, 2021
    Inventors: MARGRIET VERVOORDELDONK, ERIC IRWIN, DANIEL JOHN CHEW, MATTEO DONEGA, CINDY CLEYPOOL, ISHA GUPTA
  • Publication number: 20200391036
    Abstract: Modulation of the neural activity of a nerve adjacent to the left gastro epiploic artery (LGEA) and/or a nerve adjacent to a short gastric artery (SGA) can modulate the neural activity of the sympathetic nerves that impact splenic function. This is useful for reducing inflammation and providing ways of treating inflammatory disorders.
    Type: Application
    Filed: December 20, 2018
    Publication date: December 17, 2020
    Inventors: MARGRIET VERVOORDELDONK, ROBERT COATNEY, CINDY CLEYPOOL