Abstract: Embodiments involve optical waveguides with spongy material for cladding or layers that include compressible gas pockets. The refractive index of the porous cladding material will change when compressed, bent, or stretched. Measurements for pressure, strain, bending, etc., may be obtained by monitoring the signal degradation and/or escape of radiant energy, e.g., IR, etc., from the core and out through the spongy cladding, where it may be picked up by a neighboring core. Optical waveguides configured as fibers may be easily sewn to stretchable materials, such as athletic tape, fabrics used in umbrellas, balloons, fabrics used in clothing, etc., to meet a robust number of applications.

Abstract: Radial-armed thin-film bilayers are designed and fabricated from a metal and an oxide to produce grippers that interact with the yarns or fibers of the fabric and form a mechanical tangle attachment to the fabric. MEMs devices attached to the grippers enable the MEMs devices to be adhered to a flexible and/or extensible fabric. Fabrics comprise conventional textile, smart textiles, functional fibers or other smart materials. The fabrics thus incorporate wearable sensors, medical devices, and other functional MEMs for commercial, biomedical, industrial and scientific applications.

Abstract: Embodiments involve optical waveguides with spongy material for cladding or layers that include compressible gas pockets. The refractive index of the porous cladding material will change when compressed, bent, or stretched. Measurements for pressure, strain, bending, etc., may be obtained by monitoring the signal degradation and/or escape of radiant energy, e.g., IR, etc., from the core and out through the spongy cladding, where it may be picked up by a neighboring core. Optical waveguides configured as fibers may be easily sewn to stretchable materials, such as athletic tape, fabrics used in umbrellas, balloons, fabrics used in clothing, etc., to meet a robust number of applications.

Abstract: A system for collecting data includes a remote sensor assembly and a central data collection device. The remote sensor assembly has a data bus, a remote wireless node, and a plurality of remote sensor modules in wired communication with the remote wireless node via the data bus. Each of the remote sensor modules converts a sensed condition into data in response to a request from the remote wireless node. The central data collection device has a master wireless node for periodically wirelessly communicating with the remote wireless node. The remote wireless node collects data from each of the plurality of remote sensor modules and periodically transmits the data to the master wireless node. The remote sensor modules are interchangeable and new remote sensor modules may be added. The remote wireless node may detect the sequence of the attached remote sensor modules to enable three-dimensional mapping of the sensed conditions.

Abstract: A system for collecting data includes a remote sensor assembly and a central data collection device. The remote sensor assembly has a data bus, a remote wireless node, and a plurality of remote sensor modules in wired communication with the remote wireless node via the data bus. Each of the remote sensor modules converts a sensed condition into data in response to a request from the remote wireless node. The central data collection device has a master wireless node for periodically wirelessly communicating with the remote wireless node. The remote wireless node collects data from each of the plurality of remote sensor modules and periodically transmits the data to the master wireless node. The remote sensor modules are interchangeable and new remote sensor modules may be added. The remote wireless node may detect the sequence of the attached remote sensor modules to enable three-dimensional mapping of the sensed conditions.

Abstract: A microfluidic flow cytometry device includes a substrate and transverse electrodes formed on the substrate. An elastomer microfluidic focusing channel system formed on the substrate focuses a sample stream onto the floor of an outlet channel that is substantially wider and taller than cells or particles of interest and that has the transverse electrodes disposed in its floor upstream of an exit site. A step in the outlet channel upstream of the transverse electrodes vertically confines sample stream flow onto the floor of the outlet channel over the transverse electrodes. Buffer inlet channels introduce a buffer stream for horizontal focusing of the sample stream into the central region of the outlet channel at the transverse electrodes. A sample inlet channel is smaller in vertical height than the buffer inlet channels for introducing a sample stream such that the buffer vertically focuses the sample stream away from the top of the outlet channel.

Abstract: A device for measuring fluid flow rates over a wide range of flow rates (<1 nL/min to >10 ?L/min) and at pressures at least as great as 2,000 psi. The invention is particularly adapted for use in microfluidic systems. The device operates by producing compositional variations in the fluid, or pulses, that are subsequently detected downstream from the point of creation to derive a flow rate. Each pulse, comprising a small fluid volume, whose composition is different from the mean composition of the fluid, can be created by electrochemical means, such as by electrolysis of a solvent, electrolysis of a dissolved species, or electrodialysis of a dissolved ionic species. Measurements of the conductivity of the fluid can be used to detect the arrival time of the pulses, from which the fluid flow rate can be determined. A pair of spaced apart electrodes can be used to produce the electrochemical pulse.

Abstract: An apparatus that couples automated injection with flow feedback to provide nanoliter accuracy in controlling microliter volumes. The apparatus comprises generally a source of hydraulic fluid pressure, a fluid isolator joined to the outlet of the hydraulic pressure source and a flow sensor to provide pressure-driven analyte metering. For operation generally and particularly in microfluidic systems the hydraulic pressure source is typically an electrokinetic (EK) pump that incorporates gasless electrodes. The apparatus is capable of metering sub-microliter volumes at flowrates of 1–100 ?L/min into microsystem load pressures of up to 1000–50 psi, respectively. Flowrates can be specified within 0.5 ?L/min and volumes as small as 80 nL can be metered.

Abstract: An electrode device for high pressure applications. These electrodes, designed to withstand pressure of greater than 10,000 psi, are adapted for use in microfluidic devices that employ electrokinetic or electrophoretic flow. The electrode is composed, generally, of an outer electrically insulating tubular body having a porous ceramic frit material disposed in one end of the outer body. The pores of the porous ceramic material are filled with an ion conductive polymer resin. A conductive material situated on the upper surface of the porous ceramic frit material and, thus isolated from direct contact with the electrolyte, forms a gas diffusion electrode. A metal current collector, in contact with the gas diffusion electrode, provides connection to a voltage source.

Abstract: An electrode device for high pressure applications. These electrodes, designed to withstand pressure of greater than 10,000 psi, are adapted for use in microfluidic devices that employ electrokinetic or electrophoretic flow. The electrode is composed, generally, of an outer electrically insulating tubular body having a porous ceramic frit material disposed in one end of the outer body. The pores of the porous ceramic material are filled with an ion conductive polymer resin. A conductive material situated on the upper surface of the porous ceramic frit material and, thus isolated from direct contact with the electrolyte, forms a gas diffusion electrode. A metal current collector, in contact with the gas diffusion electrode, provides connection to a voltage source.

Abstract: A polycarbonate polymer such as poly(cyclohexene carbonate) acts as a positive electron beam resist, is substantially transparent to ultra violet light and that depolymerizes when heated. The polymer acts as a positive electron beam resist at 5 kV, and depolymerizes at temperatures between approximately 200-300° C. The polymer is removable from underneath other layers by heating, facilitating fabrication of overhanging structures such as tubes by depositing layers on top of the polymer.

Abstract: A device for measuring fluid flow rates over a wide range of flow rates (<1 nL/min to >10 &mgr;L/min) and at pressures at least as great as 10,000 psi. The invention is particularly adapted for use in microfluidic systems. The device operates by producing compositional variations in the fluid, or pulses, that are subsequently detected downstream from the point of creation to derive a flow rate. Each pulse, comprising a small fluid volume, whose composition is different from the mean composition of the fluid, can be created by electrochemical means, such as by electrolysis of a solvent, electrolysis of a dissolved species, or electrodialysis of a dissolved ionic species.

Abstract: A polycarbonate polymer such as poly(cyclohexene carbonate) acts as a positive electron beam resist, is substantially transparent to ultra violet light and that depolymerizes when heated. The polymer acts as a positive electron beam resist at 5 kV, and depolymerizes at temperatures between approximately 200-300° C. The polymer is removable from underneath other layers by heating, facilitating fabrication of overhanging structures such as tubes by depositing layers on top of the polymer.

Abstract: The present invention provides a method of patterning a self-assembled monolayer (SAM) on a substrate comprising employing low electron-beam lithography to selectively deactivate functional groups at the surface of said SAM in a preselected area of said surface, wherein said functional groups bind to a target substance but said deactivated functional groups do not, so that the surface of said SAM can be contacted with said target substance so that the target substance binds to said functional groups but does not bind to said deactivated groups in said preselected area, to yield a pattern of said target substance on said surface.